iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017388.1	ENSSHAT00000020671.1	ENSSHAP00000020508.1
ENSSHAG00000017388.1	ENSSHAT00000020672.1	ENSSHAP00000020509.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.10e-07	31.9	103	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l+ ++  GFd++ +++aLr++ n+++eaA+e++ 
   Q: 103  NRQMLQDMQIAGFDEDMVIRALRQTnNKSIEAAIEFIS 140
           569*********************99*********975 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MKRGEKPEGY RQMRPKTFPA SNYTGSSRQM LQEIRESLRN LPKPSDAAKA EHSMSKMTTE 60
DPRQGRNPPK FVTYHKALQE IRNSLLPFAN EASSSTRSAS EVNRQMLQDM QIAGFDEDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGACTAGA TTCAATCCTC TTTTCATTGT AATCAATTAT AAATGTAATT TTTCGTTATT 60
TTTAGAGTTG AACCATTTCA GCCGGGAAGA ACCCGTCAGA CCTCAAGACT TTATGAAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

KEGG

shr:100931242

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	89.16	0.00e+00	1878.00
IUUC-Apl-003278	Anas platyrhynchos	84.37	0.00e+00	1811.00
IUUC-Aca-005319	Anolis carolinensis	83.11	0.00e+00	1751.00
IUUC-Ame-011324	Astyanax mexicanus	85.28	0.00e+00	943.00
IUUC-Bta-013438	Bos taurus	88.55	0.00e+00	1832.00
IUUC-Cel-018517	Caenorhabditis elegans	50.54	3.00e-129	456.00
IUUC-Cja-019072	Callithrix jacchus	88.28	0.00e+00	1890.00
IUUC-Cfa-021267	Canis familiaris	88.90	0.00e+00	1883.00
IUUC-Cpo-021496	Cavia porcellus	85.32	0.00e+00	1568.00
IUUC-Csa-023255	Chlorocebus sabaeus	89.25	0.00e+00	1877.00
IUUC-Cho-024461	Choloepus hoffmanni	96.79	0.00e+00	779.00
IUUC-Cin-025264	Ciona intestinalis	65.58	6.00e-141	493.00
IUUC-Dre-028034	Danio rerio	85.14	0.00e+00	939.00
IUUC-Dno-029888	Dasypus novemcinctus	86.96	0.00e+00	1887.00
IUUC-Dor-030144	Dipodomys ordii	79.21	0.00e+00	1597.00
IUUC-Dme-031656	Drosophila melanogaster	73.43	0.00e+00	655.00
IUUC-Ete-032813	Echinops telfairi	91.43	0.00e+00	1202.00
IUUC-Eca-033781	Equus caballus	88.99	0.00e+00	1848.00
IUUC-Eeu-035007	Erinaceus europaeus	87.22	0.00e+00	1856.00
IUUC-Fca-036142	Felis catus	83.52	0.00e+00	1766.00
IUUC-Fal-036626	Ficedula albicollis	84.46	0.00e+00	1826.00
IUUC-Gmo-038688	Gadus morhua	86.46	0.00e+00	783.00
IUUC-Gga-040553	Gallus gallus	84.97	0.00e+00	1808.00
IUUC-Gac-042031	Gasterosteus aculeatus	64.19	0.00e+00	1272.00
IUUC-Ggo-045242	Gorilla gorilla	89.44	0.00e+00	1885.00
IUUC-Hsa-046081	Homo sapiens	89.25	0.00e+00	1878.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	89.99	0.00e+00	1613.00
IUUC-Lch-049425	Latimeria chalumnae	78.75	0.00e+00	1691.00
IUUC-Loc-052418	Lepisosteus oculatus	67.21	0.00e+00	1369.00
IUUC-Laf-053710	Loxodonta africana	88.20	0.00e+00	1865.00
IUUC-Mcc-055079	Macaca mulatta	89.25	0.00e+00	1872.00
IUUC-Mga-059713	Meleagris gallopavo	84.12	0.00e+00	1813.00
IUUC-Mmr-061728	Microcebus murinus	89.52	0.00e+00	1896.00
IUUC-Mdo-061942	Monodelphis domestica	96.57	0.00e+00	2011.00
IUUC-Mmu-063504	Mus musculus	86.70	0.00e+00	1798.00
IUUC-Mpu-066034	Mustela putorius furo	88.46	0.00e+00	1852.00
IUUC-Mlu-067986	Myotis lucifugus	87.49	0.00e+00	1851.00
IUUC-Nle-069202	Nomascus leucogenys	89.07	0.00e+00	1876.00
IUUC-Opr-070801	Ochotona princeps	92.40	0.00e+00	1256.00
IUUC-Ont-072487	Oreochromis niloticus	62.47	0.00e+00	1221.00
IUUC-Oan-073128	Ornithorhynchus anatinus	87.89	0.00e+00	1629.00
IUUC-Ocu-073998	Oryctolagus cuniculus	91.73	0.00e+00	1381.00
IUUC-Ola-086858	Oryzias latipes	83.27	0.00e+00	894.00
IUUC-Oga-088874	Otolemur garnettii	87.32	0.00e+00	1815.00
IUUC-Oar-089236	Ovis aries	88.38	0.00e+00	1830.00
IUUC-Ptr-091425	Pan troglodytes	89.43	0.00e+00	1882.00
IUUC-Pan-091851	Papio anubis	89.44	0.00e+00	1880.00
IUUC-Psi-093825	Pelodiscus sinensis	87.02	0.00e+00	1518.00
IUUC-Pfo-096326	Poecilia formosa	61.66	0.00e+00	1199.00
IUUC-Pab-097815	Pongo abelii	89.34	0.00e+00	1881.00
IUUC-Pva-102836	Pteropus vampyrus	87.40	0.00e+00	1775.00
IUUC-Ptt-103762	Puccinia triticina	37.93	4.00e-93	336.00
IUUC-Rno-106053	Rattus norvegicus	87.14	0.00e+00	1832.00
IUUC-Sar-113649	Sorex araneus	88.16	0.00e+00	1465.00
IUUC-Ssc-115486	Sus scrofa	95.95	0.00e+00	847.00
IUUC-Tgu-116903	Taeniopygia guttata	84.64	0.00e+00	1813.00
IUUC-Tru-118760	Takifugu rubripes	64.44	0.00e+00	1298.00
IUUC-Tsy-119361	Tarsius syrichta	88.51	0.00e+00	1618.00
IUUC-Tni-120058	Tetraodon nigroviridis	61.61	0.00e+00	1151.00
IUUC-Tbe-127681	Tupaia belangeri	90.36	0.00e+00	1479.00
IUUC-Ttr-128652	Tursiops truncatus	88.41	0.00e+00	1550.00
IUUC-Vpa-130538	Vicugna pacos	88.28	0.00e+00	1840.00
IUUC-Xtr-132895	Xenopus tropicalis	71.78	0.00e+00	1285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence