iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-089175

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03047183

Gene Name

TRIM8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003628.2	ENSOGAT00000003632.2	ENSOGAP00000003231.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.2	15	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl  f + p+ lpC+H f++ C+ ++w     + s+  rCP C+
   Q: 15   CPICLHVFVE-PVQLPCKHNFCRGCIgEAW----AKDSGLVRCPECN 56
           ********99.999****************....889*********7 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKDSGLV RCPECNQAYN 60
QKPGLEKNLK LTNIVEKFNA LHVEKPPAAL HCVFCRRGPP LPAQKVCLRC EAPCCQSHVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCCGCCA TGGCAGAGAA TTGGAAAAAC TGCTTCGAGG AGGAGCTCAT TTGCCCCATC 60
TGCCTGCACG TCTTCGTGGA GCCGGTGCAG CTGCCGTGCA AACACAACTT CTGCCGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001258	Ailuropoda melanoleuca	98.91	0.00e+00	1128.00
IUUC-Apl-004223	Anas platyrhynchos	86.05	0.00e+00	993.00
IUUC-Aca-005106	Anolis carolinensis	86.03	0.00e+00	1019.00
IUUC-Ame-011348	Astyanax mexicanus	66.96	0.00e+00	762.00
IUUC-Bta-012787	Bos taurus	99.64	0.00e+00	1137.00
IUUC-Cja-019471	Callithrix jacchus	99.46	0.00e+00	1135.00
IUUC-Cfa-020052	Canis familiaris	99.09	0.00e+00	1132.00
IUUC-Cpo-022491	Cavia porcellus	96.69	0.00e+00	723.00
IUUC-Csa-023544	Chlorocebus sabaeus	99.46	0.00e+00	1135.00
IUUC-Dre-028013	Danio rerio	66.61	0.00e+00	766.00
IUUC-Dno-029676	Dasypus novemcinctus	98.91	0.00e+00	1132.00
IUUC-Dor-030402	Dipodomys ordii	98.19	0.00e+00	1123.00
IUUC-Ete-033188	Echinops telfairi	90.24	0.00e+00	1019.00
IUUC-Eca-033524	Equus caballus	98.37	0.00e+00	1120.00
IUUC-Eeu-034979	Erinaceus europaeus	98.01	3.00e-144	505.00
IUUC-Fca-036362	Felis catus	99.09	0.00e+00	1130.00
IUUC-Fal-036652	Ficedula albicollis	84.62	0.00e+00	974.00
IUUC-Gmo-039405	Gadus morhua	60.99	0.00e+00	653.00
IUUC-Gga-040813	Gallus gallus	85.84	0.00e+00	994.00
IUUC-Gac-041792	Gasterosteus aculeatus	64.48	0.00e+00	661.00
IUUC-Ggo-044962	Gorilla gorilla	99.46	0.00e+00	1135.00
IUUC-Hsa-046158	Homo sapiens	99.27	0.00e+00	1134.00
IUUC-Itr-048118	Ictidomys tridecemlineatus	99.27	0.00e+00	1132.00
IUUC-Lch-049433	Latimeria chalumnae	80.18	0.00e+00	878.00
IUUC-Loc-052026	Lepisosteus oculatus	76.84	0.00e+00	885.00
IUUC-Laf-054159	Loxodonta africana	97.19	0.00e+00	915.00
IUUC-Mcc-055490	Macaca mulatta	99.46	0.00e+00	1135.00
IUUC-Meu-056549	Macropus eugenii	89.49	0.00e+00	746.00
IUUC-Mga-059334	Meleagris gallopavo	86.03	0.00e+00	991.00
IUUC-Mmr-061672	Microcebus murinus	99.46	0.00e+00	1136.00
IUUC-Mdo-061849	Monodelphis domestica	89.74	0.00e+00	934.00
IUUC-Mmu-063537	Mus musculus	98.00	0.00e+00	1122.00
IUUC-Mpu-065762	Mustela putorius furo	99.27	0.00e+00	1134.00
IUUC-Mlu-066979	Myotis lucifugus	95.62	0.00e+00	757.00
IUUC-Nle-069419	Nomascus leucogenys	99.46	0.00e+00	1135.00
IUUC-Opr-070981	Ochotona princeps	98.55	0.00e+00	1127.00
IUUC-Ont-072053	Oreochromis niloticus	59.22	8.00e-177	613.00
IUUC-Oan-073608	Ornithorhynchus anatinus	87.42	0.00e+00	837.00
IUUC-Ocu-074694	Oryctolagus cuniculus	98.55	0.00e+00	1087.00
IUUC-Ola-086949	Oryzias latipes	60.49	4.00e-177	614.00
IUUC-Oar-089591	Ovis aries	89.08	0.00e+00	890.00
IUUC-Ptr-091309	Pan troglodytes	98.37	0.00e+00	1099.00
IUUC-Pan-091903	Papio anubis	99.46	0.00e+00	1135.00
IUUC-Psi-093293	Pelodiscus sinensis	84.14	0.00e+00	976.00
IUUC-Pfo-097191	Poecilia formosa	60.49	7.00e-174	603.00
IUUC-Pab-098251	Pongo abelii	95.83	0.00e+00	1082.00
IUUC-Pca-100504	Procavia capensis	99.09	0.00e+00	1134.00
IUUC-Pva-102320	Pteropus vampyrus	98.19	0.00e+00	1082.00
IUUC-Rno-105545	Rattus norvegicus	98.19	0.00e+00	1122.00
IUUC-Ssc-116121	Sus scrofa	99.64	0.00e+00	1137.00
IUUC-Tgu-116724	Taeniopygia guttata	85.84	0.00e+00	989.00
IUUC-Tru-118048	Takifugu rubripes	59.59	2.00e-180	625.00
IUUC-Tni-120856	Tetraodon nigroviridis	60.68	7.00e-172	597.00
IUUC-Tbe-127400	Tupaia belangeri	85.83	1.00e-165	575.00
IUUC-Ttr-128233	Tursiops truncatus	98.37	0.00e+00	1110.00
IUUC-Xtr-132578	Xenopus tropicalis	84.39	0.00e+00	974.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence