iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090728

Ensembl Protein ID

ENSPTRP00000022180.3

UniProt Accession

H2QJI7; H2QJI7_PANTR

Genbank Protein ID

JAA07204.1; JAA19102.1; JAA31247.1; JAA43228.1

Protein Name

WD repeat and FYVE domain containing 1

Genbank Nucleotide ID

AACZ03019077; GABF01003043; GABD01001853; GABE01001511

Gene Name

WDFY1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012980.5	ENSPTRT00000024051.3	ENSPTRP00000022180.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-18	64.4	240	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH d+v +l++   ++ lvs+s Dg i vW++
   Q: 240  GHHDKVQSLCYlqLTRQLVSCSSDGGIAVWNM 271
           899*******9884489*************97 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAEIHSRPQ SSRPVLLSKI EGHQDAVTAA LLIPKEDGVI TASEDRTIRV WLKRDSGQYW 60
PSIYHTMAAP CSAMAYHHDS RRIFVGQDNG AVMEFHVSED FNKMNFIKTY PAHQNRVSAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGCTGAT GGGCTGCCTG CCGAGGAGGC CGCCGCCGTC GCCGCGCGAA CATGGCGGCC 60
GAAATCCACT CCAGGCCGCA GAGCAGTCGC CCGGTGCTGC TGAGCAAGAT CGAGGGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005634--C:nucleus
GO:0005545--F:1-phosphatidylinositol binding
GO:0046872--F:metal ion binding
GO:0034141--P:positive regulation of toll-like receptor 3 signaling pathway
GO:0034145--P:positive regulation of toll-like receptor 4 signaling pathway

KEGG

ptr:744585

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001526	Ailuropoda melanoleuca	95.78	0.00e+00	815.00
IUUC-Apl-003661	Anas platyrhynchos	91.26	0.00e+00	727.00
IUUC-Aca-005225	Anolis carolinensis	90.44	0.00e+00	782.00
IUUC-Ame-011044	Astyanax mexicanus	76.04	0.00e+00	659.00
IUUC-Bta-012602	Bos taurus	97.32	0.00e+00	848.00
IUUC-Cja-019529	Callithrix jacchus	98.29	0.00e+00	851.00
IUUC-Cfa-020512	Canis familiaris	96.17	0.00e+00	748.00
IUUC-Cpo-022239	Cavia porcellus	95.61	0.00e+00	824.00
IUUC-Csa-023535	Chlorocebus sabaeus	97.97	0.00e+00	712.00
IUUC-Cho-024858	Choloepus hoffmanni	79.02	0.00e+00	653.00
IUUC-Dre-028520	Danio rerio	79.41	0.00e+00	684.00
IUUC-Dno-030005	Dasypus novemcinctus	97.80	0.00e+00	847.00
IUUC-Dor-030500	Dipodomys ordii	96.31	1.00e-176	611.00
IUUC-Ete-032870	Echinops telfairi	80.52	3.00e-147	513.00
IUUC-Eca-033284	Equus caballus	94.40	0.00e+00	810.00
IUUC-Fca-036212	Felis catus	97.25	0.00e+00	755.00
IUUC-Fal-037595	Ficedula albicollis	91.42	0.00e+00	808.00
IUUC-Gmo-038664	Gadus morhua	80.84	0.00e+00	726.00
IUUC-Gga-040400	Gallus gallus	91.67	0.00e+00	809.00
IUUC-Gac-041434	Gasterosteus aculeatus	81.62	0.00e+00	734.00
IUUC-Hsa-045884	Homo sapiens	99.51	0.00e+00	857.00
IUUC-Itr-048815	Ictidomys tridecemlineatus	98.74	0.00e+00	664.00
IUUC-Lch-049995	Latimeria chalumnae	87.32	0.00e+00	774.00
IUUC-Loc-052075	Lepisosteus oculatus	84.94	0.00e+00	750.00
IUUC-Laf-054345	Loxodonta africana	96.34	0.00e+00	843.00
IUUC-Mcc-055293	Macaca mulatta	98.05	0.00e+00	844.00
IUUC-Mga-059585	Meleagris gallopavo	90.41	0.00e+00	724.00
IUUC-Mmr-061268	Microcebus murinus	98.05	0.00e+00	851.00
IUUC-Mdo-061857	Monodelphis domestica	92.16	0.00e+00	812.00
IUUC-Mmu-063789	Mus musculus	97.32	0.00e+00	845.00
IUUC-Mpu-066391	Mustela putorius furo	97.31	0.00e+00	844.00
IUUC-Mlu-067636	Myotis lucifugus	95.62	0.00e+00	748.00
IUUC-Nle-068974	Nomascus leucogenys	98.78	0.00e+00	852.00
IUUC-Opr-070553	Ochotona princeps	83.90	0.00e+00	705.00
IUUC-Oan-073659	Ornithorhynchus anatinus	94.15	0.00e+00	691.00
IUUC-Ocu-074034	Oryctolagus cuniculus	97.56	0.00e+00	848.00
IUUC-Ola-087030	Oryzias latipes	81.37	0.00e+00	733.00
IUUC-Oga-087962	Otolemur garnettii	97.26	0.00e+00	759.00
IUUC-Oar-089377	Ovis aries	97.32	0.00e+00	848.00
IUUC-Pan-092130	Papio anubis	97.80	0.00e+00	844.00
IUUC-Psi-093886	Pelodiscus sinensis	92.01	0.00e+00	728.00
IUUC-Pfo-097254	Poecilia formosa	82.93	0.00e+00	739.00
IUUC-Pab-097594	Pongo abelii	99.27	0.00e+00	855.00
IUUC-Pca-100741	Procavia capensis	87.09	0.00e+00	656.00
IUUC-Pva-102441	Pteropus vampyrus	94.49	0.00e+00	699.00
IUUC-Rno-105767	Rattus norvegicus	96.59	0.00e+00	843.00
IUUC-Sha-106731	Sarcophilus harrisii	92.56	0.00e+00	728.00
IUUC-Ssc-115316	Sus scrofa	97.16	7.00e-125	439.00
IUUC-Tgu-116691	Taeniopygia guttata	91.42	0.00e+00	808.00
IUUC-Tru-118169	Takifugu rubripes	82.11	0.00e+00	734.00
IUUC-Tsy-119047	Tarsius syrichta	84.34	0.00e+00	630.00
IUUC-Tni-120708	Tetraodon nigroviridis	82.89	0.00e+00	733.00
IUUC-Tbe-127442	Tupaia belangeri	97.53	0.00e+00	758.00
IUUC-Ttr-128779	Tursiops truncatus	86.34	0.00e+00	731.00
IUUC-Vpa-130488	Vicugna pacos	94.23	2.00e-119	420.00
IUUC-Xtr-131994	Xenopus tropicalis	80.93	0.00e+00	725.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence