iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054566

Ensembl Protein ID

ENSLAFP00000007493.2

UniProt Accession

G3T2S8; G3T2S8_LOXAF

Protein Name

Coronin

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000008929.2	ENSLAFT00000008926.2	ENSLAFP00000007493.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-16	60.5	80	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d  ++sGs D+t++vW 
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQ 111
           8***********977799*************7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPRFLAV IVEASGGGAF 60
LVLPLGKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLSSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTTCC GCAAAGTGGT TCGGCAGAGC AAGTTCCGGC ATGTGTTCGG ACAGCCGGTC 60
AAGAATGACC AGTGCTACGA GGACATTCGA GTGTCCCGTG TCACCTGGGA CAGCACGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

KEGG

lav:100673226

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	92.64	0.00e+00	923.00
IUUC-Aca-005056	Anolis carolinensis	81.02	0.00e+00	813.00
IUUC-Bta-012984	Bos taurus	91.79	0.00e+00	914.00
IUUC-Cja-019498	Callithrix jacchus	91.43	0.00e+00	911.00
IUUC-Cfa-020937	Canis familiaris	96.25	0.00e+00	858.00
IUUC-Cpo-021866	Cavia porcellus	89.73	0.00e+00	889.00
IUUC-Csa-023561	Chlorocebus sabaeus	92.64	0.00e+00	924.00
IUUC-Dno-029770	Dasypus novemcinctus	87.12	0.00e+00	861.00
IUUC-Dor-030989	Dipodomys ordii	92.20	0.00e+00	899.00
IUUC-Eca-033901	Equus caballus	93.46	0.00e+00	905.00
IUUC-Fca-036494	Felis catus	93.46	0.00e+00	897.00
IUUC-Fal-036737	Ficedula albicollis	82.17	0.00e+00	830.00
IUUC-Ggo-045035	Gorilla gorilla	92.64	0.00e+00	920.00
IUUC-Hsa-046154	Homo sapiens	92.43	0.00e+00	919.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	92.40	0.00e+00	894.00
IUUC-Mcc-054879	Macaca mulatta	92.43	0.00e+00	922.00
IUUC-Mmr-060910	Microcebus murinus	91.58	0.00e+00	917.00
IUUC-Mmu-063455	Mus musculus	92.39	0.00e+00	922.00
IUUC-Mpu-066350	Mustela putorius furo	92.02	0.00e+00	909.00
IUUC-Mlu-067353	Myotis lucifugus	93.00	0.00e+00	903.00
IUUC-Nle-069161	Nomascus leucogenys	92.64	0.00e+00	915.00
IUUC-Opr-071106	Ochotona princeps	91.58	0.00e+00	901.00
IUUC-Oga-088805	Otolemur garnettii	92.64	0.00e+00	925.00
IUUC-Ptr-091484	Pan troglodytes	92.43	0.00e+00	919.00
IUUC-Pan-091843	Papio anubis	92.02	0.00e+00	914.00
IUUC-Pab-097835	Pongo abelii	92.64	0.00e+00	920.00
IUUC-Pca-100411	Procavia capensis	84.19	0.00e+00	815.00
IUUC-Pva-102659	Pteropus vampyrus	93.25	0.00e+00	916.00
IUUC-Rno-106070	Rattus norvegicus	90.97	0.00e+00	912.00
IUUC-Sha-106609	Sarcophilus harrisii	93.80	0.00e+00	709.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence