iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062096

UUCD1 version

UUC-MoD-01057

Ensembl Protein ID

ENSMODP00000025939.3

UniProt Accession

F7AN44; F7AN44_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020740.3	ENSMODT00000026403.3	ENSMODP00000025939.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.00e-213	707.9	448	935

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++t++D d +e+snlnrqFLfr+++++k+K+ +aa+a   
   Q: 448  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtgkekGMVTITDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAAATLS 536
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +n + ++e+h +++++ +e ++   F++k dv+v+aldn+earr+v+++cl++ +pl++sgt+G++G+++ ii++lte+y++++dpp++
   Q: 537  INAQLKIESHLNKVCPATEMVYsdeFYTKQDVIVTALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEAIIPHLTESYNSHRDPPEE 625
           ********************99******************************************************************* PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl++++s e++eg+++v  ++ s++++n++ ++e+a+ +f+
   Q: 626  EIPFCTLKSFPAAIEHTIQWArdkfeslfsqkpSLFNKFWQTYSSAEEVLQRIQSGESLEGCFQV-IKILSRRPRNWSHCVELARMKFE 713
           *****************************************************************.9********************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 714  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfefndplhfnfiqtaaklfatiyfipftekdlsvevfssilskleipEFKP 802
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l+ ++ ++ ++k+++++ +lsfekddds  ++d++taa+nlra++++iep +d+ ++k+
   Q: 803  SNKVVQTDETARKPDHVPVSSEDernavFQLENAISSNEATKSDLQMVVLSFEKDDDSngHIDFITAASNLRAKMYNIEP-ADRLKTKR 890
           ****************998888899*******************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 891  IAGKIIPAIATSTAAVSGLVALELIKVAGGhPFEAYKNCFLNLAI 935
           ******************************99*********9886 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEEADSLPPP GGEEAIPSSA AADPGETSST NKYSPNMSTD SMEIDDALYS RQRYVLGDSA 60
MQKMAKSHVF LSGMGGLGVE IAKNIVLAGI KSLTIHDTKQ CQAWDIGTNF FICEDDVVNR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCCCCCG TGACCCCCAA GGCCCCGCCC CGTTCCCTGC CTCCCTTGGG CGGCGGCAGC 60
AGCAGCAGCA GCAGCAGTAG CAGTAGTCTT AGCAGCAGAA GCAGCAGAAG CAGCAGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100012977

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	84.96	0.00e+00	1891.00
IUUC-Apl-004158	Anas platyrhynchos	82.54	0.00e+00	1751.00
IUUC-Aca-005349	Anolis carolinensis	81.68	0.00e+00	1782.00
IUUC-Bta-012696	Bos taurus	85.07	0.00e+00	1883.00
IUUC-Cja-019563	Callithrix jacchus	84.48	0.00e+00	1865.00
IUUC-Cfa-020951	Canis familiaris	85.24	0.00e+00	1902.00
IUUC-Cpo-022307	Cavia porcellus	82.03	0.00e+00	1819.00
IUUC-Csa-023647	Chlorocebus sabaeus	84.58	0.00e+00	1877.00
IUUC-Cho-024682	Choloepus hoffmanni	73.01	0.00e+00	900.00
IUUC-Dre-028022	Danio rerio	67.94	0.00e+00	1483.00
IUUC-Dno-029796	Dasypus novemcinctus	87.00	0.00e+00	1865.00
IUUC-Dor-030981	Dipodomys ordii	71.03	0.00e+00	1432.00
IUUC-Ete-032514	Echinops telfairi	73.91	0.00e+00	1089.00
IUUC-Eca-033697	Equus caballus	86.10	0.00e+00	1891.00
IUUC-Eeu-035323	Erinaceus europaeus	78.12	0.00e+00	1256.00
IUUC-Fca-035858	Felis catus	86.10	0.00e+00	1889.00
IUUC-Fal-036848	Ficedula albicollis	81.78	0.00e+00	1752.00
IUUC-Gmo-039326	Gadus morhua	67.09	0.00e+00	1409.00
IUUC-Gga-040747	Gallus gallus	82.27	0.00e+00	1749.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.18	0.00e+00	1389.00
IUUC-Ggo-044577	Gorilla gorilla	84.12	0.00e+00	1868.00
IUUC-Hsa-046007	Homo sapiens	84.30	0.00e+00	1862.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	88.20	0.00e+00	1004.00
IUUC-Lch-049992	Latimeria chalumnae	74.63	0.00e+00	1563.00
IUUC-Loc-051899	Lepisosteus oculatus	70.49	0.00e+00	1522.00
IUUC-Laf-054413	Loxodonta africana	87.18	0.00e+00	1790.00
IUUC-Mcc-054656	Macaca mulatta	84.48	0.00e+00	1871.00
IUUC-Meu-056463	Macropus eugenii	78.90	0.00e+00	1534.00
IUUC-Mga-059721	Meleagris gallopavo	79.14	0.00e+00	1647.00
IUUC-Mmr-060908	Microcebus murinus	81.46	0.00e+00	1815.00
IUUC-Mmu-064114	Mus musculus	85.77	0.00e+00	1873.00
IUUC-Mpu-066017	Mustela putorius furo	84.96	0.00e+00	1900.00
IUUC-Mlu-068037	Myotis lucifugus	82.97	0.00e+00	1814.00
IUUC-Nle-069494	Nomascus leucogenys	84.01	0.00e+00	1860.00
IUUC-Opr-070910	Ochotona princeps	61.75	3.00e-161	562.00
IUUC-Ont-071592	Oreochromis niloticus	68.82	0.00e+00	1459.00
IUUC-Oan-073268	Ornithorhynchus anatinus	82.11	0.00e+00	1629.00
IUUC-Ocu-074296	Oryctolagus cuniculus	86.58	0.00e+00	1893.00
IUUC-Ola-086376	Oryzias latipes	69.08	0.00e+00	1413.00
IUUC-Oga-088186	Otolemur garnettii	84.68	0.00e+00	1870.00
IUUC-Oar-089307	Ovis aries	85.05	0.00e+00	1895.00
IUUC-Ptr-090609	Pan troglodytes	84.39	0.00e+00	1864.00
IUUC-Pan-092905	Papio anubis	84.12	0.00e+00	1783.00
IUUC-Psi-093489	Pelodiscus sinensis	83.06	0.00e+00	1779.00
IUUC-Pma-094203	Petromyzon marinus	66.89	2.00e-57	214.00
IUUC-Pfo-096670	Poecilia formosa	68.98	0.00e+00	1461.00
IUUC-Pab-098418	Pongo abelii	84.11	0.00e+00	1857.00
IUUC-Pca-100889	Procavia capensis	72.47	0.00e+00	1514.00
IUUC-Pva-103144	Pteropus vampyrus	73.60	0.00e+00	1600.00
IUUC-Rno-105612	Rattus norvegicus	85.77	0.00e+00	1873.00
IUUC-Sha-107388	Sarcophilus harrisii	95.38	0.00e+00	2034.00
IUUC-Sar-113128	Sorex araneus	83.93	0.00e+00	1835.00
IUUC-Ssc-116117	Sus scrofa	84.88	0.00e+00	1894.00
IUUC-Tgu-116565	Taeniopygia guttata	82.17	0.00e+00	1761.00
IUUC-Tru-118591	Takifugu rubripes	67.42	0.00e+00	1416.00
IUUC-Tsy-119436	Tarsius syrichta	76.56	0.00e+00	1597.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.70	0.00e+00	1403.00
IUUC-Tbe-127714	Tupaia belangeri	73.68	0.00e+00	1317.00
IUUC-Ttr-129159	Tursiops truncatus	74.08	0.00e+00	1578.00
IUUC-Vpa-130716	Vicugna pacos	84.11	0.00e+00	1793.00
IUUC-Xtr-132947	Xenopus tropicalis	70.12	0.00e+00	1533.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence