iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054043

UUCD1 version

UUC-LoA-01102

Ensembl Protein ID

ENSLAFP00000020929.1

UniProt Accession

G3TZC1; G3TZC1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007361.3	ENSLAFT00000007364.3	ENSLAFP00000006191.3
ENSLAFG00000007361.3	ENSLAFT00000029096.1	ENSLAFP00000020929.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.80e-73	246.6	89	419
ULD/UDP/UBQ/UBQ_Other	1.20e-10	41.4	963	1025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l               ++ee+ + + ++++++lq lf+ l++s++++++p+ ++kal+   
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcsdyMMGDGIQEEK-DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG--- 173
           6*****************************9555555443333443332.67888******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f+
   Q: 174  --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFY 237
           ..78899*******************.......................457889999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + L
   Q: 238  ELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEIL 321
           **********.....9************************************************************************* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg................... 327
           d++p+++++       + YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +                   
   Q: 322  DMEPYVEHKGG----GYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkg 406
           ******99554....79**************************44555************9999998665999**************** PP
   S: 328  ....staYvlfYk 336
               ++aY+l+Y+
   Q: 407  thcsRNAYMLVYR 419
           ************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 963  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 1025
           344489999************************************************988775 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCGC GTCTGCAGTT GGAAAAGGCG GCCTGGCGCT GGGCGGAGAC GGTGCGGCCC 60
GAGGAGGTGT CGCAGGAGCA TATCGAGACC GCCTACCGCA TCTGGCTGGA GCCCTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	28.80	5.00e-81	296.00
IUUC-Aml-001357	Ailuropoda melanoleuca	96.78	0.00e+00	2048.00
IUUC-Atr-002976	Amborella trichopoda	26.43	8.00e-81	295.00
IUUC-Apl-003773	Anas platyrhynchos	86.33	0.00e+00	1680.00
IUUC-Aca-004466	Anolis carolinensis	81.07	0.00e+00	868.00
IUUC-Aly-006249	Arabidopsis lyrata	30.03	2.00e-71	264.00
IUUC-Ath-006700	Arabidopsis thaliana	30.97	2.00e-80	294.00
IUUC-Ame-011554	Astyanax mexicanus	67.28	0.00e+00	1435.00
IUUC-Bta-012573	Bos taurus	95.74	0.00e+00	2053.00
IUUC-Bdi-014149	Brachypodium distachyon	32.32	7.00e-82	298.00
IUUC-Bol-016289	Brassica oleracea	26.57	1.00e-80	295.00
IUUC-Bra-017205	Brassica rapa	26.00	5.00e-72	266.00
IUUC-Cel-018662	Caenorhabditis elegans	27.65	2.00e-28	122.00
IUUC-Cja-019991	Callithrix jacchus	95.32	0.00e+00	2055.00
IUUC-Cfa-020294	Canis familiaris	96.96	0.00e+00	2093.00
IUUC-Cpo-021706	Cavia porcellus	93.56	0.00e+00	1931.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	31.11	5.00e-43	171.00
IUUC-Csa-023931	Chlorocebus sabaeus	96.68	0.00e+00	2073.00
IUUC-Cho-024566	Choloepus hoffmanni	91.53	5.00e-158	551.00
IUUC-Cin-025307	Ciona intestinalis	47.16	8.00e-76	276.00
IUUC-Csv-026006	Ciona savignyi	36.82	3.00e-151	529.00
IUUC-Cne-027065	Cryptococcus neoformans	28.70	3.00e-67	250.00
IUUC-Dre-027624	Danio rerio	67.85	0.00e+00	1481.00
IUUC-Dno-029633	Dasypus novemcinctus	98.95	0.00e+00	1329.00
IUUC-Dor-030809	Dipodomys ordii	75.63	0.00e+00	1207.00
IUUC-Ete-032818	Echinops telfairi	91.87	0.00e+00	958.00
IUUC-Eca-033692	Equus caballus	96.87	0.00e+00	2076.00
IUUC-Eeu-035185	Erinaceus europaeus	72.98	0.00e+00	788.00
IUUC-Fca-035676	Felis catus	96.49	0.00e+00	2086.00
IUUC-Fal-036913	Ficedula albicollis	85.88	0.00e+00	1827.00
IUUC-Gmo-038532	Gadus morhua	65.34	0.00e+00	1399.00
IUUC-Gga-041041	Gallus gallus	85.78	0.00e+00	1821.00
IUUC-Gac-042570	Gasterosteus aculeatus	66.60	0.00e+00	1439.00
IUUC-Gma-044136	Glycine max	27.48	3.00e-95	343.00
IUUC-Ggo-045367	Gorilla gorilla	91.67	0.00e+00	1932.00
IUUC-Hsa-046019	Homo sapiens	96.77	0.00e+00	2076.00
IUUC-Hvu-047303	Hordeum vulgare	33.58	1.00e-65	244.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	95.73	0.00e+00	2061.00
IUUC-Lch-049989	Latimeria chalumnae	74.84	0.00e+00	1627.00
IUUC-Lpe-051612	Leersia perrieri	32.44	3.00e-79	290.00
IUUC-Loc-052756	Lepisosteus oculatus	70.81	0.00e+00	1545.00
IUUC-Mcc-054986	Macaca mulatta	95.14	0.00e+00	2053.00
IUUC-Meu-056228	Macropus eugenii	75.62	0.00e+00	856.00
IUUC-Mtr-058762	Medicago truncatula	29.63	6.00e-88	318.00
IUUC-Mga-059896	Meleagris gallopavo	85.18	0.00e+00	1721.00
IUUC-Mvi-060269	Microbotryum violaceum	37.04	4.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	96.96	0.00e+00	2076.00
IUUC-Mdo-062506	Monodelphis domestica	92.22	0.00e+00	1987.00
IUUC-Mmu-063642	Mus musculus	93.16	0.00e+00	2023.00
IUUC-Mac-064896	Musa acuminata	31.48	7.00e-78	285.00
IUUC-Mpu-066194	Mustela putorius furo	96.77	0.00e+00	2078.00
IUUC-Mlu-067233	Myotis lucifugus	95.48	0.00e+00	2053.00
IUUC-Nle-069052	Nomascus leucogenys	95.68	0.00e+00	2060.00
IUUC-Opr-070890	Ochotona princeps	95.24	0.00e+00	1252.00
IUUC-Ont-071450	Oreochromis niloticus	63.80	0.00e+00	1373.00
IUUC-Oan-073252	Ornithorhynchus anatinus	88.06	0.00e+00	1051.00
IUUC-Ocu-073796	Oryctolagus cuniculus	95.57	0.00e+00	1771.00
IUUC-Oba-075563	Oryza barthii	31.88	2.00e-80	294.00
IUUC-Obr-076394	Oryza brachyantha	32.13	6.00e-81	295.00
IUUC-Ogl-077339	Oryza glaberrima	38.23	5.00e-41	160.00
IUUC-Ogu-079007	Oryza glumaepatula	32.70	6.00e-74	272.00
IUUC-Oin-079997	Oryza indica	31.88	8.00e-81	295.00
IUUC-Olo-080364	Oryza longistaminata	31.88	1.00e-80	294.00
IUUC-Ome-081165	Oryza meridionalis	32.70	2.00e-74	274.00
IUUC-Oni-083026	Oryza nivara	31.88	8.00e-81	295.00
IUUC-Opu-083284	Oryza punctata	33.86	3.00e-74	273.00
IUUC-Oru-084797	Oryza rufipogon	31.88	1.00e-80	295.00
IUUC-Osa-086221	Oryza sativa	38.23	5.00e-41	160.00
IUUC-Ola-086568	Oryzias latipes	66.67	0.00e+00	1446.00
IUUC-Oga-088687	Otolemur garnettii	94.75	0.00e+00	2043.00
IUUC-Oar-090345	Ovis aries	95.85	0.00e+00	1960.00
IUUC-Ptr-090734	Pan troglodytes	96.68	0.00e+00	2075.00
IUUC-Pan-091704	Papio anubis	93.10	0.00e+00	1973.00
IUUC-Psi-092937	Pelodiscus sinensis	85.76	0.00e+00	1595.00
IUUC-Ppa-095808	Physcomitrella patens	27.37	4.00e-70	260.00
IUUC-Pab-098129	Pongo abelii	96.77	0.00e+00	2076.00
IUUC-Pop-099738	Populus trichocarpa	26.71	2.00e-80	293.00
IUUC-Pca-100647	Procavia capensis	98.79	0.00e+00	692.00
IUUC-Ppe-102091	Prunus persica	31.21	6.00e-84	305.00
IUUC-Pva-102719	Pteropus vampyrus	96.20	0.00e+00	2053.00
IUUC-Rno-105363	Rattus norvegicus	92.60	0.00e+00	2010.00
IUUC-Sha-107620	Sarcophilus harrisii	88.78	0.00e+00	1848.00
IUUC-Smo-109487	Selaginella moellendorffii	28.24	5.00e-86	312.00
IUUC-Sit-110683	Setaria italica	32.50	1.00e-80	295.00
IUUC-Sly-111377	Solanum lycopersicum	29.58	4.00e-81	296.00
IUUC-Stu-111969	Solanum tuberosum	31.61	5.00e-70	258.00
IUUC-Sar-113099	Sorex araneus	94.43	0.00e+00	1724.00
IUUC-Sbi-113833	Sorghum bicolor	41.81	2.00e-56	212.00
IUUC-Ssc-115279	Sus scrofa	89.26	0.00e+00	1362.00
IUUC-Tgu-117519	Taeniopygia guttata	83.40	0.00e+00	1673.00
IUUC-Tru-117651	Takifugu rubripes	65.68	0.00e+00	1420.00
IUUC-Tsy-119201	Tarsius syrichta	92.77	0.00e+00	1807.00
IUUC-Tni-120840	Tetraodon nigroviridis	66.79	0.00e+00	1453.00
IUUC-Tca-121674	Theobroma cacao	29.05	2.00e-84	307.00
IUUC-Tae-125814	Triticum aestivum	27.02	2.00e-84	307.00
IUUC-Tur-126599	Triticum urartu	29.14	3.00e-80	293.00
IUUC-Tbe-127782	Tupaia belangeri	85.48	0.00e+00	1755.00
IUUC-Ttr-128312	Tursiops truncatus	95.45	0.00e+00	2035.00
IUUC-Vpa-130348	Vicugna pacos	96.53	0.00e+00	1970.00
IUUC-Vvi-131353	Vitis vinifera	26.82	3.00e-84	306.00
IUUC-Xtr-132172	Xenopus tropicalis	69.61	0.00e+00	1344.00
IUUC-Xma-133263	Xiphophorus maculatus	66.85	0.00e+00	1402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence