iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111487

Ensembl Protein ID

Solyc05g053690.1.1

UniProt Accession

K4C249; K4C249_SOLLC

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc05g053690.1	Solyc05g053690.1.1	Solyc05g053690.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-78	264.9	231	742

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC++NS++Q L++++ lr+++l+     ++        g+l+  l+klf+        k++v+p++l+ +++++a++f+gy+qq
   Q: 231  GLVNLGNTCFFNSIMQNLLAMNRLRDYFLK-----FDG-----FAGPLTADLKKLFTDTSneAALKGSVNPKSLFGSICTKAPQFRGYQQQ 311
           9*****************************.....544.....4689**********9988889999************************ PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkee 181
           D++E+l++lld l +e           ++  + + +s++ + k  ++ +++++++F+g+l+s++ clec+++s+ +epfldlslpv+ k+ 
   Q: 312  DSHELLRCLLDCLCTEA----------LTRRKLI-KSSQDDGKSRSSCPTFVDEIFGGRLSSTVSCLECGHTSVVYEPFLDLSLPVQTKKP 391
           *************9988..........1112212.22234578899999**************************************9997 PP
   S: 182  tkke....................................................................................... 185
            +k                                                                                        
   Q: 392  PSKGaqsvshakiskppkrsgkvfskvsrdaaslnsqrkgekslsrvyprvpvtegmilpsdtslestdagvmadntgltsqdscftqksr 482
           666599************************************************************************************* PP
   S: 186  ........................................................................................... 185
                                                                                                      
   Q: 483  neetcegvtrqlamvddstwldfleqetlpnvddaasevdhivtnqgsetgsvqsvdplqnnldadtemkltctnstrspndlmclddqgq 573
           ******************************************************************************************* PP
   S: 186  ........................................................................................... 185
                                                                                                      
   Q: 574  skspdcdiasefskkllikesekissvdsnhgtdsftrlsedeaplrlqeseilllpykevtstagdmlnegcevssaavgreevsfnepe 664
           ******************************************************************************************* PP
   S: 186  ..........................................slqdcLesftkeeelegenk.yycekckkkqeaekkl 221
                                                     s+++cL+ ftk+e l +++  ++ce+c+k    ek++
   Q: 665  sdaqslcnasvsqanglreasftvsnismsdpeelditdapvSVKSCLAYFTKPELLSKSEHaWQCENCTKVL-KEKRM 742
           *********************************************************986655******9755.45554 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MGKRAKKKAR SGVKETRNPV ASANRIDEKS SPNIDTPDVA VFVVKDRKEC PHVDKVIDVG 60
KVSAKLESSE PVRCEDCREG AADRQASRTK GKHGKKKGSA DPKKKSKAIW VCLVCGHFSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAAA GGGCTAAAAA AAAGGCTAGA AGTGGTGTCA AGGAGACGCG GAATCCCGTT 60
GCATCTGCAA ATCGTATTGA TGAAAAGAGC AGTCCGAATA TTGATACTCC TGATGTTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sly:101245656

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	30.61	3.00e-58	219.00
IUUC-Aml-001931	Ailuropoda melanoleuca	30.61	7.00e-36	145.00
IUUC-Atr-003015	Amborella trichopoda	33.13	2.00e-84	306.00
IUUC-Apl-004145	Anas platyrhynchos	31.20	9.00e-40	157.00
IUUC-Aca-004314	Anolis carolinensis	29.74	6.00e-34	138.00
IUUC-Ath-007211	Arabidopsis thaliana	39.40	1.00e-154	540.00
IUUC-Bta-013362	Bos taurus	29.95	7.00e-35	141.00
IUUC-Bra-017226	Brassica rapa	38.79	5.00e-135	474.00
IUUC-Cja-019177	Callithrix jacchus	29.87	3.00e-36	146.00
IUUC-Cfa-020051	Canis familiaris	31.14	5.00e-36	145.00
IUUC-Cpo-021886	Cavia porcellus	29.70	4.00e-38	152.00
IUUC-Cho-024315	Choloepus hoffmanni	47.79	1.00e-17	84.30
IUUC-Dre-028388	Danio rerio	29.34	2.00e-27	117.00
IUUC-Dno-029409	Dasypus novemcinctus	31.14	7.00e-37	148.00
IUUC-Ete-032807	Echinops telfairi	25.71	9.00e-28	118.00
IUUC-Eca-033479	Equus caballus	29.95	2.00e-35	144.00
IUUC-Fca-036320	Felis catus	31.44	3.00e-36	146.00
IUUC-Gma-044402	Glycine max	42.97	0.00e+00	666.00
IUUC-Ggo-045598	Gorilla gorilla	30.23	3.00e-35	143.00
IUUC-Hsa-046598	Homo sapiens	30.23	3.00e-35	143.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	30.21	7.00e-37	148.00
IUUC-Laf-053732	Loxodonta africana	29.72	5.00e-36	145.00
IUUC-Mcc-054661	Macaca mulatta	29.46	2.00e-35	144.00
IUUC-Mtr-057945	Medicago truncatula	55.15	2.00e-103	369.00
IUUC-Mla-059026	Melampsora laricipopulina	37.04	5.00e-17	82.00
IUUC-Mmr-061747	Microcebus murinus	29.69	3.00e-36	146.00
IUUC-Mpu-066339	Mustela putorius furo	30.63	3.00e-35	142.00
IUUC-Mlu-067511	Myotis lucifugus	30.85	2.00e-36	146.00
IUUC-Ola-086795	Oryzias latipes	27.46	3.00e-32	132.00
IUUC-Oga-088713	Otolemur garnettii	30.63	7.00e-37	148.00
IUUC-Oar-089971	Ovis aries	28.50	2.00e-33	137.00
IUUC-Ptr-091670	Pan troglodytes	30.23	4.00e-35	142.00
IUUC-Pan-092293	Papio anubis	29.46	2.00e-35	144.00
IUUC-Psi-093101	Pelodiscus sinensis	31.44	3.00e-36	146.00
IUUC-Pop-099588	Populus trichocarpa	45.23	0.00e+00	677.00
IUUC-Ppe-101794	Prunus persica	45.98	5.00e-135	474.00
IUUC-Stu-112499	Solanum tuberosum	88.61	0.00e+00	1698.00
IUUC-Sar-113530	Sorex araneus	30.77	4.00e-36	145.00
IUUC-Sbi-113785	Sorghum bicolor	31.59	4.00e-52	199.00
IUUC-Ssc-116091	Sus scrofa	29.64	2.00e-34	140.00
IUUC-Ttr-128271	Tursiops truncatus	29.37	1.00e-35	144.00
IUUC-Vpa-130674	Vicugna pacos	29.64	2.00e-35	143.00
IUUC-Xtr-131869	Xenopus tropicalis	31.01	6.00e-38	152.00
IUUC-Xma-133100	Xiphophorus maculatus	32.77	1.00e-34	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence