iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125113

Ensembl Protein ID

TRIAE_CS42_4DS_TGACv1_362000_AA1175530.1

UniProt Accession

W5EQM1; W5EQM1_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_4DS_TGACv1_362000_AA1175530	TRIAE_CS42_4DS_TGACv1_362000_AA1175530.1	TRIAE_CS42_4DS_TGACv1_362000_AA1175530.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.80e-172	576.3	437	925

Active Site

Position(s)	Description	Evidence
618	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLf 64
           YD Qi ++G++ q+kl++ak+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLf
   Q: 437  YDAQISVFGSKLQNKLEQAKIFMVGSGALGCEFLKNLALMGIscsqnGKLTVTDDDVIEKSNLSRQFLF 505
           ********************************************************************* PP
   S: 65   raedvgksKAevaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlc 130
           r++++g++K+ vaa a+  +np+ +vea +++ ++++e+++   F +++d Vv+aldn+ ar++++++c
   Q: 506  RDWNIGQPKSTVAATAAMAINPKLHVEALQNRASPETENVFndaFWENLDAVVNALDNVTARMYIDSRC 574
           ***************************************99**************************** PP
   S: 131  lnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa......... 190
           ++ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa         
   Q: 575  VYFQKPLLESGTLGAKCNAQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsefeglle 643
           *************************************************************99999999 PP
   S: 191  ...vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikql 256
                +n +l++ +  +  +     ++ ++ +++v + l + + e+f+++i++a+ +f+ +++n +kql
   Q: 644  ktpTEVNGFLSNPSVYVAAARTAGDAQARDQLERVIECLHGDKCETFQDCITWARLKFEDYFSNRVKQL 712
           99988888888888888888888888999999999999999**************************** PP
   S: 257  lksfecdivtkskspfwv................................................... 274
           +  f+ d +t+s++pfw+                                                   
   Q: 713  TYTFPEDSMTSSGAPFWSapkrfprplefsstdpsqlnfilaasilraetfgipipdwaktrnkvaaea 781
           **********************************************************99988888888 PP
   S: 275  ........sfcsnaealqvpekvekdeevvkasap..lylllralerfekk..kgrkpgelsfekddds 331
                     +++  ++ ++ek+++   ++ ++ +  ++ l+++le+ +k+  +g  ++ ++fekddd 
   Q: 782  vdkvivpeFQPKQGVKIVTDEKATSISSASVDD-AgvIEELITKLEQISKTlpPGFHMNPIQFEKDDDT 849
           888666632233334444555555555544333.369************976689************** PP
   S: 332  ..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplk 396
             ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  k e ++
   Q: 850  nfHMDVIAGFANMRARNYSIPE-VDKLKAKFIAGRIIPAIATATAMATGLVCLELYKVLAGghKVEDYR 917
           **********************.**************************************999***** PP
   S: 397  nfflfdae 404
           n+f ++a+
   Q: 918  NTFANLAI 925
           ***99876 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MLPRKREIVA SEVENLQKKT RPAAADDAMA RPTEIDEDLH SRQLAVYGRE TMKRLFASNV 60
LVSGLQGLGA EIAKNLVLAG VKSVTLHDDG NVELWDLSSN FFLSEKDVGQ NRAQACVLKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTTCCTCG TATAACCCTA GAGGCTCTCC TCGCACTCCA CGAATCCTTG GTGAGCTCCG 60
TGCTTCCGCC CAATCCCCCC TCTCCCCGAT CCTCCCTCCC CCTCGCTCTC CCCGCCTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	100.00	0.00e+00	1963.00
IUUC-Aml-001311	Ailuropoda melanoleuca	45.90	0.00e+00	894.00
IUUC-Atr-002684	Amborella trichopoda	77.34	0.00e+00	1645.00
IUUC-Aca-004620	Anolis carolinensis	44.70	0.00e+00	876.00
IUUC-Aly-005418	Arabidopsis lyrata	78.22	0.00e+00	1668.00
IUUC-Ath-006891	Arabidopsis thaliana	78.20	0.00e+00	1665.00
IUUC-Afl-008455	Aspergillus flavus	46.21	0.00e+00	806.00
IUUC-Aor-010007	Aspergillus oryzae	46.21	0.00e+00	805.00
IUUC-Ate-010466	Aspergillus terreus	46.67	0.00e+00	860.00
IUUC-Ame-010933	Astyanax mexicanus	45.42	0.00e+00	846.00
IUUC-Bta-012767	Bos taurus	45.93	0.00e+00	901.00
IUUC-Bci-013721	Botrytis cinerea	45.45	0.00e+00	803.00
IUUC-Bdi-014843	Brachypodium distachyon	93.51	0.00e+00	1883.00
IUUC-Bol-015880	Brassica oleracea	78.32	0.00e+00	1666.00
IUUC-Bra-017252	Brassica rapa	78.71	0.00e+00	1669.00
IUUC-Cja-019152	Callithrix jacchus	46.11	0.00e+00	897.00
IUUC-Cfa-020622	Canis familiaris	44.12	0.00e+00	844.00
IUUC-Cpo-022526	Cavia porcellus	46.12	0.00e+00	888.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	60.65	0.00e+00	1186.00
IUUC-Csa-023780	Chlorocebus sabaeus	46.16	0.00e+00	901.00
IUUC-Cin-025790	Ciona intestinalis	44.19	0.00e+00	861.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	47.58	0.00e+00	885.00
IUUC-Cne-026960	Cryptococcus neoformans	44.38	0.00e+00	844.00
IUUC-Dre-028149	Danio rerio	46.93	0.00e+00	874.00
IUUC-Dno-028884	Dasypus novemcinctus	46.30	0.00e+00	893.00
IUUC-Dor-030229	Dipodomys ordii	43.88	0.00e+00	842.00
IUUC-Ete-033124	Echinops telfairi	38.93	2.00e-130	461.00
IUUC-Eca-033330	Equus caballus	45.73	0.00e+00	893.00
IUUC-Fca-036255	Felis catus	45.35	0.00e+00	885.00
IUUC-Fox-038007	Fusarium oxysporum	47.16	4.00e-136	478.00
IUUC-Fso-038339	Fusarium solani	46.93	0.00e+00	840.00
IUUC-Gmo-039338	Gadus morhua	44.25	0.00e+00	823.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.64	0.00e+00	837.00
IUUC-Gma-043165	Glycine max	81.19	0.00e+00	1701.00
IUUC-Ggo-045336	Gorilla gorilla	45.93	0.00e+00	881.00
IUUC-Hsa-045982	Homo sapiens	45.97	0.00e+00	880.00
IUUC-Hvu-047418	Hordeum vulgare	97.51	0.00e+00	1980.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	45.78	0.00e+00	893.00
IUUC-Lch-050371	Latimeria chalumnae	44.96	0.00e+00	887.00
IUUC-Loc-052936	Lepisosteus oculatus	47.05	0.00e+00	888.00
IUUC-Laf-053948	Loxodonta africana	46.64	0.00e+00	874.00
IUUC-Mcc-055843	Macaca mulatta	45.93	0.00e+00	897.00
IUUC-Meu-056258	Macropus eugenii	46.12	0.00e+00	889.00
IUUC-Mtr-058572	Medicago truncatula	80.40	0.00e+00	1640.00
IUUC-Mla-059176	Melampsora laricipopulina	46.65	0.00e+00	866.00
IUUC-Mmr-061405	Microcebus murinus	44.78	0.00e+00	853.00
IUUC-Mdo-062032	Monodelphis domestica	44.87	0.00e+00	866.00
IUUC-Mmu-063721	Mus musculus	45.47	0.00e+00	886.00
IUUC-Mac-065505	Musa acuminata	81.35	0.00e+00	1702.00
IUUC-Mpu-066409	Mustela putorius furo	45.97	0.00e+00	899.00
IUUC-Mlu-067217	Myotis lucifugus	46.21	0.00e+00	885.00
IUUC-Nle-070072	Nomascus leucogenys	43.16	0.00e+00	803.00
IUUC-Opr-070715	Ochotona princeps	36.05	4.00e-157	549.00
IUUC-Ont-071671	Oreochromis niloticus	45.75	0.00e+00	874.00
IUUC-Ocu-074544	Oryctolagus cuniculus	46.02	0.00e+00	902.00
IUUC-Oba-075120	Oryza barthii	90.28	0.00e+00	1830.00
IUUC-Obr-076557	Oryza brachyantha	90.73	0.00e+00	1849.00
IUUC-Ogl-077887	Oryza glaberrima	90.28	0.00e+00	1833.00
IUUC-Oin-079370	Oryza indica	87.72	0.00e+00	1812.00
IUUC-Ome-081942	Oryza meridionalis	90.57	0.00e+00	1838.00
IUUC-Oni-082365	Oryza nivara	90.57	0.00e+00	1837.00
IUUC-Opu-083977	Oryza punctata	90.54	0.00e+00	1835.00
IUUC-Osa-085949	Oryza sativa	90.28	0.00e+00	1865.00
IUUC-Ola-087002	Oryzias latipes	46.35	0.00e+00	884.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.98	0.00e+00	1133.00
IUUC-Oga-088594	Otolemur garnettii	46.15	0.00e+00	877.00
IUUC-Oar-090068	Ovis aries	45.93	0.00e+00	895.00
IUUC-Pan-092114	Papio anubis	46.16	0.00e+00	898.00
IUUC-Ppa-095227	Physcomitrella patens	71.44	0.00e+00	1550.00
IUUC-Pfo-097184	Poecilia formosa	45.35	0.00e+00	866.00
IUUC-Pab-097861	Pongo abelii	46.07	0.00e+00	869.00
IUUC-Pop-098934	Populus trichocarpa	78.55	0.00e+00	1660.00
IUUC-Pca-100347	Procavia capensis	43.40	0.00e+00	712.00
IUUC-Ppe-102012	Prunus persica	79.62	0.00e+00	1685.00
IUUC-Pva-102584	Pteropus vampyrus	45.97	0.00e+00	913.00
IUUC-Pgr-103336	Puccinia graminis	45.77	0.00e+00	833.00
IUUC-Ptt-103939	Puccinia triticina	46.41	0.00e+00	830.00
IUUC-Rno-105462	Rattus norvegicus	45.57	0.00e+00	869.00
IUUC-Sha-107142	Sarcophilus harrisii	46.00	0.00e+00	888.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	44.69	0.00e+00	808.00
IUUC-Smo-108912	Selaginella moellendorffii	72.20	0.00e+00	1527.00
IUUC-Sit-110281	Setaria italica	90.23	0.00e+00	1870.00
IUUC-Sly-111237	Solanum lycopersicum	79.43	0.00e+00	1623.00
IUUC-Stu-112001	Solanum tuberosum	79.63	0.00e+00	1630.00
IUUC-Sar-113737	Sorex araneus	46.36	0.00e+00	885.00
IUUC-Sbi-114089	Sorghum bicolor	90.79	0.00e+00	1881.00
IUUC-Sre-115148	Sporisorium reilianum	45.54	0.00e+00	816.00
IUUC-Ssc-115777	Sus scrofa	45.68	0.00e+00	886.00
IUUC-Tru-118742	Takifugu rubripes	46.43	0.00e+00	833.00
IUUC-Tni-120401	Tetraodon nigroviridis	47.00	0.00e+00	842.00
IUUC-Tca-121436	Theobroma cacao	80.45	0.00e+00	1677.00
IUUC-Tvi-122259	Trichoderma virens	46.51	0.00e+00	842.00
IUUC-Tur-126189	Triticum urartu	99.11	0.00e+00	1946.00
IUUC-Tbe-127587	Tupaia belangeri	41.28	2.00e-139	490.00
IUUC-Ttr-128331	Tursiops truncatus	45.87	0.00e+00	880.00
IUUC-Uma-129387	Ustilago maydis	45.13	0.00e+00	821.00
IUUC-Vda-129977	Verticillium dahliae	46.65	0.00e+00	823.00
IUUC-Vvi-130857	Vitis vinifera	81.93	0.00e+00	1706.00
IUUC-Xma-133805	Xiphophorus maculatus	45.15	0.00e+00	844.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence