iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067742

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02045386

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000026537.1	ENSMLUT00000029823.1	ENSMLUP00000021075.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-09	38.3	10	60
E3 activity/RING/U-box	3.00e-06	27.3	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENV----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....667777766667777777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNfyiwrplriplKCPNCRSIIeiastGIESLPVNFALRAIIEKYQQE 89
           7899*****************************999999**************9998743321234555688999999999776 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLENVLQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIASTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGACGA GTTAACATGT CCCATTTGTT ATAGTATTTT TGAAGATCCT 60
CGTGTACTAC CATGCTCTCA TACATTTTGT AGAAACTGCT TGGAAAATGT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	88.83	0.00e+00	716.00
IUUC-Apl-003996	Anas platyrhynchos	68.01	1.00e-121	429.00
IUUC-Aca-005141	Anolis carolinensis	54.83	5.00e-127	447.00
IUUC-Ame-011353	Astyanax mexicanus	52.94	5.00e-100	357.00
IUUC-Bta-013440	Bos taurus	90.58	0.00e+00	660.00
IUUC-Cfa-021168	Canis familiaris	90.02	0.00e+00	718.00
IUUC-Cpo-021702	Cavia porcellus	76.13	3.00e-174	604.00
IUUC-Csa-024141	Chlorocebus sabaeus	86.78	0.00e+00	634.00
IUUC-Dre-028408	Danio rerio	47.59	4.00e-90	325.00
IUUC-Dno-029180	Dasypus novemcinctus	88.53	0.00e+00	702.00
IUUC-Eca-034357	Equus caballus	90.27	0.00e+00	708.00
IUUC-Fca-036287	Felis catus	90.75	0.00e+00	723.00
IUUC-Gga-040739	Gallus gallus	56.90	4.00e-131	461.00
IUUC-Ggo-045307	Gorilla gorilla	84.79	0.00e+00	658.00
IUUC-Hsa-045690	Homo sapiens	85.54	0.00e+00	662.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	89.78	0.00e+00	721.00
IUUC-Laf-054522	Loxodonta africana	85.82	0.00e+00	698.00
IUUC-Mcc-055145	Macaca mulatta	87.03	0.00e+00	672.00
IUUC-Meu-056214	Macropus eugenii	46.83	1.00e-56	213.00
IUUC-Mmr-061197	Microcebus murinus	91.77	0.00e+00	732.00
IUUC-Mdo-062631	Monodelphis domestica	60.50	2.00e-128	451.00
IUUC-Mmu-064217	Mus musculus	83.87	0.00e+00	664.00
IUUC-Mpu-065691	Mustela putorius furo	91.52	0.00e+00	731.00
IUUC-Nle-069722	Nomascus leucogenys	87.28	0.00e+00	702.00
IUUC-Oan-073382	Ornithorhynchus anatinus	59.06	7.00e-129	453.00
IUUC-Oar-089206	Ovis aries	89.50	0.00e+00	730.00
IUUC-Pan-092189	Papio anubis	87.28	0.00e+00	674.00
IUUC-Psi-093523	Pelodiscus sinensis	61.23	5.00e-139	487.00
IUUC-Pma-094162	Petromyzon marinus	33.23	3.00e-47	181.00
IUUC-Pfo-096032	Poecilia formosa	46.58	6.00e-88	317.00
IUUC-Pva-103089	Pteropus vampyrus	89.30	0.00e+00	697.00
IUUC-Pgr-103338	Puccinia graminis	38.71	1.00e-06	46.60
IUUC-Rno-105440	Rattus norvegicus	85.54	0.00e+00	674.00
IUUC-Ssc-115809	Sus scrofa	88.28	0.00e+00	676.00
IUUC-Tru-118402	Takifugu rubripes	44.35	3.00e-93	335.00
IUUC-Tni-119737	Tetraodon nigroviridis	45.66	8.00e-87	313.00
IUUC-Ttr-128921	Tursiops truncatus	88.53	0.00e+00	685.00
IUUC-Vpa-130397	Vicugna pacos	90.32	0.00e+00	723.00
IUUC-Xtr-132752	Xenopus tropicalis	48.70	8.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence