iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004869.3	ENSCPOT00000025534.1	ENSCPOP00000016380.1
ENSCPOG00000004869.3	ENSCPOT00000004921.2	ENSCPOP00000004382.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-38	127.5	228	258
UBD/Beta-Prp	1.30e-60	205.1	51	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D++ k+WD+
   Q: 228  HDGGIYAISWsPDsTHLLSASGDKSSKIWDV 258
           99*********999****************8 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t+   l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 51   EHAHQVVVAKYAPSGFYVASGDISGKLRIWDTTQREHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 139
           556666678*************************988777632334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    t   h ++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l  +++
   Q: 140  HNKVINSVDIKQTRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHGRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKICALggSKA 227
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           h++ +y +s+++++++l+s+s d++ k+wd+ ++++v t+   +
   Q: 228  HDGGIYAISWSPDSTHLLSASGDKSSKIWDVGANSVVSTFPMGS 271
           *************************************9997544 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

EKVFASLPQV ERGVSKIIGG DPKGNNFLYT NGKCVILRNI DNPAVADIYT EHAHQVVVAK 60
YAPSGFYVAS GDISGKLRIW DTTQREHLLK YEYQPFAGKI KDIAWTEDSK RIAVVGEGRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAAGTGT TCGCCAGCCT CCCCCAAGTG GAAAGGGGCG TATCCAAGAT CATTGGCGGC 60
GACCCCAAGG GCAACAATTT CCTGTACACC AATGGCAAGT GCGTTATACT GAGGAACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.34	1.00e-81	297.00
IUUC-Aml-002368	Ailuropoda melanoleuca	94.84	0.00e+00	1172.00
IUUC-Atr-003160	Amborella trichopoda	37.64	1.00e-115	410.00
IUUC-Apl-004012	Anas platyrhynchos	86.86	0.00e+00	1062.00
IUUC-Aca-004707	Anolis carolinensis	82.53	0.00e+00	1039.00
IUUC-Aly-006465	Arabidopsis lyrata	36.93	1.00e-109	390.00
IUUC-Ath-006740	Arabidopsis thaliana	37.09	3.00e-108	385.00
IUUC-Ago-007920	Ashbya gossypii	28.82	1.00e-74	273.00
IUUC-Acl-008262	Aspergillus clavatus	36.91	4.00e-106	379.00
IUUC-Afl-008471	Aspergillus flavus	30.37	3.00e-67	249.00
IUUC-Afu-008989	Aspergillus fumigatus	38.89	4.00e-96	345.00
IUUC-Ani-009167	Aspergillus nidulans	38.46	6.00e-115	407.00
IUUC-Ang-009595	Aspergillus niger	38.18	1.00e-103	370.00
IUUC-Aor-009908	Aspergillus oryzae	37.22	4.00e-104	372.00
IUUC-Ate-010580	Aspergillus terreus	38.22	1.00e-108	388.00
IUUC-Ame-011269	Astyanax mexicanus	60.35	2.00e-134	472.00
IUUC-Bgr-011996	Blumeria graminis	34.26	5.00e-106	378.00
IUUC-Bta-013278	Bos taurus	94.01	0.00e+00	1189.00
IUUC-Bci-013925	Botrytis cinerea	35.80	3.00e-106	379.00
IUUC-Bdi-014659	Brachypodium distachyon	35.91	2.00e-103	369.00
IUUC-Bol-016043	Brassica oleracea	35.96	8.00e-108	384.00
IUUC-Bra-017139	Brassica rapa	36.27	3.00e-108	385.00
IUUC-Cel-018417	Caenorhabditis elegans	41.13	1.00e-124	440.00
IUUC-Cja-019952	Callithrix jacchus	94.34	0.00e+00	1144.00
IUUC-Cfa-020225	Canis familiaris	94.01	0.00e+00	1167.00
IUUC-Csa-023028	Chlorocebus sabaeus	95.34	0.00e+00	1153.00
IUUC-Cho-025030	Choloepus hoffmanni	67.17	0.00e+00	748.00
IUUC-Cin-025152	Ciona intestinalis	55.56	2.00e-80	291.00
IUUC-Csv-025986	Ciona savignyi	38.28	1.00e-95	343.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.75	2.00e-111	396.00
IUUC-Cne-026814	Cryptococcus neoformans	33.99	5.00e-95	342.00
IUUC-Dre-027498	Danio rerio	79.47	7.00e-93	332.00
IUUC-Dno-029383	Dasypus novemcinctus	93.34	0.00e+00	1127.00
IUUC-Dor-030633	Dipodomys ordii	92.69	0.00e+00	1079.00
IUUC-Dse-031526	Dothistroma septosporum	38.86	4.00e-118	418.00
IUUC-Dme-031597	Drosophila melanogaster	47.93	5.00e-167	580.00
IUUC-Ete-032780	Echinops telfairi	84.18	0.00e+00	1026.00
IUUC-Eca-034306	Equus caballus	92.18	0.00e+00	1129.00
IUUC-Eeu-034531	Erinaceus europaeus	73.52	3.00e-136	478.00
IUUC-Fca-036301	Felis catus	94.84	0.00e+00	1196.00
IUUC-Fal-037361	Ficedula albicollis	87.38	0.00e+00	1121.00
IUUC-Fox-037924	Fusarium oxysporum	36.32	1.00e-101	363.00
IUUC-Fso-038199	Fusarium solani	35.34	2.00e-98	353.00
IUUC-Gmo-039238	Gadus morhua	71.95	0.00e+00	885.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.29	4.00e-94	338.00
IUUC-Gga-040235	Gallus gallus	88.02	0.00e+00	1093.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.00	0.00e+00	920.00
IUUC-Gma-044189	Glycine max	37.40	4.00e-112	398.00
IUUC-Ggo-044632	Gorilla gorilla	93.02	0.00e+00	1119.00
IUUC-Hsa-045792	Homo sapiens	95.01	0.00e+00	1176.00
IUUC-Hvu-047517	Hordeum vulgare	35.41	2.00e-106	379.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	95.17	0.00e+00	1176.00
IUUC-Kpa-049183	Komagataella pastoris	32.56	1.00e-84	306.00
IUUC-Lch-050428	Latimeria chalumnae	76.08	0.00e+00	992.00
IUUC-Lpe-051306	Leersia perrieri	36.29	1.00e-108	387.00
IUUC-Loc-052096	Lepisosteus oculatus	71.69	0.00e+00	892.00
IUUC-Lma-053313	Leptosphaeria maculans	39.15	8.00e-117	416.00
IUUC-Laf-054060	Loxodonta africana	92.01	0.00e+00	1120.00
IUUC-Mcc-055619	Macaca mulatta	93.87	0.00e+00	1135.00
IUUC-Meu-056689	Macropus eugenii	77.35	9.00e-179	620.00
IUUC-Mor-056940	Magnaporthe oryzae	35.46	9.00e-97	347.00
IUUC-Mpo-057557	Magnaporthe poae	30.57	9.00e-68	251.00
IUUC-Mtr-057922	Medicago truncatula	36.35	3.00e-109	389.00
IUUC-Mla-059103	Melampsora laricipopulina	33.22	5.00e-76	278.00
IUUC-Mga-060150	Meleagris gallopavo	88.52	0.00e+00	1093.00
IUUC-Mvi-060448	Microbotryum violaceum	31.28	4.00e-75	275.00
IUUC-Mmr-061226	Microcebus murinus	92.85	0.00e+00	1135.00
IUUC-Mdo-062674	Monodelphis domestica	89.68	0.00e+00	1124.00
IUUC-Mmu-064170	Mus musculus	94.68	0.00e+00	1168.00
IUUC-Mac-065124	Musa acuminata	37.62	2.00e-114	405.00
IUUC-Mpu-066001	Mustela putorius furo	90.54	0.00e+00	1146.00
IUUC-Mlu-067253	Myotis lucifugus	92.68	0.00e+00	1160.00
IUUC-Nfi-068550	Neosartorya fischeri	38.86	2.00e-110	392.00
IUUC-Ncr-068948	Neurospora crassa	37.28	6.00e-113	401.00
IUUC-Nle-070115	Nomascus leucogenys	90.78	0.00e+00	1063.00
IUUC-Opr-070254	Ochotona princeps	90.50	0.00e+00	1092.00
IUUC-Ont-071666	Oreochromis niloticus	75.54	0.00e+00	954.00
IUUC-Oan-073594	Ornithorhynchus anatinus	90.69	5.00e-166	576.00
IUUC-Ocu-074824	Oryctolagus cuniculus	92.01	0.00e+00	1112.00
IUUC-Oba-075010	Oryza barthii	36.68	5.00e-110	391.00
IUUC-Obr-076364	Oryza brachyantha	36.68	1.00e-110	394.00
IUUC-Ogl-077019	Oryza glaberrima	36.68	5.00e-110	391.00
IUUC-Ogu-078496	Oryza glumaepatula	36.68	5.00e-110	391.00
IUUC-Oin-080116	Oryza indica	36.84	1.00e-110	393.00
IUUC-Olo-080290	Oryza longistaminata	36.68	6.00e-110	391.00
IUUC-Ome-081969	Oryza meridionalis	36.68	4.00e-110	391.00
IUUC-Oni-082075	Oryza nivara	36.68	4.00e-110	392.00
IUUC-Opu-083959	Oryza punctata	36.68	1.00e-110	393.00
IUUC-Oru-084711	Oryza rufipogon	36.68	5.00e-110	391.00
IUUC-Osa-085958	Oryza sativa	36.84	1.00e-110	393.00
IUUC-Ola-086968	Oryzias latipes	75.96	0.00e+00	960.00
IUUC-Oga-089108	Otolemur garnettii	93.89	0.00e+00	1193.00
IUUC-Oar-089986	Ovis aries	88.85	0.00e+00	1110.00
IUUC-Ptr-091281	Pan troglodytes	95.33	0.00e+00	1178.00
IUUC-Pan-092585	Papio anubis	95.51	0.00e+00	1156.00
IUUC-Psi-093811	Pelodiscus sinensis	86.86	0.00e+00	1118.00
IUUC-Pma-094542	Petromyzon marinus	69.97	0.00e+00	890.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.98	3.00e-110	392.00
IUUC-Ppa-095876	Physcomitrella patens	36.63	7.00e-112	397.00
IUUC-Pfo-096973	Poecilia formosa	74.62	0.00e+00	979.00
IUUC-Pab-098391	Pongo abelii	94.84	0.00e+00	1152.00
IUUC-Pop-098850	Populus trichocarpa	37.05	2.00e-111	396.00
IUUC-Pca-100257	Procavia capensis	60.26	1.00e-91	330.00
IUUC-Ppe-101578	Prunus persica	37.60	4.00e-114	405.00
IUUC-Pva-102872	Pteropus vampyrus	88.21	0.00e+00	1108.00
IUUC-Pgr-103593	Puccinia graminis	33.06	3.00e-80	292.00
IUUC-Pte-104365	Pyrenophora teres	40.13	1.00e-112	400.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	39.80	6.00e-115	407.00
IUUC-Rno-105737	Rattus norvegicus	95.01	0.00e+00	1200.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.22	3.00e-69	256.00
IUUC-Sha-107084	Sarcophilus harrisii	88.41	0.00e+00	1007.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.50	4.00e-110	391.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.66	2.00e-94	340.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.30	4.00e-106	378.00
IUUC-Smo-109255	Selaginella moellendorffii	34.76	1.00e-100	360.00
IUUC-Sit-109962	Setaria italica	37.66	2.00e-112	399.00
IUUC-Sly-110897	Solanum lycopersicum	38.36	1.00e-115	410.00
IUUC-Stu-111971	Solanum tuberosum	38.20	9.00e-115	407.00
IUUC-Sar-113415	Sorex araneus	71.59	4.00e-110	392.00
IUUC-Sbi-114857	Sorghum bicolor	37.50	2.00e-110	393.00
IUUC-Sre-114900	Sporisorium reilianum	33.83	1.00e-91	330.00
IUUC-Tgu-117256	Taeniopygia guttata	86.86	0.00e+00	1117.00
IUUC-Tru-117871	Takifugu rubripes	69.72	0.00e+00	887.00
IUUC-Tsy-119172	Tarsius syrichta	95.42	1.00e-138	486.00
IUUC-Tni-120339	Tetraodon nigroviridis	70.22	0.00e+00	924.00
IUUC-Tca-121609	Theobroma cacao	36.88	3.00e-111	395.00
IUUC-Tre-122076	Trichoderma reesei	36.02	9.00e-95	340.00
IUUC-Tvi-122528	Trichoderma virens	34.70	1.00e-96	347.00
IUUC-Tae-124549	Triticum aestivum	35.74	3.00e-107	382.00
IUUC-Tur-126845	Triticum urartu	33.82	4.00e-80	291.00
IUUC-Tme-127217	Tuber melanosporum	34.08	1.00e-101	363.00
IUUC-Tbe-127526	Tupaia belangeri	91.20	0.00e+00	1136.00
IUUC-Ttr-128898	Tursiops truncatus	86.05	0.00e+00	1072.00
IUUC-Uma-129631	Ustilago maydis	32.61	8.00e-95	341.00
IUUC-Vda-129732	Verticillium dahliae	35.59	2.00e-92	332.00
IUUC-Vvi-131217	Vitis vinifera	37.93	8.00e-113	400.00
IUUC-Xtr-132860	Xenopus tropicalis	73.69	0.00e+00	939.00
IUUC-Xma-133830	Xiphophorus maculatus	74.96	0.00e+00	983.00
IUUC-Yli-134335	Yarrowia lipolytica	32.13	2.00e-76	280.00
IUUC-Zma-135907	Zea mays	37.50	7.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence