iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096720

Ensembl Protein ID

ENSPFOP00000002233.2

UniProt Accession

A0A087X8Y0; A0A087X8Y0_POEFO

Genbank Protein ID

ENSPFOP00000002233

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01011918

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000002031.2	ENSPFOT00000023428.1	ENSPFOP00000022279.1
ENSPFOG00000002031.2	ENSPFOT00000002237.2	ENSPFOP00000002233.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-73	248.5	524	848

Active Site

Position(s)	Description	Evidence
818	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 8    rlevefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrll 88
            +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+      ++d ++ np  + +  +e++G+l+g al+ + +l
   Q: 524  WWECKFIAEGIIDQGGGFRDSLADMSEELCPSSaecpmpLPFFTRTSNQGDF--EARDYYVPNPscKDFHKYEWIGQLMGAALRGKDFL 610
           356*****************************99999888888777774444..566666666666899******************** PP
   S: 89   dlplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfs...vseeilgetkeeeLkpgGenipVtneNkeeY 173
            l l+  ++k+l g+ +s+ +d+++vd+ l++ l+ +++     +++++++++f    v ++ l + +  +L+pgG+n+pV +e+++e+
   Q: 611  VLALPGLVWKQLTGETVSWsKDFPAVDSVLVNLLEAMEN-----MDKETFEFRFGeelVYTTPLTDGHMMDLIPGGSNVPVRYEDRKEF 694
           **************************************4.....567778888874455566688999999****************** PP
   S: 174  vklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           ++lv ++rl+e  ++qv+a+++G+ +v+p+ +l+l+t++e+e  +cG++ei+ve+lk+ t+y++ +++++  +q++we+l++f++e+r+
   Q: 695  IRLVQKVRLEE-SRQQVAAMQAGLLKVVPQAVLDLLTWQEVEKKVCGDPEITVEALKRLTRYED-LEQSDVRVQYLWEALSNFTNEDRS 781
           **********9.99************************************************76.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk..dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +fL+FvTg+srlP+       p  +   k  + ++d lP+s+TC ++L LP+Y+s ++++ekL+yA  ++ +++
   Q: 782  RFLRFVTGRSRLPA-------PIYVFPDKqgSDTTDALPQSSTCSSTLYLPNYPSAKVCEEKLRYAAYNCVAID 848
           *************5.......44456666666677*********************************998776 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MALGDNPHLL LGRIRFLNRC IESFRRSEPI PESLCYVPKE VCYKICKDSS SSCSAAAGAA 60
AGGSTVGKTL LAIFESPHQV PHSKKSCKYS IEPKKGTCIR TTGEEYCNSQ GLWVKINKEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCATCCCT GCATCCAGGC TGGGAAACAC AACAGGACAG AGGTGTAATG TCAGTTGTCC 60
TCCCCCTGTT GCTGCCGGGT TGTTGATCCT CTGTTCATCC TCTCCACCAT GGCTCTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	69.56	0.00e+00	1225.00
IUUC-Apl-003715	Anas platyrhynchos	78.81	0.00e+00	1212.00
IUUC-Aca-004377	Anolis carolinensis	72.82	0.00e+00	1283.00
IUUC-Ame-011918	Astyanax mexicanus	78.04	0.00e+00	1373.00
IUUC-Bta-012736	Bos taurus	69.91	0.00e+00	1235.00
IUUC-Cja-019926	Callithrix jacchus	69.67	0.00e+00	1230.00
IUUC-Cfa-020753	Canis familiaris	78.51	0.00e+00	969.00
IUUC-Cpo-021415	Cavia porcellus	69.44	0.00e+00	1230.00
IUUC-Csa-023096	Chlorocebus sabaeus	69.54	0.00e+00	1228.00
IUUC-Dre-028746	Danio rerio	86.57	0.00e+00	1468.00
IUUC-Dno-029293	Dasypus novemcinctus	78.53	0.00e+00	886.00
IUUC-Dor-031113	Dipodomys ordii	78.18	0.00e+00	1013.00
IUUC-Ete-032601	Echinops telfairi	68.09	0.00e+00	1082.00
IUUC-Eca-034198	Equus caballus	67.94	0.00e+00	1223.00
IUUC-Eeu-034708	Erinaceus europaeus	79.46	0.00e+00	754.00
IUUC-Fca-035478	Felis catus	70.48	0.00e+00	1227.00
IUUC-Fal-037366	Ficedula albicollis	72.07	0.00e+00	1259.00
IUUC-Gmo-039020	Gadus morhua	88.69	0.00e+00	1205.00
IUUC-Gga-040332	Gallus gallus	74.68	0.00e+00	1311.00
IUUC-Gac-042336	Gasterosteus aculeatus	89.63	0.00e+00	1580.00
IUUC-Ggo-045382	Gorilla gorilla	69.54	0.00e+00	1228.00
IUUC-Hsa-046562	Homo sapiens	69.54	0.00e+00	1228.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	69.79	0.00e+00	1228.00
IUUC-Lch-049606	Latimeria chalumnae	64.39	0.00e+00	810.00
IUUC-Loc-052448	Lepisosteus oculatus	73.40	0.00e+00	1256.00
IUUC-Laf-054507	Loxodonta africana	69.24	0.00e+00	1241.00
IUUC-Mcc-055690	Macaca mulatta	69.54	0.00e+00	1227.00
IUUC-Meu-055970	Macropus eugenii	68.37	0.00e+00	1195.00
IUUC-Mga-059654	Meleagris gallopavo	79.45	0.00e+00	1202.00
IUUC-Mmr-061069	Microcebus murinus	69.67	0.00e+00	1227.00
IUUC-Mdo-062547	Monodelphis domestica	80.38	0.00e+00	697.00
IUUC-Mmu-063096	Mus musculus	68.51	0.00e+00	1227.00
IUUC-Mpu-065846	Mustela putorius furo	70.02	0.00e+00	1236.00
IUUC-Mlu-067992	Myotis lucifugus	73.60	0.00e+00	1201.00
IUUC-Nle-069565	Nomascus leucogenys	68.36	0.00e+00	1134.00
IUUC-Opr-070853	Ochotona princeps	65.56	0.00e+00	808.00
IUUC-Ont-071628	Oreochromis niloticus	90.76	0.00e+00	1568.00
IUUC-Ocu-074094	Oryctolagus cuniculus	69.67	0.00e+00	1231.00
IUUC-Ola-087384	Oryzias latipes	90.33	0.00e+00	1595.00
IUUC-Oga-088224	Otolemur garnettii	69.44	0.00e+00	1234.00
IUUC-Oar-090043	Ovis aries	67.80	0.00e+00	1171.00
IUUC-Ptr-090852	Pan troglodytes	69.31	0.00e+00	1220.00
IUUC-Pan-092787	Papio anubis	69.54	0.00e+00	1228.00
IUUC-Psi-092986	Pelodiscus sinensis	67.05	0.00e+00	907.00
IUUC-Pma-094416	Petromyzon marinus	39.65	3.00e-174	605.00
IUUC-Pab-098325	Pongo abelii	67.26	0.00e+00	915.00
IUUC-Pca-100885	Procavia capensis	63.31	0.00e+00	935.00
IUUC-Pva-102829	Pteropus vampyrus	58.02	0.00e+00	721.00
IUUC-Rno-104882	Rattus norvegicus	69.79	0.00e+00	1229.00
IUUC-Sha-106811	Sarcophilus harrisii	76.89	2.00e-99	355.00
IUUC-Sar-113020	Sorex araneus	69.05	3.00e-171	595.00
IUUC-Ssc-115436	Sus scrofa	69.12	4.00e-114	404.00
IUUC-Tgu-117042	Taeniopygia guttata	74.88	0.00e+00	1312.00
IUUC-Tru-118419	Takifugu rubripes	86.10	0.00e+00	1453.00
IUUC-Tsy-118829	Tarsius syrichta	69.82	0.00e+00	739.00
IUUC-Tni-120410	Tetraodon nigroviridis	74.62	0.00e+00	1193.00
IUUC-Tbe-128113	Tupaia belangeri	79.32	0.00e+00	642.00
IUUC-Ttr-128167	Tursiops truncatus	66.04	0.00e+00	1143.00
IUUC-Xtr-132910	Xenopus tropicalis	64.38	0.00e+00	1066.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence