iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012955

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02052013

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016091.5	ENSBTAT00000021414.5	ENSBTAP00000021414.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.50e-20	71.2	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.90e-09	35.1	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESH-DDTVNFQDnLHPEVLELLLDFAYSSRIVINE 114
           7************************************9.*******99*****************99886 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L+++  +++l hF+
   Q: 146  PSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFE 177
           89*****************************5 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNI TLFHKASHPD CVLAHLNTLR KHRMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESHDDTVNFQ DNLHPEVLEL LLDFAYSSRI VINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GCGTCCACGA GACCCGCAAG TCGCGGAGCA GCACGGGCTC CATGAACATC 60
ACGCTGTTCC ACAAGGCCTC GCACCCCGAT TGCGTGCTGG CGCACCTCAA CACGCTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

bta:529905

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	95.93	0.00e+00	1197.00
IUUC-Apl-003543	Anas platyrhynchos	88.81	0.00e+00	1084.00
IUUC-Aca-004729	Anolis carolinensis	85.91	0.00e+00	1065.00
IUUC-Ame-011020	Astyanax mexicanus	84.38	0.00e+00	1032.00
IUUC-Cja-018839	Callithrix jacchus	95.08	0.00e+00	1186.00
IUUC-Cfa-020224	Canis familiaris	96.60	0.00e+00	1204.00
IUUC-Cpo-021593	Cavia porcellus	92.53	0.00e+00	1111.00
IUUC-Csa-023276	Chlorocebus sabaeus	95.76	0.00e+00	1192.00
IUUC-Dre-028053	Danio rerio	84.55	0.00e+00	1003.00
IUUC-Dno-029287	Dasypus novemcinctus	94.91	0.00e+00	1177.00
IUUC-Dor-030908	Dipodomys ordii	87.44	0.00e+00	1071.00
IUUC-Fca-035897	Felis catus	96.77	0.00e+00	1201.00
IUUC-Fal-037036	Ficedula albicollis	88.79	0.00e+00	1087.00
IUUC-Gmo-039345	Gadus morhua	84.55	0.00e+00	1004.00
IUUC-Gga-040404	Gallus gallus	88.62	0.00e+00	1089.00
IUUC-Gac-042447	Gasterosteus aculeatus	84.04	0.00e+00	1017.00
IUUC-Ggo-045060	Gorilla gorilla	95.59	0.00e+00	1192.00
IUUC-Hsa-046494	Homo sapiens	95.59	0.00e+00	1191.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	96.26	0.00e+00	1200.00
IUUC-Lch-050211	Latimeria chalumnae	85.20	0.00e+00	1043.00
IUUC-Loc-052578	Lepisosteus oculatus	84.38	0.00e+00	1037.00
IUUC-Laf-053498	Loxodonta africana	95.25	0.00e+00	1138.00
IUUC-Mcc-055033	Macaca mulatta	95.59	0.00e+00	1191.00
IUUC-Meu-056893	Macropus eugenii	91.00	0.00e+00	1139.00
IUUC-Mga-060025	Meleagris gallopavo	88.79	0.00e+00	1088.00
IUUC-Mmr-060658	Microcebus murinus	95.93	0.00e+00	1191.00
IUUC-Mdo-062667	Monodelphis domestica	91.00	0.00e+00	1141.00
IUUC-Mmu-063125	Mus musculus	93.21	0.00e+00	1130.00
IUUC-Mpu-066209	Mustela putorius furo	96.10	0.00e+00	1198.00
IUUC-Mlu-068237	Myotis lucifugus	93.21	0.00e+00	1133.00
IUUC-Nle-069454	Nomascus leucogenys	95.54	0.00e+00	1178.00
IUUC-Ont-072138	Oreochromis niloticus	84.38	0.00e+00	1006.00
IUUC-Oan-073320	Ornithorhynchus anatinus	86.59	0.00e+00	1080.00
IUUC-Ocu-073765	Oryctolagus cuniculus	91.34	0.00e+00	1108.00
IUUC-Oga-088002	Otolemur garnettii	96.26	0.00e+00	1194.00
IUUC-Oar-089481	Ovis aries	99.32	0.00e+00	1224.00
IUUC-Ptr-091200	Pan troglodytes	95.42	0.00e+00	1186.00
IUUC-Psi-093884	Pelodiscus sinensis	88.12	0.00e+00	1078.00
IUUC-Pno-095143	Phaeosphaeria nodorum	26.83	3.00e-14	72.80
IUUC-Pva-102321	Pteropus vampyrus	94.91	0.00e+00	1187.00
IUUC-Rno-104835	Rattus norvegicus	92.70	0.00e+00	1127.00
IUUC-Sha-107528	Sarcophilus harrisii	90.83	0.00e+00	1138.00
IUUC-Ssc-116161	Sus scrofa	97.28	0.00e+00	1205.00
IUUC-Tgu-116569	Taeniopygia guttata	88.62	0.00e+00	1085.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.80	0.00e+00	881.00
IUUC-Ttr-129297	Tursiops truncatus	97.62	0.00e+00	1212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence