iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072197

Ensembl Protein ID

ENSONIP00000015592.1

UniProt Accession

I3K397; I3K397_ORENI

Genbank Protein ID

ENSONIP00000015592

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AERX01018760

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000012377.1	ENSONIT00000015605.1	ENSONIP00000015592.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.20e-16	58.2	858	898

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 858  WCFVCSKGGQ----LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCR 898
           8*********....*******************....9***8.******8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

VMDSKGSSLP SMPEPANPIS MKQPPESLSV RKGRGDMSSD PAMLMDKAAA QLAATLQDSV 60
LQKMAGHNNH SHDRLKDLTS RMLNGDQDSL PELCTPEPPM FKGAEAPATN GTHQHNCTPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAAGTTAG TATTTTTCGC GCTGGTTGGC CTGAGAGTTT GAGTTTCCCG CAAGCTTTTG 60
ATTCGACTTG AATGAAATCC TTCGCTTTAC ATGATGAATA CGGGTATTTT TTCCCTTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	72.21	0.00e+00	1058.00
IUUC-Apl-003677	Anas platyrhynchos	72.65	0.00e+00	1086.00
IUUC-Aca-004278	Anolis carolinensis	64.13	0.00e+00	1084.00
IUUC-Ame-011932	Astyanax mexicanus	76.44	0.00e+00	1169.00
IUUC-Bta-012522	Bos taurus	72.70	0.00e+00	1048.00
IUUC-Cja-018908	Callithrix jacchus	71.93	0.00e+00	1054.00
IUUC-Cfa-020894	Canis familiaris	72.07	0.00e+00	1068.00
IUUC-Cpo-021982	Cavia porcellus	72.47	0.00e+00	1066.00
IUUC-Csa-023807	Chlorocebus sabaeus	71.74	0.00e+00	1055.00
IUUC-Csv-026298	Ciona savignyi	41.41	5.00e-60	225.00
IUUC-Dre-027492	Danio rerio	80.11	0.00e+00	1208.00
IUUC-Dor-031103	Dipodomys ordii	65.89	0.00e+00	918.00
IUUC-Dme-032193	Drosophila melanogaster	36.72	2.00e-118	421.00
IUUC-Ete-032488	Echinops telfairi	66.42	0.00e+00	919.00
IUUC-Eca-034066	Equus caballus	72.36	0.00e+00	1057.00
IUUC-Eeu-035199	Erinaceus europaeus	55.71	4.00e-115	409.00
IUUC-Fca-035434	Felis catus	67.99	0.00e+00	993.00
IUUC-Fal-037113	Ficedula albicollis	49.61	0.00e+00	1248.00
IUUC-Gmo-039686	Gadus morhua	79.02	0.00e+00	1174.00
IUUC-Gga-040273	Gallus gallus	72.33	0.00e+00	1088.00
IUUC-Gac-042123	Gasterosteus aculeatus	67.40	0.00e+00	1803.00
IUUC-Ggo-044643	Gorilla gorilla	71.78	0.00e+00	1058.00
IUUC-Hsa-046380	Homo sapiens	71.89	0.00e+00	1055.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	70.85	0.00e+00	1028.00
IUUC-Lch-050217	Latimeria chalumnae	70.63	0.00e+00	1093.00
IUUC-Loc-052766	Lepisosteus oculatus	69.41	0.00e+00	1171.00
IUUC-Laf-053780	Loxodonta africana	72.07	0.00e+00	1058.00
IUUC-Mcc-054928	Macaca mulatta	71.64	0.00e+00	1058.00
IUUC-Mla-058968	Melampsora laricipopulina	30.65	8.90e-01	28.10
IUUC-Mga-059576	Meleagris gallopavo	72.36	0.00e+00	1082.00
IUUC-Mmr-061045	Microcebus murinus	71.92	0.00e+00	1065.00
IUUC-Mdo-062576	Monodelphis domestica	72.36	0.00e+00	1075.00
IUUC-Mmu-063640	Mus musculus	72.04	0.00e+00	1060.00
IUUC-Mpu-066512	Mustela putorius furo	72.50	0.00e+00	1064.00
IUUC-Nle-069896	Nomascus leucogenys	72.30	0.00e+00	982.00
IUUC-Ocu-074758	Oryctolagus cuniculus	70.76	0.00e+00	1042.00
IUUC-Olo-080702	Oryza longistaminata	41.01	2.00e-44	174.00
IUUC-Opu-083371	Oryza punctata	43.72	1.00e-44	175.00
IUUC-Oar-089736	Ovis aries	73.31	0.00e+00	947.00
IUUC-Ptr-091055	Pan troglodytes	71.89	0.00e+00	1055.00
IUUC-Pan-092752	Papio anubis	72.04	0.00e+00	1040.00
IUUC-Psi-093620	Pelodiscus sinensis	73.32	0.00e+00	1097.00
IUUC-Pfo-097464	Poecilia formosa	71.52	0.00e+00	1802.00
IUUC-Pab-098051	Pongo abelii	71.78	0.00e+00	1058.00
IUUC-Pca-100273	Procavia capensis	72.50	0.00e+00	1039.00
IUUC-Pva-102473	Pteropus vampyrus	69.75	0.00e+00	929.00
IUUC-Rno-105056	Rattus norvegicus	71.78	0.00e+00	1056.00
IUUC-Sha-107494	Sarcophilus harrisii	72.51	0.00e+00	1072.00
IUUC-Sar-113310	Sorex araneus	54.09	0.00e+00	1051.00
IUUC-Sbi-114581	Sorghum bicolor	33.04	7.00e-10	58.20
IUUC-Ssc-116344	Sus scrofa	70.62	0.00e+00	1044.00
IUUC-Tgu-116786	Taeniopygia guttata	49.12	0.00e+00	1234.00
IUUC-Tru-117638	Takifugu rubripes	67.13	0.00e+00	1714.00
IUUC-Tsy-118937	Tarsius syrichta	72.33	0.00e+00	1052.00
IUUC-Tni-120452	Tetraodon nigroviridis	71.55	0.00e+00	1556.00
IUUC-Tae-125237	Triticum aestivum	27.27	3.00e-06	45.80
IUUC-Tbe-127291	Tupaia belangeri	68.76	0.00e+00	997.00
IUUC-Xtr-132673	Xenopus tropicalis	51.68	0.00e+00	1132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence