iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129688

Ensembl Protein ID

EGY15546

UniProt Accession

G2X978; G2X978_VERDV

Genbank Protein ID

EGY15546.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

DS572708

Gene Name

VDAG_06710

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_06710	EGY15546	EGY15546

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.10e-52	175.7	301	779
UBD/Alpha-Helix/UBA	7.10e-17	60.1	592	625

Active Site

Position(s)	Description	Evidence
310	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
737	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel...................wkskkkavsprellkalkkeae 82
           tGlkNlgN+CY+ S++QcL+ +p+++  +++  + +l+    ++p ++l ++l+k+   l                     + +k  +p +l++ +++ + 
   Q: 301  TGLKNLGNSCYLASIIQCLFDMPSFKTRYFQ-PNLDLPVV--EDPAADLETQLRKMADGLhsgryskpdpeapvsdetpHLTYQKGLAPAMLKHLIGRGHA 398
           7******************************.66666665..799***************6666666666666555433366666**************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetk 183
           efs+++qqDa E+l++l++ + ++                            +  + +  ++ F++ l+++++c  c++v  ++++   + ++vp ++  +
   Q: 399  EFSTMRQQDAFELLQHLFKLITRTN---------------------------HPAGLQDPTQQFRFVLEQRLQCTGCKKVRYTTNEQDNIFINVPLEKLPA 472
           ********************99988...........................56777778999******************99999999999***999888 PP
   S: 184  ke............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts.... 267
           +e            +l++cL++ft+ee +e    + c++c +k   +k+  +k+lP+vL+++ k++     ++++ ki+  v +p+e + l+ +++     
   Q: 473  TEdgeakadqyapvTLKECLDNFTAEEAVE----LTCSSCGSKDGYTKRSLFKTLPDVLVVNAKKMAI--INWVPVKIDVPVIVPDEaFPLDAYLSPgvqp 567
           889999999********************9....9*******************************55..67************************99998 PP
   S: 268  ..................................................................................................... 267
                                                                                                                
   Q: 568  geeqlpedaesrapsfepnaeavvqleamgfprnrcekalhatgnasadsamewlfahmedpdidapldlggaaaggdtadpekidmlgamgfgapqakka 668
           88888888888888888888777777777777777777777777777777777777777777666666666666666666666666666666666666655 PP
   S: 268  ..................peekqke............................kkkYeLiavvvHsG.slssGHYvayvknekgk..WllfdDskVtevke 319
                             p     +                            + +++L ++v+H+G s++ GHYva++++  ++  W+lf+D+kV e  e
   Q: 669  lretagdveravewlfshP-----DdqgafddeaaapaaesagpaepagsaavPANFQLQSIVCHKGtSIHAGHYVAFIRQAGDHpsWVLFNDEKVVEAGE 764
           5555555555555555550.....05555555555555555666666666666****************************655578*********99965 PP
   S: 320  .eevleetgstaYvlfYkr 337
            ee+     + aYv+f+kr
   Q: 765  vEEMR----KFAYVYFFKR 779
           24444....68******98 PP

UBD/Alpha-Helix/UBA

   S: 9    qlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ql++MGF+r+++ +aL a+ n +++ A+e+L+ +
   Q: 592  QLEAMGFPRNRCEKALHATgNASADSAMEWLFAH 625
           99*****************************976 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MACPHLDSLT LRPPTAAQSV YREDCTQCFD SIDDPAGLDV CLQCFNGGCA GERNHASLHR 60
ALWSHPLVLN IRRSRKVVVR DEPPFKMSKL AIAAETDEDR YDTKTTVRCL ECSTELDQTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGTC CTCACCTTGA CTCCCTGAGT ACGTCAGCCA CGTTGCAACA ACCGCCTGTC 60
ATCATCTACG TCGATCGTCA CTGACATTGT GCCCCTTGCA GCTCTCAGGC CCCCCACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

vda:VDAG_06710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.91	1.00e-96	345.00
IUUC-Aml-002104	Ailuropoda melanoleuca	33.99	3.00e-126	444.00
IUUC-Atr-002580	Amborella trichopoda	34.49	1.00e-116	412.00
IUUC-Apl-003774	Anas platyrhynchos	33.97	1.00e-120	426.00
IUUC-Aca-005368	Anolis carolinensis	35.02	5.00e-128	450.00
IUUC-Aly-005727	Arabidopsis lyrata	35.52	1.00e-119	422.00
IUUC-Ath-006974	Arabidopsis thaliana	35.64	2.00e-119	421.00
IUUC-Ago-007890	Ashbya gossypii	32.47	2.00e-109	388.00
IUUC-Acl-008057	Aspergillus clavatus	55.76	0.00e+00	865.00
IUUC-Afl-008547	Aspergillus flavus	57.21	0.00e+00	775.00
IUUC-Afu-008805	Aspergillus fumigatus	52.47	0.00e+00	769.00
IUUC-Ani-009441	Aspergillus nidulans	52.33	0.00e+00	712.00
IUUC-Ang-009720	Aspergillus niger	56.83	0.00e+00	887.00
IUUC-Aor-010111	Aspergillus oryzae	58.60	0.00e+00	943.00
IUUC-Ate-010531	Aspergillus terreus	53.88	0.00e+00	808.00
IUUC-Ame-011893	Astyanax mexicanus	35.94	2.00e-106	378.00
IUUC-Bgr-012183	Blumeria graminis	60.23	0.00e+00	952.00
IUUC-Bta-013179	Bos taurus	34.19	9.00e-127	446.00
IUUC-Bci-013858	Botrytis cinerea	66.62	0.00e+00	1084.00
IUUC-Bdi-014904	Brachypodium distachyon	34.07	1.00e-101	362.00
IUUC-Bol-015296	Brassica oleracea	35.11	4.00e-118	417.00
IUUC-Bra-017939	Brassica rapa	34.86	4.00e-118	417.00
IUUC-Cel-018625	Caenorhabditis elegans	30.39	3.00e-80	291.00
IUUC-Cja-019063	Callithrix jacchus	33.37	4.00e-123	434.00
IUUC-Cfa-020976	Canis familiaris	35.36	7.00e-131	459.00
IUUC-Cpo-022265	Cavia porcellus	35.10	2.00e-130	458.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	33.88	3.00e-67	248.00
IUUC-Csa-024177	Chlorocebus sabaeus	35.37	3.00e-119	421.00
IUUC-Cho-024702	Choloepus hoffmanni	31.83	1.00e-75	276.00
IUUC-Cin-025411	Ciona intestinalis	33.94	1.00e-102	365.00
IUUC-Csv-026347	Ciona savignyi	33.21	5.00e-107	380.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	79.62	0.00e+00	1195.00
IUUC-Cne-026831	Cryptococcus neoformans	48.38	0.00e+00	655.00
IUUC-Cme-027335	Cyanidioschyzon merolae	32.90	3.00e-73	268.00
IUUC-Dre-027982	Danio rerio	32.63	2.00e-105	374.00
IUUC-Dno-029034	Dasypus novemcinctus	34.42	7.00e-128	449.00
IUUC-Dor-030479	Dipodomys ordii	34.93	2.00e-57	215.00
IUUC-Dse-031467	Dothistroma septosporum	56.18	0.00e+00	882.00
IUUC-Dme-032075	Drosophila melanogaster	32.66	1.00e-108	385.00
IUUC-Ete-032865	Echinops telfairi	31.03	2.00e-104	371.00
IUUC-Eca-034059	Equus caballus	33.95	1.00e-124	438.00
IUUC-Eeu-035304	Erinaceus europaeus	34.91	3.00e-118	417.00
IUUC-Fca-035515	Felis catus	34.07	2.00e-126	444.00
IUUC-Fal-037271	Ficedula albicollis	35.14	1.00e-118	418.00
IUUC-Fox-037745	Fusarium oxysporum	77.78	0.00e+00	1204.00
IUUC-Fso-038158	Fusarium solani	78.29	0.00e+00	1216.00
IUUC-Gmo-039071	Gadus morhua	34.17	1.00e-111	395.00
IUUC-Ggr-040098	Gaeumannomyces graminis	70.06	0.00e+00	1062.00
IUUC-Gga-040635	Gallus gallus	33.84	1.00e-125	442.00
IUUC-Gac-042528	Gasterosteus aculeatus	35.05	5.00e-113	400.00
IUUC-Gma-043614	Glycine max	34.28	2.00e-109	388.00
IUUC-Ggo-044602	Gorilla gorilla	33.96	9.00e-127	446.00
IUUC-Hsa-045959	Homo sapiens	33.96	9.00e-127	446.00
IUUC-Hvu-047563	Hordeum vulgare	37.12	5.00e-102	363.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.04	2.00e-127	447.00
IUUC-Kpa-049156	Komagataella pastoris	41.92	5.00e-179	619.00
IUUC-Lch-049648	Latimeria chalumnae	34.81	8.00e-120	422.00
IUUC-Lpe-051523	Leersia perrieri	32.97	7.00e-100	356.00
IUUC-Loc-052072	Lepisosteus oculatus	31.09	1.00e-104	372.00
IUUC-Lma-053216	Leptosphaeria maculans	61.74	0.00e+00	937.00
IUUC-Laf-054327	Loxodonta africana	34.07	2.00e-125	441.00
IUUC-Mcc-055443	Macaca mulatta	33.96	5.00e-127	446.00
IUUC-Meu-056298	Macropus eugenii	33.74	3.00e-86	311.00
IUUC-Mor-057106	Magnaporthe oryzae	72.46	0.00e+00	1124.00
IUUC-Mpo-057589	Magnaporthe poae	70.31	0.00e+00	1071.00
IUUC-Mtr-058680	Medicago truncatula	36.42	4.00e-116	410.00
IUUC-Mla-058903	Melampsora laricipopulina	43.76	6.00e-180	622.00
IUUC-Mga-059669	Meleagris gallopavo	33.17	4.00e-118	417.00
IUUC-Mvi-060476	Microbotryum violaceum	44.15	6.00e-176	609.00
IUUC-Mmr-060575	Microcebus murinus	34.07	7.00e-127	446.00
IUUC-Mdo-062183	Monodelphis domestica	34.68	1.00e-128	452.00
IUUC-Mmu-063592	Mus musculus	34.07	3.00e-126	444.00
IUUC-Mac-065634	Musa acuminata	31.95	1.00e-101	362.00
IUUC-Mpu-066082	Mustela putorius furo	35.36	5.00e-131	459.00
IUUC-Mlu-067345	Myotis lucifugus	33.72	9.00e-126	442.00
IUUC-Nfi-068558	Neosartorya fischeri	55.48	0.00e+00	835.00
IUUC-Ncr-068960	Neurospora crassa	69.66	0.00e+00	1053.00
IUUC-Nle-070173	Nomascus leucogenys	35.02	5.00e-130	456.00
IUUC-Opr-070556	Ochotona princeps	34.43	4.00e-128	450.00
IUUC-Ont-071502	Oreochromis niloticus	34.65	4.00e-115	407.00
IUUC-Oan-072959	Ornithorhynchus anatinus	40.51	1.00e-45	174.00
IUUC-Ocu-074861	Oryctolagus cuniculus	35.26	3.00e-130	457.00
IUUC-Oba-075109	Oryza barthii	33.83	1.00e-105	375.00
IUUC-Obr-076292	Oryza brachyantha	33.29	9.00e-100	356.00
IUUC-Ogl-077065	Oryza glaberrima	34.90	1.00e-112	398.00
IUUC-Ogu-078776	Oryza glumaepatula	33.71	1.00e-109	388.00
IUUC-Oin-080048	Oryza indica	34.77	7.00e-112	396.00
IUUC-Olo-080711	Oryza longistaminata	33.63	1.00e-100	358.00
IUUC-Ome-081506	Oryza meridionalis	34.38	1.00e-101	362.00
IUUC-Oni-082320	Oryza nivara	32.65	6.00e-103	366.00
IUUC-Opu-083801	Oryza punctata	33.75	9.00e-101	359.00
IUUC-Oru-085139	Oryza rufipogon	32.89	2.00e-102	365.00
IUUC-Osa-085713	Oryza sativa	35.02	2.00e-113	401.00
IUUC-Ola-086951	Oryzias latipes	34.31	2.00e-107	381.00
IUUC-Olu-087822	Ostreococcus lucimarinus	31.96	5.00e-98	350.00
IUUC-Oga-088625	Otolemur garnettii	33.72	8.00e-127	446.00
IUUC-Oar-089995	Ovis aries	34.11	1.00e-126	445.00
IUUC-Ptr-090640	Pan troglodytes	34.56	6.00e-129	452.00
IUUC-Pan-091974	Papio anubis	33.72	2.00e-126	444.00
IUUC-Psi-093957	Pelodiscus sinensis	34.19	1.00e-128	452.00
IUUC-Pma-094242	Petromyzon marinus	39.90	2.00e-70	257.00
IUUC-Pno-094835	Phaeosphaeria nodorum	61.84	0.00e+00	863.00
IUUC-Ppa-095901	Physcomitrella patens	36.30	6.00e-120	423.00
IUUC-Pfo-097148	Poecilia formosa	35.26	5.00e-116	410.00
IUUC-Pab-098068	Pongo abelii	31.70	2.00e-106	378.00
IUUC-Pop-098943	Populus trichocarpa	34.77	1.00e-114	405.00
IUUC-Pca-100738	Procavia capensis	34.43	2.00e-90	325.00
IUUC-Ppe-101315	Prunus persica	33.70	2.00e-108	385.00
IUUC-Pva-102154	Pteropus vampyrus	33.60	1.00e-122	432.00
IUUC-Pgr-103343	Puccinia graminis	43.53	7.00e-150	522.00
IUUC-Ptt-103928	Puccinia triticina	38.41	2.00e-144	504.00
IUUC-Pte-104306	Pyrenophora teres	61.92	0.00e+00	900.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	61.92	0.00e+00	922.00
IUUC-Rno-105801	Rattus norvegicus	34.19	1.00e-126	445.00
IUUC-Sce-106304	Saccharomyces cerevisiae	33.71	6.00e-114	403.00
IUUC-Sha-107635	Sarcophilus harrisii	34.58	2.00e-129	454.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	42.11	2.00e-171	594.00
IUUC-Spo-108144	Schizosaccharomyces pombe	41.80	9.00e-175	605.00
IUUC-Smo-108703	Selaginella moellendorffii	37.11	3.00e-114	404.00
IUUC-Sit-110728	Setaria italica	33.75	1.00e-112	398.00
IUUC-Sly-111523	Solanum lycopersicum	35.59	6.00e-122	429.00
IUUC-Sar-113733	Sorex araneus	38.26	2.00e-55	208.00
IUUC-Sbi-114419	Sorghum bicolor	34.07	3.00e-108	384.00
IUUC-Sre-115225	Sporisorium reilianum	45.16	0.00e+00	640.00
IUUC-Ssc-115686	Sus scrofa	34.15	1.00e-126	445.00
IUUC-Tgu-117346	Taeniopygia guttata	33.65	5.00e-121	426.00
IUUC-Tru-118350	Takifugu rubripes	32.48	1.00e-107	382.00
IUUC-Tsy-119278	Tarsius syrichta	34.72	7.00e-90	323.00
IUUC-Tni-120658	Tetraodon nigroviridis	34.20	3.00e-107	381.00
IUUC-Tca-121585	Theobroma cacao	34.53	3.00e-110	391.00
IUUC-Tre-122043	Trichoderma reesei	74.58	0.00e+00	1150.00
IUUC-Tvi-122303	Trichoderma virens	73.72	0.00e+00	1145.00
IUUC-Tae-125686	Triticum aestivum	34.28	3.00e-109	387.00
IUUC-Tur-126732	Triticum urartu	32.23	5.00e-99	353.00
IUUC-Tme-126909	Tuber melanosporum	60.45	0.00e+00	910.00
IUUC-Tbe-127261	Tupaia belangeri	30.86	2.00e-72	265.00
IUUC-Ttr-129119	Tursiops truncatus	34.88	1.00e-58	219.00
IUUC-Uma-129599	Ustilago maydis	44.64	0.00e+00	660.00
IUUC-Vpa-130170	Vicugna pacos	30.06	3.00e-77	281.00
IUUC-Vvi-131116	Vitis vinifera	34.96	8.00e-113	399.00
IUUC-Xtr-131953	Xenopus tropicalis	33.25	2.00e-113	401.00
IUUC-Xma-133837	Xiphophorus maculatus	35.26	1.00e-115	408.00
IUUC-Yli-134510	Yarrowia lipolytica	46.67	3.00e-179	620.00
IUUC-Zma-135786	Zea mays	32.92	1.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence