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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064011
Ensembl Protein ID ENSMUSP00000106234.1
UniProt Accession A6PWY4; A2ASQ8; A4FUV0; Q504Z3; Q9CTV4; WDR76_MOUSE
Genbank Protein ID BAB31961.2; CAM19245.1; CAM19246.1; CAO78067.1; AAH94676.1; AAI17823.1
Protein Name WD repeat-containing protein 76
Genbank Nucleotide ID AK020004; AL928678; AL928678; AL928678; BC094676; BC117822
Gene Name Wdr76
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000027242.14 ENSMUST00000099473.9 ENSMUSP00000097072.3
ENSMUSG00000027242.14 ENSMUST00000110603.1 ENSMUSP00000106234.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-12 48.8 312 346
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf..sd..tllvsGsdDgtikvWDlrtg 33
           ++ ++++a+  s+  tl+++G+  g+i +WDl+++
   Q: 312  KGAISSVALhpSEvrTLVAAGAKSGQIGLWDLTQQ 346
           57899***998668799999************987 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
 Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Protein Sequence
(Fasta)
MSGSKAESEE KAGSKQCPLV QVNEYKENEH IAYTSLRPIQ ITTLRKTAKV YLYPFSLSNS 60
KLGLLKLSKS PVVNNSSKSV VHKKKDRKKT RRKVLTSKMK ALSSKADSLL LKSSVDAYTE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064011|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCTGAGCGC GGATCGCTTA AAGGGCTAGG GTGAGATTTG CGCGCCTTTC GAGCAAGTTT 60
CCCGCCTTCG ACATTTTCCA GAACTGGAAG GTCCTCCTGT CTGACAGTTG TTTCTTTTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064011|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0006974--P:cellular response to DNA damage stimulus
KEGG mmu:241627
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003441 Anas platyrhynchos 55.30 4.00e-153 534.00
IUUC-Aca-004241 Anolis carolinensis 57.66 1.00e-150 526.00
IUUC-Aly-005444 Arabidopsis lyrata 27.27 5.00e-25 109.00
IUUC-Ath-007550 Arabidopsis thaliana 27.36 8.00e-24 105.00
IUUC-Ago-007715 Ashbya gossypii 26.28 4.00e-21 96.30
IUUC-Acl-008370 Aspergillus clavatus 25.27 2.00e-26 114.00
IUUC-Afl-008586 Aspergillus flavus 26.67 9.00e-29 121.00
IUUC-Afu-008907 Aspergillus fumigatus 26.27 9.00e-28 118.00
IUUC-Ani-009415 Aspergillus nidulans 26.86 6.00e-26 112.00
IUUC-Ang-009597 Aspergillus niger 24.73 2.00e-08 54.30
IUUC-Aor-010197 Aspergillus oryzae 26.67 6.00e-29 122.00
IUUC-Ate-010280 Aspergillus terreus 26.37 1.00e-29 124.00
IUUC-Bgr-012236 Blumeria graminis 26.29 4.00e-27 115.00
IUUC-Bta-013059 Bos taurus 70.79 0.00e+00 843.00
IUUC-Bci-013796 Botrytis cinerea 27.41 9.00e-28 118.00
IUUC-Bdi-015040 Brachypodium distachyon 29.72 5.00e-21 95.50
IUUC-Bol-015202 Brassica oleracea 28.29 2.00e-22 100.00
IUUC-Bra-018032 Brassica rapa 26.73 6.00e-22 99.00
IUUC-Cja-019043 Callithrix jacchus 69.63 0.00e+00 821.00
IUUC-Cfa-021103 Canis familiaris 71.95 0.00e+00 863.00
IUUC-Cpo-021508 Cavia porcellus 70.16 0.00e+00 837.00
IUUC-Cre-022967 Chlamydomonas reinhardtii 30.52 3.00e-10 60.50
IUUC-Csa-023555 Chlorocebus sabaeus 71.37 0.00e+00 734.00
IUUC-Cho-024931 Choloepus hoffmanni 67.56 9.00e-79 288.00
IUUC-Cin-025651 Ciona intestinalis 31.26 3.00e-65 242.00
IUUC-Cgl-026604 Colletotrichum gloeosporioides 27.03 4.00e-29 122.00
IUUC-Cne-027093 Cryptococcus neoformans 26.03 6.00e-22 99.00
IUUC-Cme-027238 Cyanidioschyzon merolae 25.50 2.00e-20 94.40
IUUC-Dre-027441 Danio rerio 41.09 5.00e-96 345.00
IUUC-Dno-029575 Dasypus novemcinctus 71.96 0.00e+00 842.00
IUUC-Dor-030554 Dipodomys ordii 68.86 0.00e+00 649.00
IUUC-Dse-031299 Dothistroma septosporum 25.52 3.00e-28 119.00
IUUC-Ete-032716 Echinops telfairi 71.68 8.00e-92 331.00
IUUC-Eca-034027 Equus caballus 70.70 0.00e+00 701.00
IUUC-Eeu-035234 Erinaceus europaeus 78.21 1.00e-74 274.00
IUUC-Fca-035892 Felis catus 71.43 0.00e+00 858.00
IUUC-Fal-036986 Ficedula albicollis 54.27 1.00e-135 476.00
IUUC-Fox-037750 Fusarium oxysporum 27.30 1.00e-28 120.00
IUUC-Fso-038198 Fusarium solani 25.00 7.00e-23 102.00
IUUC-Gga-040479 Gallus gallus 52.73 2.00e-108 385.00
IUUC-Gac-042043 Gasterosteus aculeatus 44.65 4.00e-95 342.00
IUUC-Ggo-045290 Gorilla gorilla 71.22 0.00e+00 832.00
IUUC-Hsa-047021 Homo sapiens 70.91 0.00e+00 823.00
IUUC-Hvu-047193 Hordeum vulgare 29.25 1.00e-20 94.00
IUUC-Itr-047914 Ictidomys tridecemlineatus 73.40 0.00e+00 897.00
IUUC-Kpa-049275 Komagataella pastoris 23.77 9.00e-22 98.60
IUUC-Lch-049718 Latimeria chalumnae 53.99 4.00e-145 508.00
IUUC-Lpe-051708 Leersia perrieri 28.61 9.00e-17 81.60
IUUC-Loc-052565 Lepisosteus oculatus 47.54 1.00e-117 417.00
IUUC-Lma-053276 Leptosphaeria maculans 26.76 4.00e-28 120.00
IUUC-Laf-053970 Loxodonta africana 67.51 0.00e+00 793.00
IUUC-Mcc-054740 Macaca mulatta 72.08 0.00e+00 738.00
IUUC-Meu-056546 Macropus eugenii 62.24 2.00e-75 276.00
IUUC-Mtr-058451 Medicago truncatula 25.79 2.00e-30 127.00
IUUC-Mla-058906 Melampsora laricipopulina 24.87 5.00e-21 95.90
IUUC-Mga-059328 Meleagris gallopavo 50.23 1.00e-111 396.00
IUUC-Mvi-060555 Microbotryum violaceum 28.30 2.00e-23 104.00
IUUC-Mmr-061520 Microcebus murinus 71.20 0.00e+00 896.00
IUUC-Mdo-062812 Monodelphis domestica 57.00 0.00e+00 660.00
IUUC-Mpu-066486 Mustela putorius furo 71.43 0.00e+00 847.00
IUUC-Mlu-067721 Myotis lucifugus 68.74 0.00e+00 682.00
IUUC-Nfi-068314 Neosartorya fischeri 26.93 5.00e-27 115.00
IUUC-Ncr-068896 Neurospora crassa 25.89 6.00e-28 119.00
IUUC-Nle-069369 Nomascus leucogenys 71.07 0.00e+00 856.00
IUUC-Opr-070975 Ochotona princeps 69.52 0.00e+00 783.00
IUUC-Ont-072528 Oreochromis niloticus 44.14 1.00e-101 363.00
IUUC-Oan-072955 Ornithorhynchus anatinus 57.60 3.00e-136 478.00
IUUC-Ocu-074561 Oryctolagus cuniculus 72.24 0.00e+00 816.00
IUUC-Oba-074982 Oryza barthii 28.12 8.00e-21 95.50
IUUC-Ogl-077685 Oryza glaberrima 28.05 3.00e-22 99.80
IUUC-Ogu-078331 Oryza glumaepatula 28.05 2.00e-22 100.00
IUUC-Oin-079507 Oryza indica 28.23 7.00e-22 99.00
IUUC-Ome-081816 Oryza meridionalis 27.33 7.00e-21 95.10
IUUC-Oni-082051 Oryza nivara 28.05 4.00e-22 99.40
IUUC-Opu-083372 Oryza punctata 28.36 2.00e-22 100.00
IUUC-Oru-084578 Oryza rufipogon 28.05 2.00e-22 100.00
IUUC-Osa-086177 Oryza sativa 28.05 2.00e-22 100.00
IUUC-Ola-087208 Oryzias latipes 42.09 9.00e-95 340.00
IUUC-Olu-087680 Ostreococcus lucimarinus 29.08 3.00e-33 136.00
IUUC-Oga-088104 Otolemur garnettii 71.82 0.00e+00 850.00
IUUC-Oar-090157 Ovis aries 70.68 0.00e+00 851.00
IUUC-Ptr-091615 Pan troglodytes 70.59 0.00e+00 821.00
IUUC-Pan-092212 Papio anubis 69.16 0.00e+00 792.00
IUUC-Psi-092950 Pelodiscus sinensis 61.62 2.00e-169 589.00
IUUC-Pma-094625 Petromyzon marinus 38.70 8.00e-33 134.00
IUUC-Pno-094824 Phaeosphaeria nodorum 25.49 3.00e-32 133.00
IUUC-Pfo-096922 Poecilia formosa 42.86 1.00e-103 370.00
IUUC-Pab-097591 Pongo abelii 71.54 0.00e+00 841.00
IUUC-Pop-099337 Populus trichocarpa 24.32 1.00e-29 124.00
IUUC-Pca-101025 Procavia capensis 57.54 6.00e-179 620.00
IUUC-Ppe-101256 Prunus persica 26.57 3.00e-16 80.10
IUUC-Pva-102453 Pteropus vampyrus 65.06 0.00e+00 733.00
IUUC-Pgr-103436 Puccinia graminis 24.74 1.00e-22 101.00
IUUC-Ptt-103899 Puccinia triticina 29.90 6.00e-21 95.90
IUUC-Pte-104258 Pyrenophora teres 27.01 3.00e-30 126.00
IUUC-Pyt-104625 Pyrenophora triticirepentis 27.27 6.00e-31 128.00
IUUC-Rno-104843 Rattus norvegicus 85.21 0.00e+00 1013.00
IUUC-Sce-106189 Saccharomyces cerevisiae 23.38 3.00e-22 99.80
IUUC-Sha-106672 Sarcophilus harrisii 61.13 0.00e+00 655.00
IUUC-Sit-109704 Setaria italica 28.53 6.00e-25 108.00
IUUC-Sly-111853 Solanum lycopersicum 23.84 3.00e-23 103.00
IUUC-Stu-112482 Solanum tuberosum 23.94 6.00e-21 95.50
IUUC-Sar-113537 Sorex araneus 52.59 1.00e-87 317.00
IUUC-Sbi-114517 Sorghum bicolor 27.48 4.00e-18 86.30
IUUC-Sre-114960 Sporisorium reilianum 26.03 4.00e-10 60.10
IUUC-Ssc-115568 Sus scrofa 71.36 0.00e+00 871.00
IUUC-Tgu-117276 Taeniopygia guttata 49.68 5.00e-124 437.00
IUUC-Tru-117559 Takifugu rubripes 52.80 6.00e-36 142.00
IUUC-Tsy-119234 Tarsius syrichta 53.58 5.00e-162 564.00
IUUC-Tni-120358 Tetraodon nigroviridis 41.98 4.00e-93 335.00
IUUC-Tca-121273 Theobroma cacao 25.47 5.00e-22 99.40
IUUC-Tre-121932 Trichoderma reesei 27.22 2.00e-29 124.00
IUUC-Tvi-122567 Trichoderma virens 28.49 2.00e-33 136.00
IUUC-Tae-123506 Triticum aestivum 28.66 1.00e-18 87.40
IUUC-Tme-126958 Tuber melanosporum 26.84 2.00e-17 83.60
IUUC-Tbe-127425 Tupaia belangeri 75.29 0.00e+00 683.00
IUUC-Ttr-129123 Tursiops truncatus 63.10 0.00e+00 707.00
IUUC-Uma-129495 Ustilago maydis 34.27 2.00e-11 64.30
IUUC-Vda-129981 Verticillium dahliae 27.62 7.00e-30 125.00
IUUC-Vpa-130437 Vicugna pacos 65.24 0.00e+00 749.00
IUUC-Xtr-132670 Xenopus tropicalis 54.76 5.00e-133 468.00
IUUC-Xma-133375 Xiphophorus maculatus 44.26 2.00e-104 372.00
IUUC-Yli-134341 Yarrowia lipolytica 26.38 7.00e-24 105.00
IUUC-Zma-135413 Zea mays 29.36 4.00e-24 105.00
Created Date 25-Jun-2017

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