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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106302
Ensembl Protein ID YPR154W
UniProt Accession Q06449; D6W4F0; PIN3_YEAST
Genbank Protein ID AAB68051.1; AAT93008.1; DAA11566.1
Protein Name [PSI+] inducibility protein 3; LAS seventeen-binding protein 2
Genbank Nucleotide ID U28371; AY692989; BK006949
Gene Name PIN3; LSB2; YPR154W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YPR154W YPR154W YPR154W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMUniProt
PHOSIDABioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.20e-15 55.6 55 110
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           s+e+v++ly++++q+d++L lk Gd+v+++  e+ + +W kg    +g+ G+fP+n+v+ 
   Q: 55   SLEYVEALYQFDPQQDGDLGLKPGDKVQLL--EKLSPEWYKG--SCNGRTGIFPANYVKP 110
           5789**************************..999*******..9*************96 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.
 Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.
Protein Sequence
(Fasta)
MSASLINRSL TNIRTELDFL KGSNVISNDV YDQINKSLPA KWDPANAPRN ASPASLEYVE 60
ALYQFDPQQD GDLGLKPGDK VQLLEKLSPE WYKGSCNGRT GIFPANYVKP AFSGSNGPSN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106302|UBD,SH3|Saccharomyces cerevisiae
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Nucleotide Sequence
(Fasta)
ATGTCTGCTT CATTGATTAA TCGTTCCTTA ACAAACATTA GGACAGAACT GGATTTTCTA 60
AAAGGGTCAA ATGTCATTTC AAATGACGTT TACGATCAAA TAAATAAGAG CTTGCCGGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106302|UBD,SH3|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0832--Ubl conjugation
Interpro

IPR001452--SH3_domain
PROSITE

PS50002--SH3
Pfam

PF00018--SH3_1
PRINTS

PR00452--SH3DOMAIN
SMART

SM00326--SH3
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
KEGG sce:YPR154W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001345 Ailuropoda melanoleuca 51.85 2.00e-16 76.60
IUUC-Apl-003322 Anas platyrhynchos 53.70 2.00e-16 77.00
IUUC-Aca-005193 Anolis carolinensis 53.70 2.00e-16 77.00
IUUC-Ago-007965 Ashbya gossypii 55.04 4.00e-33 132.00
IUUC-Ame-010929 Astyanax mexicanus 52.54 6.00e-17 78.60
IUUC-Bta-012932 Bos taurus 51.85 2.00e-16 76.60
IUUC-Cel-018665 Caenorhabditis elegans 43.28 2.00e-13 67.00
IUUC-Cja-019225 Callithrix jacchus 51.85 2.00e-16 76.60
IUUC-Cfa-020887 Canis familiaris 51.85 2.00e-16 76.60
IUUC-Cpo-022488 Cavia porcellus 51.85 2.00e-16 76.60
IUUC-Csa-023326 Chlorocebus sabaeus 51.85 2.00e-16 76.60
IUUC-Cho-024953 Choloepus hoffmanni 51.85 1.00e-16 77.40
IUUC-Dre-028095 Danio rerio 47.83 2.00e-17 80.10
IUUC-Dno-029187 Dasypus novemcinctus 51.85 2.00e-16 77.00
IUUC-Dor-030763 Dipodomys ordii 51.85 2.00e-16 76.60
IUUC-Ete-032354 Echinops telfairi 53.70 2.00e-16 77.00
IUUC-Eca-033222 Equus caballus 51.85 2.00e-16 76.60
IUUC-Eeu-034513 Erinaceus europaeus 51.85 3.00e-16 76.30
IUUC-Fca-036294 Felis catus 51.85 2.00e-16 76.60
IUUC-Fal-037130 Ficedula albicollis 53.70 5.00e-16 75.50
IUUC-Gmo-039546 Gadus morhua 51.85 5.00e-16 75.50
IUUC-Gga-041139 Gallus gallus 53.70 2.00e-16 77.00
IUUC-Gac-041968 Gasterosteus aculeatus 53.70 2.00e-16 77.00
IUUC-Ggo-044562 Gorilla gorilla 51.85 2.00e-16 76.60
IUUC-Hsa-046730 Homo sapiens 51.85 2.00e-16 76.60
IUUC-Hvu-047839 Hordeum vulgare 35.96 1.00e-07 47.40
IUUC-Itr-049025 Ictidomys tridecemlineatus 51.85 2.00e-16 76.60
IUUC-Kpa-049104 Komagataella pastoris 40.00 2.00e-36 143.00
IUUC-Lch-050230 Latimeria chalumnae 55.56 6.00e-17 79.30
IUUC-Loc-052723 Lepisosteus oculatus 53.70 2.00e-16 76.60
IUUC-Laf-053774 Loxodonta africana 53.70 1.00e-16 77.80
IUUC-Mcc-054603 Macaca mulatta 51.85 2.00e-16 76.60
IUUC-Meu-056173 Macropus eugenii 55.56 4.00e-17 79.30
IUUC-Mga-059950 Meleagris gallopavo 53.70 2.00e-16 77.00
IUUC-Mvi-060542 Microbotryum violaceum 48.98 6.00e-11 58.50
IUUC-Mmr-060878 Microcebus murinus 51.85 2.00e-16 76.60
IUUC-Mdo-062454 Monodelphis domestica 55.56 5.00e-17 79.00
IUUC-Mmu-063913 Mus musculus 51.85 2.00e-16 76.60
IUUC-Mpu-066125 Mustela putorius furo 51.85 2.00e-16 76.60
IUUC-Mlu-068007 Myotis lucifugus 51.85 2.00e-16 76.60
IUUC-Nle-069101 Nomascus leucogenys 51.85 2.00e-16 76.60
IUUC-Opr-071075 Ochotona princeps 51.85 2.00e-16 76.60
IUUC-Ont-072253 Oreochromis niloticus 53.70 2.00e-16 76.60
IUUC-Ocu-074583 Oryctolagus cuniculus 51.85 2.00e-16 76.60
IUUC-Ola-086586 Oryzias latipes 51.67 6.00e-16 75.90
IUUC-Oga-089047 Otolemur garnettii 51.85 2.00e-16 76.60
IUUC-Ptr-090678 Pan troglodytes 51.85 2.00e-16 76.60
IUUC-Pan-092090 Papio anubis 51.85 2.00e-16 76.60
IUUC-Psi-093765 Pelodiscus sinensis 53.70 2.00e-16 77.00
IUUC-Pma-094650 Petromyzon marinus 50.94 1.00e-14 70.90
IUUC-Pno-095097 Phaeosphaeria nodorum 51.67 4.00e-12 62.80
IUUC-Ppa-095161 Physcomitrella patens 36.36 1.00e-07 48.50
IUUC-Pfo-096131 Poecilia formosa 53.70 2.00e-16 77.00
IUUC-Pab-098709 Pongo abelii 51.85 2.00e-16 76.60
IUUC-Pca-100581 Procavia capensis 53.70 1.00e-16 77.80
IUUC-Pva-103066 Pteropus vampyrus 51.85 2.00e-16 76.60
IUUC-Rno-105224 Rattus norvegicus 51.85 2.00e-16 76.60
IUUC-Sha-107247 Sarcophilus harrisii 55.56 5.00e-17 78.60
IUUC-Sar-113277 Sorex araneus 51.85 1.00e-16 77.40
IUUC-Ssc-115478 Sus scrofa 51.85 2.00e-16 76.60
IUUC-Tgu-117479 Taeniopygia guttata 53.70 5.00e-16 75.50
IUUC-Tru-118451 Takifugu rubripes 56.60 6.00e-12 62.00
IUUC-Tbe-128097 Tupaia belangeri 51.85 2.00e-16 76.60
IUUC-Vpa-130754 Vicugna pacos 51.85 2.00e-16 76.60
IUUC-Xtr-132275 Xenopus tropicalis 53.70 3.00e-16 76.30
Created Date 25-Jun-2017

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