iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074080

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02068755

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000001464.3	ENSOCUT00000001465.3	ENSOCUP00000001260.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.30e-138	461.4	126	537

Active Site

Position(s)	Description	Evidence
289	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ +++p+ n+ a+++si++
   Q: 126  ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPKANIIAYHDSIMN 214
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 215  PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 303
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 304  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 390
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 391  krkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQVLDVKSYaslfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 476
           ****************999999********************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 477  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 537
           **********.***********************************************9965 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSVFCLDDVS CSFREEVWEF KPWTNKAAPI GSGSLNAGLC KTPPAASTAR APQHRALGAA 60
RVSRARLASS RAAVRGAPPG GRSAQERKSR RPSPTRFRRR LSSPASDSAA ARGRPAMALS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTTT TTTGTTTGGA TGATGTTTCT TGCTCCTTTA GGGAGGAAGT CTGGGAGTTC 60
AAACCCTGGA CTAACAAGGC CGCCCCTATA GGCTCCGGAA GCCTGAATGC GGGTCTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.26	8.00e-108	384.00
IUUC-Aml-001662	Ailuropoda melanoleuca	97.04	0.00e+00	1241.00
IUUC-Atr-002636	Amborella trichopoda	40.23	2.00e-112	399.00
IUUC-Apl-003369	Anas platyrhynchos	88.38	0.00e+00	1018.00
IUUC-Aca-004490	Anolis carolinensis	83.15	0.00e+00	918.00
IUUC-Aly-006359	Arabidopsis lyrata	42.20	8.00e-105	374.00
IUUC-Ath-007667	Arabidopsis thaliana	42.75	2.00e-108	386.00
IUUC-Ago-007844	Ashbya gossypii	38.07	1.00e-83	303.00
IUUC-Acl-008270	Aspergillus clavatus	43.17	2.00e-105	376.00
IUUC-Afl-008674	Aspergillus flavus	43.93	5.00e-113	401.00
IUUC-Afu-008883	Aspergillus fumigatus	41.64	4.00e-107	382.00
IUUC-Ani-009500	Aspergillus nidulans	45.16	3.00e-117	415.00
IUUC-Ang-009535	Aspergillus niger	43.65	2.00e-111	396.00
IUUC-Aor-010223	Aspergillus oryzae	44.24	1.00e-114	407.00
IUUC-Ate-010282	Aspergillus terreus	43.93	2.00e-90	326.00
IUUC-Ame-011736	Astyanax mexicanus	77.29	0.00e+00	983.00
IUUC-Bgr-012166	Blumeria graminis	42.26	2.00e-99	356.00
IUUC-Bta-012589	Bos taurus	97.19	0.00e+00	1246.00
IUUC-Bci-013802	Botrytis cinerea	42.16	2.00e-101	363.00
IUUC-Bdi-014697	Brachypodium distachyon	41.58	7.00e-112	397.00
IUUC-Bol-016315	Brassica oleracea	42.47	2.00e-110	392.00
IUUC-Bra-017009	Brassica rapa	40.21	4.00e-111	395.00
IUUC-Cel-018708	Caenorhabditis elegans	46.48	2.00e-132	466.00
IUUC-Cja-019120	Callithrix jacchus	97.19	0.00e+00	1199.00
IUUC-Cfa-021061	Canis familiaris	97.50	0.00e+00	1249.00
IUUC-Cpo-021842	Cavia porcellus	96.09	0.00e+00	1191.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.19	0.00e+00	1168.00
IUUC-Cho-024332	Choloepus hoffmanni	86.70	0.00e+00	875.00
IUUC-Cin-025363	Ciona intestinalis	57.00	0.00e+00	684.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.33	7.00e-99	354.00
IUUC-Cne-026888	Cryptococcus neoformans	51.97	5.00e-73	268.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.20	2.00e-59	223.00
IUUC-Dre-028420	Danio rerio	74.53	0.00e+00	916.00
IUUC-Dno-030041	Dasypus novemcinctus	96.72	0.00e+00	1201.00
IUUC-Dor-031039	Dipodomys ordii	82.03	0.00e+00	644.00
IUUC-Dse-031504	Dothistroma septosporum	37.79	2.00e-94	340.00
IUUC-Dme-031771	Drosophila melanogaster	50.00	9.00e-149	520.00
IUUC-Ete-033037	Echinops telfairi	91.56	0.00e+00	1083.00
IUUC-Eca-033774	Equus caballus	97.47	0.00e+00	1200.00
IUUC-Eeu-035074	Erinaceus europaeus	96.10	0.00e+00	963.00
IUUC-Fca-036508	Felis catus	97.47	0.00e+00	1202.00
IUUC-Fal-036813	Ficedula albicollis	86.88	0.00e+00	1016.00
IUUC-Fox-038056	Fusarium oxysporum	43.76	1.00e-106	380.00
IUUC-Fso-038223	Fusarium solani	42.24	8.00e-105	374.00
IUUC-Gmo-038526	Gadus morhua	74.73	0.00e+00	897.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.74	1.00e-100	360.00
IUUC-Gga-040981	Gallus gallus	87.21	0.00e+00	1043.00
IUUC-Gac-041437	Gasterosteus aculeatus	76.18	0.00e+00	923.00
IUUC-Gma-044072	Glycine max	37.91	3.00e-112	399.00
IUUC-Ggo-045358	Gorilla gorilla	93.81	0.00e+00	1112.00
IUUC-Hsa-046068	Homo sapiens	97.34	0.00e+00	1173.00
IUUC-Hvu-047646	Hordeum vulgare	37.99	1.00e-107	383.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.57	0.00e+00	1195.00
IUUC-Lch-049565	Latimeria chalumnae	81.18	0.00e+00	1037.00
IUUC-Lpe-050884	Leersia perrieri	40.64	2.00e-108	386.00
IUUC-Loc-052493	Lepisosteus oculatus	80.82	0.00e+00	1020.00
IUUC-Lma-053117	Leptosphaeria maculans	43.99	8.00e-102	364.00
IUUC-Laf-054518	Loxodonta africana	94.07	0.00e+00	1179.00
IUUC-Mcc-055334	Macaca mulatta	97.03	0.00e+00	1170.00
IUUC-Mor-057137	Magnaporthe oryzae	41.80	4.00e-95	342.00
IUUC-Mpo-057449	Magnaporthe poae	42.38	2.00e-102	366.00
IUUC-Mtr-058045	Medicago truncatula	39.11	5.00e-117	415.00
IUUC-Mla-058864	Melampsora laricipopulina	45.72	6.00e-96	344.00
IUUC-Mga-059422	Meleagris gallopavo	82.38	0.00e+00	922.00
IUUC-Mvi-060536	Microbotryum violaceum	42.39	2.00e-87	316.00
IUUC-Mmr-061161	Microcebus murinus	95.71	0.00e+00	1197.00
IUUC-Mdo-061802	Monodelphis domestica	92.21	0.00e+00	1136.00
IUUC-Mmu-064357	Mus musculus	93.59	0.00e+00	1192.00
IUUC-Mac-065475	Musa acuminata	39.10	2.00e-109	389.00
IUUC-Mpu-066895	Mustela putorius furo	97.50	0.00e+00	1248.00
IUUC-Mlu-067862	Myotis lucifugus	96.26	0.00e+00	1236.00
IUUC-Nfi-068385	Neosartorya fischeri	44.02	2.00e-110	392.00
IUUC-Ncr-068885	Neurospora crassa	41.50	2.00e-107	382.00
IUUC-Nle-069524	Nomascus leucogenys	96.56	0.00e+00	1155.00
IUUC-Opr-071038	Ochotona princeps	96.88	0.00e+00	1241.00
IUUC-Ont-071719	Oreochromis niloticus	75.95	0.00e+00	979.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.40	0.00e+00	993.00
IUUC-Oba-075936	Oryza barthii	39.56	3.00e-108	385.00
IUUC-Obr-076841	Oryza brachyantha	40.29	3.00e-110	392.00
IUUC-Ogl-077686	Oryza glaberrima	39.60	5.00e-110	391.00
IUUC-Ogu-078597	Oryza glumaepatula	38.68	3.00e-105	375.00
IUUC-Oin-079791	Oryza indica	39.56	3.00e-108	385.00
IUUC-Olo-081009	Oryza longistaminata	39.56	2.00e-108	386.00
IUUC-Ome-081327	Oryza meridionalis	36.78	1.00e-102	367.00
IUUC-Oni-082334	Oryza nivara	38.71	1.00e-105	377.00
IUUC-Opu-083447	Oryza punctata	38.47	1.00e-109	390.00
IUUC-Oru-084977	Oryza rufipogon	39.56	2.00e-108	386.00
IUUC-Osa-086160	Oryza sativa	43.49	2.00e-95	342.00
IUUC-Ola-087415	Oryzias latipes	76.03	0.00e+00	942.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.93	5.00e-101	361.00
IUUC-Oga-088434	Otolemur garnettii	96.88	0.00e+00	1198.00
IUUC-Oar-089872	Ovis aries	96.97	0.00e+00	1193.00
IUUC-Ptr-091212	Pan troglodytes	97.34	0.00e+00	1173.00
IUUC-Pan-092708	Papio anubis	98.84	3.00e-132	464.00
IUUC-Psi-093703	Pelodiscus sinensis	90.24	0.00e+00	1044.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.53	5.00e-106	378.00
IUUC-Ppa-095963	Physcomitrella patens	43.74	8.00e-108	384.00
IUUC-Pfo-097515	Poecilia formosa	75.51	0.00e+00	929.00
IUUC-Pab-097951	Pongo abelii	97.06	0.00e+00	1018.00
IUUC-Pop-099703	Populus trichocarpa	36.63	7.00e-96	344.00
IUUC-Pca-100426	Procavia capensis	94.84	0.00e+00	1212.00
IUUC-Ppe-101152	Prunus persica	39.05	4.00e-112	398.00
IUUC-Pva-102792	Pteropus vampyrus	92.60	0.00e+00	1153.00
IUUC-Pgr-103592	Puccinia graminis	44.15	3.00e-101	362.00
IUUC-Ptt-103805	Puccinia triticina	41.92	1.00e-86	314.00
IUUC-Pte-104215	Pyrenophora teres	44.77	2.00e-113	402.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	42.10	8.00e-112	397.00
IUUC-Rno-106117	Rattus norvegicus	94.06	0.00e+00	1197.00
IUUC-Sce-106177	Saccharomyces cerevisiae	37.33	6.00e-76	278.00
IUUC-Sha-107006	Sarcophilus harrisii	92.52	0.00e+00	1141.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.96	1.00e-94	340.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.38	4.00e-96	345.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.45	4.00e-104	372.00
IUUC-Smo-109264	Selaginella moellendorffii	43.57	5.00e-107	381.00
IUUC-Sit-110581	Setaria italica	41.28	3.00e-109	389.00
IUUC-Sly-111870	Solanum lycopersicum	39.24	9.00e-112	397.00
IUUC-Stu-112283	Solanum tuberosum	39.54	2.00e-109	389.00
IUUC-Sar-113432	Sorex araneus	71.76	0.00e+00	797.00
IUUC-Sbi-114075	Sorghum bicolor	39.08	4.00e-109	388.00
IUUC-Sre-114926	Sporisorium reilianum	43.22	1.00e-104	373.00
IUUC-Ssc-116281	Sus scrofa	98.62	1.00e-117	414.00
IUUC-Tgu-117247	Taeniopygia guttata	85.21	0.00e+00	1012.00
IUUC-Tru-118075	Takifugu rubripes	71.47	0.00e+00	893.00
IUUC-Tsy-119398	Tarsius syrichta	80.62	0.00e+00	919.00
IUUC-Tni-120771	Tetraodon nigroviridis	67.46	0.00e+00	808.00
IUUC-Tca-121651	Theobroma cacao	38.80	2.00e-110	392.00
IUUC-Tre-122224	Trichoderma reesei	43.62	2.00e-96	347.00
IUUC-Tvi-122634	Trichoderma virens	43.22	4.00e-96	345.00
IUUC-Tae-125665	Triticum aestivum	40.37	7.00e-106	377.00
IUUC-Tur-126417	Triticum urartu	39.42	1.00e-106	380.00
IUUC-Tme-127016	Tuber melanosporum	44.37	9.00e-97	347.00
IUUC-Tbe-127678	Tupaia belangeri	81.46	2.00e-177	615.00
IUUC-Ttr-128598	Tursiops truncatus	93.28	0.00e+00	1184.00
IUUC-Uma-129612	Ustilago maydis	41.59	2.00e-97	349.00
IUUC-Vda-129811	Verticillium dahliae	43.64	9.00e-103	367.00
IUUC-Vpa-130732	Vicugna pacos	83.28	0.00e+00	1025.00
IUUC-Vvi-130832	Vitis vinifera	41.70	2.00e-106	380.00
IUUC-Xtr-132823	Xenopus tropicalis	75.63	0.00e+00	919.00
IUUC-Xma-133552	Xiphophorus maculatus	75.36	0.00e+00	927.00
IUUC-Yli-134666	Yarrowia lipolytica	37.45	2.00e-76	280.00
IUUC-Zma-135547	Zea mays	39.05	3.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence