iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132621

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD repeat-containing protein 37

Genbank Nucleotide ID

AAMC01042513

Gene Name

wdr37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000018083.3	ENSXETT00000039219.2	ENSXETP00000039219.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-24	85.7	366	397
UBD/Beta-Prp	2.80e-44	151.6	280	487

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 366  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 397
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkghe 94
           +h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh+
   Q: 280  SHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGHT 368
           56666666888889999**********************************************************665422889***** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgght 180
           d+v+s  f   gd +vsGs+drt++vwdl++          +d+++n ++v+  +++++  +++r+vrl+d+   + ++l r  ++gh 
   Q: 369  DTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAINRISVSVGQRIIALPHDNRQVRLFDMsgvRLARLPRSNRQGHR 455
           *****99999.********************99887.666677788888888879*****************777778888888888** PP
   S: 181  dsvyslsfdsng..kelvsgsldgtvklwdlq 210
           ++v + +++++     l +++ d++ + w++ 
   Q: 456  RMVCCCAWSEDHptCNLFTCGFDRQAIGWNIN 487
           **********99767789***********986 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MPTESGSWAA ARQTKQKRKS HSLSIKRTNS SEQDRPGLQR EMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYLENLELR REIDTLNDRL AVEGQAIDGA ELSKGQMKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAAATGCCC GGAGCTGGTG GTGGTTCGTG TGTTGGAGAG TGAGGCGGAG GAGGTTGCCC 60
TTGCGACTCG TTGCTGCTTG TGTTGCTGCT GCCGCTCTTC TTTAGCAGAC AGGTAATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	89.72	0.00e+00	906.00
IUUC-Apl-003647	Anas platyrhynchos	92.32	0.00e+00	929.00
IUUC-Aca-004759	Anolis carolinensis	92.53	0.00e+00	944.00
IUUC-Ame-011103	Astyanax mexicanus	56.75	2.00e-145	508.00
IUUC-Bta-012718	Bos taurus	89.72	0.00e+00	903.00
IUUC-Cel-018499	Caenorhabditis elegans	42.61	5.00e-98	351.00
IUUC-Cja-019492	Callithrix jacchus	91.11	0.00e+00	944.00
IUUC-Cfa-020199	Canis familiaris	89.72	0.00e+00	932.00
IUUC-Cpo-022500	Cavia porcellus	84.88	0.00e+00	884.00
IUUC-Csa-023567	Chlorocebus sabaeus	91.72	0.00e+00	950.00
IUUC-Cho-025071	Choloepus hoffmanni	65.05	3.00e-176	611.00
IUUC-Cin-025460	Ciona intestinalis	45.40	8.00e-105	373.00
IUUC-Csv-026042	Ciona savignyi	46.09	6.00e-108	384.00
IUUC-Dre-028214	Danio rerio	85.05	0.00e+00	869.00
IUUC-Dno-029826	Dasypus novemcinctus	93.01	0.00e+00	808.00
IUUC-Dor-030967	Dipodomys ordii	90.71	0.00e+00	846.00
IUUC-Dme-031936	Drosophila melanogaster	49.05	1.00e-118	420.00
IUUC-Ete-032452	Echinops telfairi	89.29	0.00e+00	917.00
IUUC-Eca-033278	Equus caballus	89.72	0.00e+00	932.00
IUUC-Eeu-034592	Erinaceus europaeus	78.18	0.00e+00	780.00
IUUC-Fca-036431	Felis catus	90.14	0.00e+00	934.00
IUUC-Fal-037149	Ficedula albicollis	92.32	0.00e+00	931.00
IUUC-Gmo-038476	Gadus morhua	80.45	0.00e+00	781.00
IUUC-Gga-041099	Gallus gallus	92.73	0.00e+00	933.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.80	0.00e+00	826.00
IUUC-Ggo-044683	Gorilla gorilla	84.24	0.00e+00	858.00
IUUC-Hsa-046658	Homo sapiens	91.31	0.00e+00	942.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	92.75	0.00e+00	885.00
IUUC-Lch-050571	Latimeria chalumnae	86.31	0.00e+00	907.00
IUUC-Loc-052652	Lepisosteus oculatus	83.94	0.00e+00	882.00
IUUC-Laf-053712	Loxodonta africana	90.58	0.00e+00	934.00
IUUC-Mcc-055521	Macaca mulatta	91.72	0.00e+00	950.00
IUUC-Meu-056324	Macropus eugenii	88.48	0.00e+00	874.00
IUUC-Mga-060114	Meleagris gallopavo	92.54	0.00e+00	929.00
IUUC-Mmr-061176	Microcebus murinus	91.52	0.00e+00	948.00
IUUC-Mdo-061888	Monodelphis domestica	92.54	0.00e+00	904.00
IUUC-Mmu-063977	Mus musculus	91.94	0.00e+00	949.00
IUUC-Mpu-066220	Mustela putorius furo	77.27	8.00e-168	582.00
IUUC-Mlu-068155	Myotis lucifugus	91.13	0.00e+00	942.00
IUUC-Nle-069964	Nomascus leucogenys	91.52	0.00e+00	949.00
IUUC-Opr-070925	Ochotona princeps	89.45	5.00e-143	500.00
IUUC-Ont-071317	Oreochromis niloticus	86.90	0.00e+00	856.00
IUUC-Oan-072952	Ornithorhynchus anatinus	92.74	0.00e+00	931.00
IUUC-Ocu-073913	Oryctolagus cuniculus	91.33	0.00e+00	947.00
IUUC-Ola-087024	Oryzias latipes	84.91	0.00e+00	887.00
IUUC-Oga-087945	Otolemur garnettii	90.93	0.00e+00	944.00
IUUC-Oar-089854	Ovis aries	89.72	0.00e+00	897.00
IUUC-Ptr-091486	Pan troglodytes	91.52	0.00e+00	945.00
IUUC-Pan-091738	Papio anubis	91.72	0.00e+00	950.00
IUUC-Psi-093953	Pelodiscus sinensis	92.14	0.00e+00	927.00
IUUC-Pma-094560	Petromyzon marinus	76.63	0.00e+00	788.00
IUUC-Pfo-097222	Poecilia formosa	85.45	0.00e+00	840.00
IUUC-Pab-098778	Pongo abelii	86.67	0.00e+00	883.00
IUUC-Pca-100852	Procavia capensis	87.47	0.00e+00	887.00
IUUC-Pva-103130	Pteropus vampyrus	88.43	6.00e-128	450.00
IUUC-Rno-105848	Rattus norvegicus	83.06	0.00e+00	833.00
IUUC-Sha-106750	Sarcophilus harrisii	92.74	0.00e+00	933.00
IUUC-Sar-113749	Sorex araneus	82.42	0.00e+00	838.00
IUUC-Ssc-115691	Sus scrofa	89.49	0.00e+00	898.00
IUUC-Tgu-117365	Taeniopygia guttata	92.32	0.00e+00	887.00
IUUC-Tru-117595	Takifugu rubripes	84.48	0.00e+00	837.00
IUUC-Tsy-118973	Tarsius syrichta	71.35	4.00e-144	504.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.14	0.00e+00	872.00
IUUC-Tbe-127976	Tupaia belangeri	68.48	0.00e+00	657.00
IUUC-Ttr-128472	Tursiops truncatus	88.08	0.00e+00	899.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence