iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036317

Ensembl Protein ID

ENSFCAP00000019517.1

UniProt Accession

M3WYS7; M3WYS7_FELCA

Genbank Protein ID

ENSFCAP00000019517

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02013038

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000027677.1	ENSFCAT00000026694.1	ENSFCAP00000019517.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	95.96	5.00e-107	384.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

LPTPAMFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCCACCC CGGCCATGCT CNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	93.33	6.00e-104	369.00
IUUC-Apl-003607	Anas platyrhynchos	79.56	3.00e-92	330.00
IUUC-Aca-005063	Anolis carolinensis	81.08	3.00e-99	353.00
IUUC-Ath-006990	Arabidopsis thaliana	33.78	1.20e-02	35.40
IUUC-Ame-010859	Astyanax mexicanus	54.35	3.00e-66	244.00
IUUC-Bta-012817	Bos taurus	90.31	2.00e-106	378.00
IUUC-Bra-017963	Brassica rapa	30.00	7.20e-02	32.00
IUUC-Cja-019605	Callithrix jacchus	95.07	3.00e-110	390.00
IUUC-Cfa-021231	Canis familiaris	94.22	1.00e-105	375.00
IUUC-Cpo-022003	Cavia porcellus	89.04	6.00e-104	369.00
IUUC-Csa-023511	Chlorocebus sabaeus	95.96	2.00e-108	384.00
IUUC-Dre-028536	Danio rerio	56.03	9.00e-69	252.00
IUUC-Dno-029003	Dasypus novemcinctus	90.67	1.00e-106	378.00
IUUC-Eca-034205	Equus caballus	83.80	4.00e-68	249.00
IUUC-Gmo-038777	Gadus morhua	63.89	7.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	81.61	1.00e-92	332.00
IUUC-Gac-041837	Gasterosteus aculeatus	56.59	3.00e-64	237.00
IUUC-Ggo-045620	Gorilla gorilla	95.96	2.00e-108	384.00
IUUC-Hsa-046909	Homo sapiens	95.96	2.00e-108	384.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	89.66	2.00e-108	384.00
IUUC-Lch-049510	Latimeria chalumnae	67.12	8.00e-81	292.00
IUUC-Loc-052863	Lepisosteus oculatus	60.00	1.00e-74	272.00
IUUC-Laf-054136	Loxodonta africana	90.79	7.00e-106	376.00
IUUC-Mcc-055383	Macaca mulatta	95.96	2.00e-108	384.00
IUUC-Meu-056153	Macropus eugenii	86.61	2.00e-107	381.00
IUUC-Mmr-061185	Microcebus murinus	92.92	1.00e-103	368.00
IUUC-Mdo-061819	Monodelphis domestica	86.55	8.00e-108	382.00
IUUC-Mmu-064231	Mus musculus	94.17	5.00e-115	406.00
IUUC-Mpu-066691	Mustela putorius furo	94.67	1.00e-105	375.00
IUUC-Mlu-067673	Myotis lucifugus	94.20	2.00e-113	400.00
IUUC-Ont-072406	Oreochromis niloticus	52.84	3.00e-65	240.00
IUUC-Oan-073249	Ornithorhynchus anatinus	74.22	6.00e-91	326.00
IUUC-Ocu-074935	Oryctolagus cuniculus	88.24	1.00e-31	127.00
IUUC-Ola-087373	Oryzias latipes	47.57	2.00e-48	184.00
IUUC-Oga-088041	Otolemur garnettii	93.33	3.00e-106	377.00
IUUC-Oar-089646	Ovis aries	88.21	1.00e-99	355.00
IUUC-Ptr-091502	Pan troglodytes	95.96	2.00e-108	384.00
IUUC-Pan-091934	Papio anubis	95.96	2.00e-108	384.00
IUUC-Pfo-096412	Poecilia formosa	40.81	4.00e-46	177.00
IUUC-Pab-098554	Pongo abelii	95.96	2.00e-108	384.00
IUUC-Rno-105874	Rattus norvegicus	93.72	8.00e-114	402.00
IUUC-Sha-107151	Sarcophilus harrisii	85.40	3.00e-107	380.00
IUUC-Ssc-115722	Sus scrofa	81.98	6.00e-65	239.00
IUUC-Tgu-117151	Taeniopygia guttata	80.27	7.00e-92	329.00
IUUC-Tru-118428	Takifugu rubripes	52.40	8.00e-65	239.00
IUUC-Tni-120590	Tetraodon nigroviridis	52.40	2.00e-63	234.00
IUUC-Ttr-129065	Tursiops truncatus	90.75	9.00e-107	379.00
IUUC-Xtr-132167	Xenopus tropicalis	64.44	1.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence