iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005189

UUCD1 version

UUC-AnC-00463

Ensembl Protein ID

ENSACAP00000000961.3

UniProt Accession

G1K908; G1K908_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBR2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000759.3	ENSACAT00000000989.3	ENSACAP00000000961.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-09	38.4	1109	1214
E3 activity/N-recognin/N-domain	1.40e-39	134.0	227	302
E3 activity/N-recognin/UBR-box	8.00e-30	103.1	97	168

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...............kd.............................gplvlpCgHvfhadClqkw.............. 29
           C++C+e+                ++                             g+++++CgH++ha+C+q++              
   Q: 1109 CILCQEEQevkmdnramvlaafvQRstvlsknrskvipdpekhdplfmhpdlscGVHTGSCGHIMHAHCWQRYfdavqakeqrrqqr 1195
           8888665544443333333333300333333333333333333333333333338******************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1196 lrvHTSYDVENGEFLCPLC 1214
           ******************* PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd+++c++ak++i++n++++++ pLkV+v
   Q: 227  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCDQAKSVIVRNTSRQTK-PLKVQV 302
           9*********************************************************************.****98 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkllk 72
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  +vH++H+y++++sggggfCdCGdteAw++g+ C+k+++
   Q: 97   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSVHREHRYRMTTSGGGGFCDCGDTEAWKEGPCCQKHEH 168
           68******************************************************************9975 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASSLEAEVQ AFDGSLLECS AEETALKWLQ TSDLPKEIYK HLAYYVPKIY CKGPNPAPQR 60
EDMLAQHVLL GPMEWYLCGE DPAFGFQKLE QSNKPSHLCG RVFKVGEPTY SCRDCAVDPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGAACAGG GCTGCTTAAG TAAATAGAGG CGTGGCTGGG TGGGGCGTGG CCTCTGGGCG 60
GAAGTGGGCT CTTCCTGGCG AGCCTGCTTC CGGTTGTCAC TTACTCGTCG GCGGGGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000785--C:chromatin
GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	27.17	6.00e-23	103.00
IUUC-Aml-001876	Ailuropoda melanoleuca	75.81	0.00e+00	2453.00
IUUC-Atr-002501	Amborella trichopoda	30.42	2.00e-29	125.00
IUUC-Apl-003828	Anas platyrhynchos	87.09	0.00e+00	3065.00
IUUC-Aly-005901	Arabidopsis lyrata	32.39	4.00e-26	114.00
IUUC-Ath-007148	Arabidopsis thaliana	31.46	6.00e-25	110.00
IUUC-Ago-007752	Ashbya gossypii	23.62	2.00e-24	109.00
IUUC-Afl-008479	Aspergillus flavus	24.02	2.00e-48	189.00
IUUC-Afu-008929	Aspergillus fumigatus	24.49	2.00e-53	205.00
IUUC-Ani-009334	Aspergillus nidulans	24.43	4.00e-52	201.00
IUUC-Ang-009550	Aspergillus niger	24.32	2.00e-50	195.00
IUUC-Aor-010124	Aspergillus oryzae	23.99	7.00e-49	190.00
IUUC-Ate-010550	Aspergillus terreus	23.60	2.00e-47	185.00
IUUC-Ame-011917	Astyanax mexicanus	74.06	0.00e+00	2509.00
IUUC-Bta-012768	Bos taurus	83.72	0.00e+00	2957.00
IUUC-Bdi-014635	Brachypodium distachyon	24.86	7.00e-31	130.00
IUUC-Bol-015669	Brassica oleracea	30.74	2.00e-30	128.00
IUUC-Bra-017776	Brassica rapa	30.74	6.00e-31	130.00
IUUC-Cel-018476	Caenorhabditis elegans	31.69	6.00e-82	300.00
IUUC-Cja-019797	Callithrix jacchus	84.44	0.00e+00	2329.00
IUUC-Cfa-020950	Canis familiaris	86.16	0.00e+00	3028.00
IUUC-Cpo-022385	Cavia porcellus	83.49	0.00e+00	2949.00
IUUC-Csa-024082	Chlorocebus sabaeus	85.71	0.00e+00	3014.00
IUUC-Cho-025029	Choloepus hoffmanni	78.75	0.00e+00	1979.00
IUUC-Cin-025148	Ciona intestinalis	35.27	4.00e-137	481.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	24.45	2.00e-56	215.00
IUUC-Cne-026823	Cryptococcus neoformans	22.31	2.00e-35	145.00
IUUC-Dre-028343	Danio rerio	72.74	0.00e+00	2491.00
IUUC-Dno-030002	Dasypus novemcinctus	82.94	0.00e+00	1762.00
IUUC-Dor-030207	Dipodomys ordii	72.73	0.00e+00	1457.00
IUUC-Dse-031531	Dothistroma septosporum	24.81	2.00e-58	222.00
IUUC-Dme-031910	Drosophila melanogaster	33.66	0.00e+00	852.00
IUUC-Ete-033162	Echinops telfairi	78.81	0.00e+00	1301.00
IUUC-Eca-033454	Equus caballus	84.92	0.00e+00	2986.00
IUUC-Eeu-034783	Erinaceus europaeus	69.00	0.00e+00	1350.00
IUUC-Fca-036588	Felis catus	85.55	0.00e+00	2999.00
IUUC-Fal-036919	Ficedula albicollis	86.78	0.00e+00	3001.00
IUUC-Fox-037984	Fusarium oxysporum	25.12	1.00e-40	162.00
IUUC-Fso-038463	Fusarium solani	24.44	6.00e-45	177.00
IUUC-Gmo-039698	Gadus morhua	69.46	0.00e+00	1639.00
IUUC-Ggr-040070	Gaeumannomyces graminis	25.40	1.00e-46	182.00
IUUC-Gga-041123	Gallus gallus	87.63	0.00e+00	3111.00
IUUC-Gac-042622	Gasterosteus aculeatus	66.97	0.00e+00	2208.00
IUUC-Gma-043622	Glycine max	29.94	5.00e-28	120.00
IUUC-Ggo-045583	Gorilla gorilla	84.14	0.00e+00	2978.00
IUUC-Hsa-046343	Homo sapiens	84.91	0.00e+00	2989.00
IUUC-Hvu-047626	Hordeum vulgare	28.62	1.00e-28	122.00
IUUC-Kpa-049088	Komagataella pastoris	22.94	5.00e-44	174.00
IUUC-Lch-049649	Latimeria chalumnae	74.82	0.00e+00	2595.00
IUUC-Lpe-051516	Leersia perrieri	25.78	2.00e-31	132.00
IUUC-Loc-052818	Lepisosteus oculatus	75.52	0.00e+00	2653.00
IUUC-Lma-053059	Leptosphaeria maculans	23.47	3.00e-49	191.00
IUUC-Laf-054142	Loxodonta africana	84.36	0.00e+00	2974.00
IUUC-Mcc-055677	Macaca mulatta	85.48	0.00e+00	2999.00
IUUC-Meu-056204	Macropus eugenii	64.45	0.00e+00	704.00
IUUC-Mor-057051	Magnaporthe oryzae	23.61	8.00e-52	200.00
IUUC-Mpo-057372	Magnaporthe poae	26.24	7.00e-49	189.00
IUUC-Mtr-058538	Medicago truncatula	30.24	1.00e-29	126.00
IUUC-Mla-058963	Melampsora laricipopulina	23.71	4.00e-63	237.00
IUUC-Mga-059698	Meleagris gallopavo	88.03	0.00e+00	3086.00
IUUC-Mvi-060535	Microbotryum violaceum	24.54	2.00e-47	185.00
IUUC-Mmr-060901	Microcebus murinus	82.97	0.00e+00	2910.00
IUUC-Mdo-062014	Monodelphis domestica	88.43	0.00e+00	3114.00
IUUC-Mmu-063699	Mus musculus	81.95	0.00e+00	2881.00
IUUC-Mpu-066153	Mustela putorius furo	85.99	0.00e+00	3028.00
IUUC-Mlu-068151	Myotis lucifugus	83.72	0.00e+00	2931.00
IUUC-Nfi-068403	Neosartorya fischeri	24.39	4.00e-54	207.00
IUUC-Ncr-068864	Neurospora crassa	22.78	2.00e-53	205.00
IUUC-Nle-069529	Nomascus leucogenys	85.65	0.00e+00	3016.00
IUUC-Opr-071107	Ochotona princeps	78.87	0.00e+00	1199.00
IUUC-Ont-072189	Oreochromis niloticus	66.95	0.00e+00	2188.00
IUUC-Oan-072893	Ornithorhynchus anatinus	86.67	0.00e+00	3031.00
IUUC-Ocu-074082	Oryctolagus cuniculus	83.61	0.00e+00	2946.00
IUUC-Obr-076117	Oryza brachyantha	25.59	2.00e-27	119.00
IUUC-Ome-081738	Oryza meridionalis	22.81	7.00e-15	77.40
IUUC-Opu-083202	Oryza punctata	27.09	8.00e-28	120.00
IUUC-Ola-087460	Oryzias latipes	65.20	0.00e+00	2163.00
IUUC-Olu-087832	Ostreococcus lucimarinus	26.67	2.20e-01	31.20
IUUC-Oga-088432	Otolemur garnettii	84.18	0.00e+00	2979.00
IUUC-Oar-090206	Ovis aries	84.02	0.00e+00	2975.00
IUUC-Ptr-091180	Pan troglodytes	84.45	0.00e+00	2980.00
IUUC-Pan-092375	Papio anubis	85.54	0.00e+00	3010.00
IUUC-Psi-093049	Pelodiscus sinensis	88.56	0.00e+00	3094.00
IUUC-Pno-094877	Phaeosphaeria nodorum	23.08	1.00e-45	179.00
IUUC-Pfo-096524	Poecilia formosa	64.51	0.00e+00	2065.00
IUUC-Pab-097989	Pongo abelii	83.88	0.00e+00	2929.00
IUUC-Pca-100207	Procavia capensis	70.76	0.00e+00	1137.00
IUUC-Ppe-101802	Prunus persica	30.15	9.00e-28	120.00
IUUC-Pgr-103372	Puccinia graminis	23.63	6.00e-49	190.00
IUUC-Ptt-103878	Puccinia triticina	23.46	2.00e-46	182.00
IUUC-Pte-104174	Pyrenophora teres	23.49	2.00e-49	191.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	23.59	4.00e-50	194.00
IUUC-Rno-105567	Rattus norvegicus	82.01	0.00e+00	2836.00
IUUC-Sha-106980	Sarcophilus harrisii	88.42	0.00e+00	2987.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	24.04	6.00e-50	193.00
IUUC-Smo-108719	Selaginella moellendorffii	33.68	5.00e-31	130.00
IUUC-Sit-110716	Setaria italica	28.09	8.00e-31	130.00
IUUC-Sly-111286	Solanum lycopersicum	29.52	1.00e-28	122.00
IUUC-Sar-113332	Sorex araneus	78.47	0.00e+00	1977.00
IUUC-Sbi-114577	Sorghum bicolor	28.85	5.00e-31	130.00
IUUC-Ssc-115525	Sus scrofa	85.88	0.00e+00	2333.00
IUUC-Tgu-116943	Taeniopygia guttata	87.76	0.00e+00	3109.00
IUUC-Tru-117673	Takifugu rubripes	65.39	0.00e+00	2188.00
IUUC-Tsy-119032	Tarsius syrichta	84.83	0.00e+00	1704.00
IUUC-Tni-119987	Tetraodon nigroviridis	65.38	0.00e+00	2141.00
IUUC-Tca-121077	Theobroma cacao	26.61	4.00e-28	121.00
IUUC-Tre-122137	Trichoderma reesei	24.25	9.00e-62	233.00
IUUC-Tvi-122272	Trichoderma virens	23.28	2.00e-55	212.00
IUUC-Tae-125501	Triticum aestivum	28.21	9.00e-30	125.00
IUUC-Tur-126562	Triticum urartu	30.03	1.00e-28	122.00
IUUC-Tme-127156	Tuber melanosporum	23.77	7.00e-53	203.00
IUUC-Tbe-128103	Tupaia belangeri	78.02	0.00e+00	1113.00
IUUC-Ttr-128253	Tursiops truncatus	86.68	0.00e+00	2004.00
IUUC-Uma-129344	Ustilago maydis	26.54	4.00e-50	194.00
IUUC-Vda-129778	Verticillium dahliae	24.90	1.00e-49	192.00
IUUC-Vpa-130540	Vicugna pacos	81.26	0.00e+00	2671.00
IUUC-Vvi-131290	Vitis vinifera	30.88	3.00e-29	124.00
IUUC-Xtr-132690	Xenopus tropicalis	79.91	0.00e+00	2847.00
IUUC-Xma-133748	Xiphophorus maculatus	65.11	0.00e+00	2023.00
IUUC-Yli-134662	Yarrowia lipolytica	25.51	2.00e-31	131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence