iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089853

Ensembl Protein ID

ENSOARP00000020697.1

UniProt Accession

W5QD99; W5QD99_SHEEP

Genbank Protein ID

ENSOARP00000020697

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01000669

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000019268.1	ENSOART00000020982.1	ENSOARP00000020697.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.20e-80	268.5	41	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+ +l++++++++ e  +
   Q: 41   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTADLTDSFGWTSDE--E 127
           9*****************************777777665543332234458899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+++e+fldl+++
   Q: 128  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNVSEKQEDFLDLTVA 190
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c ++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 191  VKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGNCGRLVKAAKSAKLRKLPPFLTISLLRFNFDFVKCERYKETSCYTFPLRINLKP 274
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  ++ YeL++v++H+G++ +GHY++y+k+                                                   
   Q: 275  FCEQSELDDL-EYMYELFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqedkskpdvnlediqnkeeiddplmilkaillqeesnlipvd 362
           ****999987.9***************************************************************************** PP
   S: 302  .............................................................................ekgk....Wllf 309
                                                                                        ++g     W+ +
   Q: 363  qlgqkllkkigiswnkkyrkqygplrkflqlhsqifllssdestvrllkdsslqvesdiqrndqrlfktltseslklNDGPscphWFDI 451
           **********************************************************999999999999988877633336678**** PP
   S: 310  dDskVtevkeeevleetg..staYvlfYkr 337
           +Ds+V+++ke++++++ +  ++aY+lfY++
   Q: 452  NDSRVQPIKEKDIEQQFQgkESAYMLFYRK 481
           ***************9889*********98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MFGDLFEEDY SSVSNNNGKG KRLKTKALEP PAPREFTNLS GIRNQGGTCY LNSLLQTLHF 60
TPEFREALFS LGPEELGSLE DKDKPDAKVR IIPLQLQRLF AQLLLLDQEA ASTADLTDSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGGAGATG CCAGAAGAGT CCAAAAAAAA AAAAAAAAAA CCTATCAAAG TAGACCACCA 60
AGCATGCTCA AGCGGGCAAA AGAGCATGAT TTTGAGGTAT TTTGGGTATG AGGGTCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	84.20	0.00e+00	1939.00
IUUC-Apl-004105	Anas platyrhynchos	63.66	0.00e+00	1532.00
IUUC-Aca-004715	Anolis carolinensis	62.06	0.00e+00	1479.00
IUUC-Ame-011073	Astyanax mexicanus	47.63	0.00e+00	1031.00
IUUC-Bta-012487	Bos taurus	96.52	0.00e+00	2341.00
IUUC-Cja-018937	Callithrix jacchus	83.62	0.00e+00	2039.00
IUUC-Cfa-020645	Canis familiaris	80.51	0.00e+00	1261.00
IUUC-Cpo-022160	Cavia porcellus	77.74	0.00e+00	1900.00
IUUC-Csa-023078	Chlorocebus sabaeus	83.20	0.00e+00	2071.00
IUUC-Cho-025013	Choloepus hoffmanni	65.51	0.00e+00	811.00
IUUC-Csv-026193	Ciona savignyi	56.28	1.00e-59	222.00
IUUC-Dre-027416	Danio rerio	48.64	0.00e+00	1144.00
IUUC-Dno-029639	Dasypus novemcinctus	80.19	0.00e+00	1659.00
IUUC-Dor-030624	Dipodomys ordii	90.70	3.00e-153	536.00
IUUC-Ete-032626	Echinops telfairi	62.84	0.00e+00	737.00
IUUC-Eca-034208	Equus caballus	87.24	0.00e+00	2133.00
IUUC-Eeu-035340	Erinaceus europaeus	51.82	1.00e-103	371.00
IUUC-Fca-035886	Felis catus	74.39	0.00e+00	790.00
IUUC-Fal-036925	Ficedula albicollis	63.03	0.00e+00	1423.00
IUUC-Gmo-038597	Gadus morhua	45.38	0.00e+00	885.00
IUUC-Gga-041171	Gallus gallus	62.96	0.00e+00	1504.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.49	0.00e+00	962.00
IUUC-Ggo-045069	Gorilla gorilla	82.01	0.00e+00	1864.00
IUUC-Hsa-046715	Homo sapiens	84.09	0.00e+00	2067.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	79.39	0.00e+00	1907.00
IUUC-Lch-050182	Latimeria chalumnae	52.45	0.00e+00	1167.00
IUUC-Loc-052705	Lepisosteus oculatus	53.55	0.00e+00	1262.00
IUUC-Laf-054132	Loxodonta africana	82.41	0.00e+00	2033.00
IUUC-Mcc-055734	Macaca mulatta	83.84	0.00e+00	2078.00
IUUC-Meu-056135	Macropus eugenii	48.25	1.00e-119	424.00
IUUC-Mga-060092	Meleagris gallopavo	62.65	0.00e+00	1479.00
IUUC-Mmr-061546	Microcebus murinus	80.89	0.00e+00	1959.00
IUUC-Mdo-061935	Monodelphis domestica	64.16	0.00e+00	1520.00
IUUC-Mmu-063630	Mus musculus	78.45	0.00e+00	1935.00
IUUC-Mpu-066579	Mustela putorius furo	82.08	0.00e+00	2033.00
IUUC-Mlu-068034	Myotis lucifugus	86.36	0.00e+00	2036.00
IUUC-Nle-069082	Nomascus leucogenys	81.33	0.00e+00	1697.00
IUUC-Opr-070953	Ochotona princeps	69.72	0.00e+00	956.00
IUUC-Ont-072435	Oreochromis niloticus	47.69	0.00e+00	1091.00
IUUC-Oan-073339	Ornithorhynchus anatinus	67.06	0.00e+00	1570.00
IUUC-Ocu-073760	Oryctolagus cuniculus	80.13	0.00e+00	1962.00
IUUC-Ola-087015	Oryzias latipes	47.09	0.00e+00	929.00
IUUC-Oga-088960	Otolemur garnettii	82.81	0.00e+00	2024.00
IUUC-Ptr-091093	Pan troglodytes	83.84	0.00e+00	2059.00
IUUC-Pan-091962	Papio anubis	82.24	0.00e+00	2048.00
IUUC-Psi-093691	Pelodiscus sinensis	66.08	0.00e+00	1589.00
IUUC-Pma-094428	Petromyzon marinus	66.19	7.00e-93	333.00
IUUC-Pfo-096983	Poecilia formosa	48.32	0.00e+00	1030.00
IUUC-Pab-097860	Pongo abelii	83.15	0.00e+00	1907.00
IUUC-Pca-100514	Procavia capensis	78.65	0.00e+00	655.00
IUUC-Pva-102771	Pteropus vampyrus	83.66	0.00e+00	1907.00
IUUC-Rno-105405	Rattus norvegicus	77.64	0.00e+00	1894.00
IUUC-Sha-107376	Sarcophilus harrisii	65.25	0.00e+00	1486.00
IUUC-Ssc-115819	Sus scrofa	83.26	0.00e+00	1467.00
IUUC-Tgu-117262	Taeniopygia guttata	62.05	0.00e+00	1483.00
IUUC-Tru-117601	Takifugu rubripes	47.64	0.00e+00	1093.00
IUUC-Tsy-118996	Tarsius syrichta	72.99	0.00e+00	1593.00
IUUC-Tni-120682	Tetraodon nigroviridis	44.02	0.00e+00	879.00
IUUC-Tbe-127616	Tupaia belangeri	64.03	0.00e+00	1101.00
IUUC-Ttr-129075	Tursiops truncatus	86.32	0.00e+00	1997.00
IUUC-Vpa-130108	Vicugna pacos	86.48	0.00e+00	1873.00
IUUC-Xtr-132623	Xenopus tropicalis	52.12	0.00e+00	1173.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence