iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049393

Ensembl Protein ID

CAY68759

UniProt Accession

C4QZT5; C4QZT5_KOMPG

Genbank Protein ID

CAY68759.1

Protein Name

Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylat)

Genbank Nucleotide ID

FN392320

Gene Name

PAS_chr2-1_0152

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr2-1_0152	CAY68759	CAY68759

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.40e-88	295.2	27	214

Active Site

Position(s)	Description	Evidence
198	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfd 111
           e  ++++s+k+l++GagglGcE+lKnL l+G++ i+v+Dmdt++++nlnrqFLfr +d+gksKA+va +++ ++ p+v++++h ++i+++++   F+++f+
   Q: 27   ETFNAIRSSKILVIGAGGLGCEILKNLSLSGFQDIHVIDMDTIDLTNLNRQFLFRNKDIGKSKAKVASQFVMNRIPNVQITPHFCRIQDKDDL--FYRQFQ 125
           66799*************************************************************************************999..****** PP
   S: 112  vVvlaldnrearrkvnrlclna........rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewa 190
           +V+++ld+ earr++n  ++ +         +p+i++gt+G+ Gq r i++ l  c +cs    p+++t+P+ct+++tp+ +eh+iewa
   Q: 126  LVICGLDSTEARRWINHKLVTLldpndfssLIPMIDGGTEGFRGQSRLILPTLSSCFECSLdmIPTNVTYPVCTIANTPRLPEHCIEWA 214
           *************************************************************999************************9 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSINSIKPFT EKKGPFTDDV YEPNTEETFN AIRSSKILVI GAGGLGCEIL KNLSLSGFQD 60
IHVIDMDTID LTNLNRQFLF RNKDIGKSKA KVASQFVMNR IPNVQITPHF CRIQDKDDLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCATTA ACTCAATCAA ACCATTTACG GAGAAGAAGG GTCCATTCAC AGACGATGTT 60
TACGAGCCTA ATACGGAAGA AACATTCAAT GCCATCAGAA GTTCAAAAAT CCTAGTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

ppa:PAS_chr2-1_0152

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	51.50	6.00e-71	258.00
IUUC-Aml-001578	Ailuropoda melanoleuca	54.10	3.00e-111	392.00
IUUC-Atr-002591	Amborella trichopoda	51.25	2.00e-74	271.00
IUUC-Apl-003671	Anas platyrhynchos	54.10	6.00e-110	388.00
IUUC-Aca-004749	Anolis carolinensis	54.10	7.00e-110	388.00
IUUC-Aly-005747	Arabidopsis lyrata	52.03	5.00e-83	299.00
IUUC-Ath-006623	Arabidopsis thaliana	52.36	2.00e-83	300.00
IUUC-Ago-007934	Ashbya gossypii	44.23	2.00e-75	273.00
IUUC-Acl-008047	Aspergillus clavatus	61.90	2.00e-120	423.00
IUUC-Afl-008615	Aspergillus flavus	49.84	9.00e-75	271.00
IUUC-Afu-008996	Aspergillus fumigatus	60.95	4.00e-112	395.00
IUUC-Ani-009281	Aspergillus nidulans	51.43	2.00e-77	280.00
IUUC-Ang-009539	Aspergillus niger	62.22	1.00e-108	384.00
IUUC-Aor-010151	Aspergillus oryzae	59.64	1.00e-106	377.00
IUUC-Ate-010502	Aspergillus terreus	62.86	2.00e-111	394.00
IUUC-Ame-011837	Astyanax mexicanus	52.29	6.00e-98	348.00
IUUC-Bgr-012068	Blumeria graminis	60.71	3.00e-107	379.00
IUUC-Bta-013003	Bos taurus	54.41	1.00e-111	394.00
IUUC-Bci-013983	Botrytis cinerea	63.32	4.00e-111	392.00
IUUC-Bdi-014429	Brachypodium distachyon	51.60	4.00e-76	276.00
IUUC-Bol-015490	Brassica oleracea	51.60	1.00e-74	271.00
IUUC-Bra-018023	Brassica rapa	50.18	3.00e-74	270.00
IUUC-Cel-018684	Caenorhabditis elegans	50.45	1.00e-96	344.00
IUUC-Cja-019200	Callithrix jacchus	54.38	1.00e-109	387.00
IUUC-Cfa-021038	Canis familiaris	54.41	8.00e-112	395.00
IUUC-Cpo-021842	Cavia porcellus	41.71	3.00e-35	141.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	50.31	3.00e-94	336.00
IUUC-Csa-024079	Chlorocebus sabaeus	54.71	2.00e-112	397.00
IUUC-Cho-025052	Choloepus hoffmanni	49.54	3.00e-96	343.00
IUUC-Cin-025113	Ciona intestinalis	51.20	1.00e-93	334.00
IUUC-Csv-026231	Ciona savignyi	50.30	2.00e-97	347.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	62.62	8.00e-109	385.00
IUUC-Cne-026850	Cryptococcus neoformans	61.73	1.00e-114	404.00
IUUC-Cme-027275	Cyanidioschyzon merolae	37.87	4.00e-61	226.00
IUUC-Dre-028751	Danio rerio	52.89	3.00e-99	353.00
IUUC-Dno-029571	Dasypus novemcinctus	55.02	6.00e-112	395.00
IUUC-Dor-030395	Dipodomys ordii	55.02	5.00e-113	399.00
IUUC-Dse-031329	Dothistroma septosporum	55.39	2.00e-102	363.00
IUUC-Dme-031776	Drosophila melanogaster	50.30	1.00e-94	338.00
IUUC-Ete-032894	Echinops telfairi	46.54	6.00e-38	149.00
IUUC-Eca-034389	Equus caballus	54.41	9.00e-112	394.00
IUUC-Eeu-035152	Erinaceus europaeus	49.01	2.00e-83	300.00
IUUC-Fca-036032	Felis catus	54.41	5.00e-112	395.00
IUUC-Fal-037506	Ficedula albicollis	53.80	3.00e-109	386.00
IUUC-Fox-037871	Fusarium oxysporum	59.86	3.00e-90	323.00
IUUC-Fso-038350	Fusarium solani	58.57	2.00e-100	357.00
IUUC-Gmo-039647	Gadus morhua	52.71	2.00e-99	353.00
IUUC-Ggr-039859	Gaeumannomyces graminis	62.46	3.00e-108	383.00
IUUC-Gga-040843	Gallus gallus	51.06	2.00e-100	357.00
IUUC-Gac-042601	Gasterosteus aculeatus	53.80	7.00e-101	358.00
IUUC-Gma-043031	Glycine max	51.25	3.00e-75	273.00
IUUC-Ggo-044788	Gorilla gorilla	54.55	4.00e-111	392.00
IUUC-Hsa-045849	Homo sapiens	54.71	2.00e-112	396.00
IUUC-Hvu-047819	Hordeum vulgare	52.67	1.00e-76	277.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	54.10	4.00e-111	392.00
IUUC-Lch-049471	Latimeria chalumnae	53.80	6.00e-102	362.00
IUUC-Lpe-051297	Leersia perrieri	51.96	6.00e-85	305.00
IUUC-Loc-052910	Lepisosteus oculatus	53.64	2.00e-100	357.00
IUUC-Lma-053181	Leptosphaeria maculans	58.77	4.00e-113	399.00
IUUC-Laf-054314	Loxodonta africana	53.89	5.00e-110	389.00
IUUC-Mcc-054870	Macaca mulatta	54.71	2.00e-112	396.00
IUUC-Meu-056574	Macropus eugenii	45.71	4.00e-45	173.00
IUUC-Mor-056919	Magnaporthe oryzae	59.94	1.00e-106	377.00
IUUC-Mpo-057614	Magnaporthe poae	62.19	2.00e-103	367.00
IUUC-Mtr-058110	Medicago truncatula	50.18	3.00e-73	266.00
IUUC-Mla-058949	Melampsora laricipopulina	61.83	2.00e-114	404.00
IUUC-Mga-059455	Meleagris gallopavo	53.80	6.00e-109	385.00
IUUC-Mvi-060270	Microbotryum violaceum	61.32	4.00e-117	412.00
IUUC-Mmr-061155	Microcebus murinus	53.68	4.00e-108	382.00
IUUC-Mdo-062037	Monodelphis domestica	55.93	8.00e-114	401.00
IUUC-Mmu-063670	Mus musculus	54.41	3.00e-112	396.00
IUUC-Mac-064711	Musa acuminata	52.67	6.00e-75	272.00
IUUC-Mpu-066734	Mustela putorius furo	54.08	4.00e-111	392.00
IUUC-Mlu-067068	Myotis lucifugus	54.71	6.00e-113	398.00
IUUC-Nfi-068349	Neosartorya fischeri	61.59	1.00e-113	400.00
IUUC-Ncr-068626	Neurospora crassa	61.94	6.00e-102	362.00
IUUC-Nle-069366	Nomascus leucogenys	54.71	1.00e-111	394.00
IUUC-Opr-071038	Ochotona princeps	41.55	2.00e-41	161.00
IUUC-Ont-072196	Oreochromis niloticus	53.05	5.00e-100	355.00
IUUC-Oan-073511	Ornithorhynchus anatinus	54.71	3.00e-111	393.00
IUUC-Ocu-073773	Oryctolagus cuniculus	54.71	3.00e-112	396.00
IUUC-Oba-075726	Oryza barthii	46.18	8.00e-74	268.00
IUUC-Obr-076286	Oryza brachyantha	50.89	1.00e-84	304.00
IUUC-Ogl-077686	Oryza glaberrima	43.35	3.00e-48	184.00
IUUC-Ogu-078473	Oryza glumaepatula	46.18	6.00e-74	269.00
IUUC-Oin-079393	Oryza indica	52.67	4.00e-87	312.00
IUUC-Olo-080446	Oryza longistaminata	49.47	3.00e-77	280.00
IUUC-Ome-081737	Oryza meridionalis	49.47	2.00e-77	280.00
IUUC-Oni-082853	Oryza nivara	46.18	8.00e-74	268.00
IUUC-Opu-083590	Oryza punctata	52.67	8.00e-87	311.00
IUUC-Oru-084184	Oryza rufipogon	46.18	8.00e-74	268.00
IUUC-Osa-085402	Oryza sativa	52.67	4.00e-87	312.00
IUUC-Ola-086671	Oryzias latipes	51.22	4.00e-91	325.00
IUUC-Olu-087738	Ostreococcus lucimarinus	46.93	8.00e-77	278.00
IUUC-Oga-088101	Otolemur garnettii	54.10	1.00e-111	394.00
IUUC-Oar-090293	Ovis aries	53.59	1.00e-109	387.00
IUUC-Ptr-090503	Pan troglodytes	54.71	2.00e-112	396.00
IUUC-Pan-092477	Papio anubis	53.78	2.00e-108	384.00
IUUC-Psi-093442	Pelodiscus sinensis	53.80	2.00e-110	390.00
IUUC-Pma-094247	Petromyzon marinus	53.78	4.00e-100	356.00
IUUC-Pno-094780	Phaeosphaeria nodorum	58.52	8.00e-114	401.00
IUUC-Ppa-095338	Physcomitrella patens	49.84	2.00e-97	347.00
IUUC-Pfo-097137	Poecilia formosa	53.66	1.00e-100	357.00
IUUC-Pab-098060	Pongo abelii	54.41	6.00e-104	369.00
IUUC-Pop-099914	Populus trichocarpa	49.37	3.00e-82	296.00
IUUC-Pca-100500	Procavia capensis	39.51	4.00e-72	263.00
IUUC-Ppe-102008	Prunus persica	49.47	5.00e-73	265.00
IUUC-Pva-103095	Pteropus vampyrus	57.59	1.00e-66	244.00
IUUC-Pgr-103666	Puccinia graminis	62.58	2.00e-116	410.00
IUUC-Ptt-103901	Puccinia triticina	64.67	1.00e-121	428.00
IUUC-Pte-104198	Pyrenophora teres	59.01	5.00e-112	395.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	58.44	3.00e-109	386.00
IUUC-Rno-105446	Rattus norvegicus	54.41	2.00e-112	396.00
IUUC-Sce-106355	Saccharomyces cerevisiae	43.71	6.00e-74	268.00
IUUC-Sha-106664	Sarcophilus harrisii	55.32	1.00e-112	397.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	55.65	3.00e-113	399.00
IUUC-Spo-108345	Schizosaccharomyces pombe	54.30	1.00e-110	390.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	59.25	5.00e-96	342.00
IUUC-Smo-109098	Selaginella moellendorffii	56.52	1.00e-101	361.00
IUUC-Sit-109724	Setaria italica	53.02	1.00e-77	281.00
IUUC-Sly-110916	Solanum lycopersicum	48.02	1.00e-81	294.00
IUUC-Stu-112236	Solanum tuberosum	48.33	4.00e-82	296.00
IUUC-Sar-113044	Sorex araneus	55.85	2.00e-105	374.00
IUUC-Sbi-114276	Sorghum bicolor	53.02	3.00e-77	280.00
IUUC-Sre-114963	Sporisorium reilianum	61.80	2.00e-113	400.00
IUUC-Ssc-116301	Sus scrofa	53.59	4.00e-110	389.00
IUUC-Tgu-117265	Taeniopygia guttata	53.50	8.00e-109	385.00
IUUC-Tru-117526	Takifugu rubripes	53.19	1.00e-99	354.00
IUUC-Tsy-119483	Tarsius syrichta	54.40	2.00e-108	384.00
IUUC-Tni-120363	Tetraodon nigroviridis	53.96	1.00e-102	364.00
IUUC-Tca-121731	Theobroma cacao	50.18	3.00e-73	266.00
IUUC-Tre-122221	Trichoderma reesei	59.86	3.00e-91	326.00
IUUC-Tvi-122352	Trichoderma virens	57.81	8.00e-101	358.00
IUUC-Tae-123864	Triticum aestivum	52.31	5.00e-77	279.00
IUUC-Tur-126070	Triticum urartu	49.40	6.00e-62	229.00
IUUC-Tme-127199	Tuber melanosporum	66.43	3.00e-109	385.00
IUUC-Tbe-128076	Tupaia belangeri	54.10	1.00e-111	394.00
IUUC-Ttr-128695	Tursiops truncatus	60.99	2.00e-50	191.00
IUUC-Uma-129638	Ustilago maydis	61.01	6.00e-114	401.00
IUUC-Vda-129963	Verticillium dahliae	61.20	1.00e-98	351.00
IUUC-Vpa-130637	Vicugna pacos	49.09	4.00e-94	335.00
IUUC-Vvi-131613	Vitis vinifera	49.82	9.00e-74	268.00
IUUC-Xtr-132924	Xenopus tropicalis	53.80	2.00e-102	363.00
IUUC-Xma-133356	Xiphophorus maculatus	53.96	1.00e-101	360.00
IUUC-Yli-134365	Yarrowia lipolytica	61.80	5.00e-109	385.00
IUUC-Zma-135941	Zea mays	52.31	2.00e-77	280.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence