iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027713

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase znrf1; RING-type E3 ubiquitin transferase znrf1; Zinc/RING finger protein 1

Genbank Nucleotide ID

BC063239

Gene Name

znrf1; zgc:77896

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000020475.8	ENSDART00000010495.6	ENSDARP00000026082.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	76.21	1.00e-93	339.00	IUUC-Hsa-046894

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Functional Description
(View)

E3 ubiquitin-protein ligase that plays a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity.

Protein Sequence
(Fasta)

MGGKQSTAGR PRGAFPGVST DDSAVPPSAH FGHYRPGGTM GLRSRSVSSV AGMGIDHSAT 60
VPFGFYTPRG TDSDRAGGGS GSDPAHNGNG YQETGGGHHT DGMLYLGSRA SLADTLPLHI 120

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Nucleotide Sequence
(Fasta)

CAGCAACACA GCAGCGCACG GACGGATCTG CGCGTGCAGG GGAGCGGCAC ACGCTGACCC 60
GAATCTCCAG GCAGACGGAC GGAGGACGAG CGGACCTGGA CCTAACACTG GACCGGGCAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0449--Lipoprotein
KW-0458--Lysosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005768--C:endosome
GO:0005764--C:lysosome
GO:0016020--C:membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

KEGG

dre:393844

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004093	Anas platyrhynchos	90.00	2.00e-57	213.00
IUUC-Acl-008261	Aspergillus clavatus	50.00	9.00e-10	58.50
IUUC-Afl-008724	Aspergillus flavus	52.27	2.00e-10	60.50
IUUC-Afu-008835	Aspergillus fumigatus	44.44	1.00e-09	58.20
IUUC-Ang-009666	Aspergillus niger	46.30	7.00e-11	62.40
IUUC-Ate-010331	Aspergillus terreus	50.00	1.00e-09	58.20
IUUC-Bgr-012049	Blumeria graminis	43.48	9.00e-07	48.90
IUUC-Bta-012934	Bos taurus	80.18	3.00e-98	350.00
IUUC-Cel-018347	Caenorhabditis elegans	61.18	2.00e-31	128.00
IUUC-Cja-019419	Callithrix jacchus	81.50	1.00e-99	355.00
IUUC-Cfa-020388	Canis familiaris	83.70	1.00e-84	305.00
IUUC-Cpo-021584	Cavia porcellus	81.94	4.00e-100	357.00
IUUC-Cin-025162	Ciona intestinalis	54.46	4.00e-34	137.00
IUUC-Cgl-026728	Colletotrichum gloeosporioides	52.00	2.00e-09	57.40
IUUC-Dse-031322	Dothistroma septosporum	46.81	5.00e-09	56.20
IUUC-Dme-031584	Drosophila melanogaster	65.42	5.00e-38	151.00
IUUC-Eca-033414	Equus caballus	91.15	1.00e-61	227.00
IUUC-Fca-036570	Felis catus	81.94	2.00e-100	357.00
IUUC-Fal-037096	Ficedula albicollis	86.76	3.00e-68	250.00
IUUC-Fso-038176	Fusarium solani	51.02	3.00e-08	54.30
IUUC-Ggr-039766	Gaeumannomyces graminis	45.16	7.00e-09	55.80
IUUC-Gga-041242	Gallus gallus	76.55	3.00e-82	297.00
IUUC-Hsa-046894	Homo sapiens	81.94	3.00e-100	357.00
IUUC-Itr-048339	Ictidomys tridecemlineatus	90.59	1.00e-45	173.00
IUUC-Lch-049749	Latimeria chalumnae	66.19	5.00e-39	153.00
IUUC-Loc-052268	Lepisosteus oculatus	86.51	6.00e-105	373.00
IUUC-Laf-054263	Loxodonta africana	81.94	5.00e-100	357.00
IUUC-Mpo-057355	Magnaporthe poae	45.16	6.00e-09	56.20
IUUC-Mga-059226	Meleagris gallopavo	91.76	8.00e-46	174.00
IUUC-Mmr-061658	Microcebus murinus	81.40	4.00e-42	161.00
IUUC-Mmu-064275	Mus musculus	81.50	2.00e-99	355.00
IUUC-Mpu-066334	Mustela putorius furo	81.94	2.00e-100	357.00
IUUC-Mlu-067491	Myotis lucifugus	80.26	5.00e-97	347.00
IUUC-Nfi-068593	Neosartorya fischeri	44.44	8.00e-10	58.90
IUUC-Ncr-068662	Neurospora crassa	48.98	4.00e-09	57.00
IUUC-Ont-071907	Oreochromis niloticus	90.32	4.00e-97	347.00
IUUC-Oan-072941	Ornithorhynchus anatinus	81.48	3.00e-36	142.00
IUUC-Ocu-074256	Oryctolagus cuniculus	80.70	3.00e-97	347.00
IUUC-Ola-087551	Oryzias latipes	98.85	3.00e-49	186.00
IUUC-Psi-093749	Pelodiscus sinensis	80.00	2.00e-41	159.00
IUUC-Pma-094361	Petromyzon marinus	70.33	1.00e-38	150.00
IUUC-Pfo-097234	Poecilia formosa	91.71	9.00e-105	372.00
IUUC-Pab-098719	Pongo abelii	81.94	3.00e-100	357.00
IUUC-Pva-102216	Pteropus vampyrus	81.18	2.00e-41	162.00
IUUC-Pyt-104423	Pyrenophora triticirepentis	46.67	5.00e-08	52.80
IUUC-Rno-105985	Rattus norvegicus	81.94	6.00e-100	356.00
IUUC-Ssl-108602	Sclerotinia sclerotiorum	48.00	6.00e-08	52.40
IUUC-Ssc-116023	Sus scrofa	81.40	8.00e-42	160.00
IUUC-Tgu-116682	Taeniopygia guttata	72.88	7.00e-71	259.00
IUUC-Tre-122233	Trichoderma reesei	29.29	2.00e-06	47.80
IUUC-Tme-127002	Tuber melanosporum	58.33	4.00e-11	62.80
IUUC-Vda-129847	Verticillium dahliae	52.00	3.00e-09	57.00
IUUC-Xtr-132972	Xenopus tropicalis	68.37	4.00e-62	230.00
IUUC-Xma-134213	Xiphophorus maculatus	91.67	7.00e-104	369.00
IUUC-Yli-134502	Yarrowia lipolytica	31.97	1.00e-13	70.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence