iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005025

UUCD1 version

UUC-AnC-00159

Ensembl Protein ID

ENSACAP00000009034.3

UniProt Accession

H9GEX7; H9GEX7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009216.3	ENSACAT00000009227.3	ENSACAP00000009034.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-07	30.8	22	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.pglknssskefrCPlCr 46
           C+iCl+ f+  p+++pCgH f++ Cl   w pg+      +f+CP Cr
   Q: 22   CSICLCLFES-PVTTPCGHNFCLPCLeMTWaPGKA--PGESFSCPQCR 66
           ********99.***************777776666..89999*****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAGLSRAPSL PVLFGLEEEL TCSICLCLFE SPVTTPCGHN FCLPCLEMTW APGKAPGESF 60
SCPQCRTHFH SRPELKKNTV LCRVVEQFER EPAKEEPGPK TVEKKAPQES PVPCDSCLGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCTTCCTG AGTTTCGCTT CTCCGGCTGC TTAAAGAGCC TCCTCCGACT GCTTTCGCTT 60
CATTCTGCAG CCATGGCTGG GCTGAGCAGG GCGCCCTCTC TGCCGGTCCT CTTCGGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

KEGG

acs:100567794

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	47.66	5.00e-172	597.00
IUUC-Apl-004101	Anas platyrhynchos	53.99	0.00e+00	646.00
IUUC-Bta-012735	Bos taurus	48.03	6.00e-173	600.00
IUUC-Cja-019996	Callithrix jacchus	45.36	7.00e-90	323.00
IUUC-Cfa-020466	Canis familiaris	48.12	6.00e-177	613.00
IUUC-Cpo-021737	Cavia porcellus	45.57	4.00e-162	564.00
IUUC-Csa-023217	Chlorocebus sabaeus	49.29	1.00e-174	605.00
IUUC-Dno-030082	Dasypus novemcinctus	48.18	3.00e-176	611.00
IUUC-Dor-030335	Dipodomys ordii	36.08	6.00e-75	275.00
IUUC-Ete-032923	Echinops telfairi	44.44	3.00e-144	505.00
IUUC-Eca-033411	Equus caballus	47.99	1.00e-173	602.00
IUUC-Eeu-034656	Erinaceus europaeus	45.88	2.00e-88	320.00
IUUC-Fca-035371	Felis catus	47.96	1.00e-169	589.00
IUUC-Fal-037008	Ficedula albicollis	48.04	2.00e-175	608.00
IUUC-Gmo-038668	Gadus morhua	35.50	8.00e-111	394.00
IUUC-Gga-040608	Gallus gallus	53.22	0.00e+00	662.00
IUUC-Gac-041409	Gasterosteus aculeatus	38.67	5.00e-63	235.00
IUUC-Ggo-044518	Gorilla gorilla	48.75	2.00e-171	595.00
IUUC-Hsa-045828	Homo sapiens	49.13	1.00e-172	599.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	45.12	1.00e-78	287.00
IUUC-Lch-050478	Latimeria chalumnae	43.83	3.00e-85	309.00
IUUC-Loc-052864	Lepisosteus oculatus	34.14	1.00e-102	366.00
IUUC-Laf-054325	Loxodonta africana	48.09	3.00e-95	341.00
IUUC-Mcc-054920	Macaca mulatta	49.21	1.00e-174	606.00
IUUC-Meu-056367	Macropus eugenii	64.12	1.00e-67	250.00
IUUC-Mga-059975	Meleagris gallopavo	52.41	0.00e+00	638.00
IUUC-Mmr-060748	Microcebus murinus	46.93	2.00e-166	578.00
IUUC-Mdo-062904	Monodelphis domestica	48.01	3.00e-165	575.00
IUUC-Mmu-063891	Mus musculus	46.17	6.00e-167	580.00
IUUC-Mpu-066473	Mustela putorius furo	48.69	5.00e-179	620.00
IUUC-Mlu-068185	Myotis lucifugus	47.31	2.00e-169	588.00
IUUC-Nle-070177	Nomascus leucogenys	49.13	4.00e-172	597.00
IUUC-Opr-070558	Ochotona princeps	42.86	7.00e-83	300.00
IUUC-Ont-071368	Oreochromis niloticus	36.45	9.00e-115	407.00
IUUC-Ocu-074461	Oryctolagus cuniculus	45.98	1.00e-88	320.00
IUUC-Ogu-078203	Oryza glumaepatula	41.03	1.00e-09	57.40
IUUC-Opu-083547	Oryza punctata	41.03	1.00e-09	57.00
IUUC-Ola-087315	Oryzias latipes	25.90	2.00e-56	213.00
IUUC-Oga-088937	Otolemur garnettii	45.12	1.00e-158	552.00
IUUC-Oar-089781	Ovis aries	45.33	1.00e-112	399.00
IUUC-Ptr-090771	Pan troglodytes	49.13	7.00e-172	597.00
IUUC-Pan-092830	Papio anubis	49.53	4.00e-174	604.00
IUUC-Psi-093664	Pelodiscus sinensis	61.80	0.00e+00	768.00
IUUC-Pma-094147	Petromyzon marinus	28.19	1.00e-59	224.00
IUUC-Pab-097588	Pongo abelii	49.29	5.00e-171	593.00
IUUC-Pca-100890	Procavia capensis	48.73	4.00e-169	587.00
IUUC-Pva-102314	Pteropus vampyrus	48.12	1.00e-166	579.00
IUUC-Rno-105234	Rattus norvegicus	47.21	2.00e-86	313.00
IUUC-Sha-106807	Sarcophilus harrisii	47.18	7.00e-166	577.00
IUUC-Sar-113283	Sorex araneus	43.15	2.00e-72	266.00
IUUC-Ssc-115878	Sus scrofa	50.00	2.00e-59	222.00
IUUC-Tgu-117026	Taeniopygia guttata	47.32	2.00e-137	482.00
IUUC-Tru-117794	Takifugu rubripes	37.03	6.00e-106	377.00
IUUC-Tbe-127580	Tupaia belangeri	43.13	4.00e-76	278.00
IUUC-Ttr-128648	Tursiops truncatus	62.31	5.00e-81	295.00
IUUC-Vpa-130254	Vicugna pacos	65.91	9.00e-73	267.00
IUUC-Xtr-132892	Xenopus tropicalis	47.41	2.00e-83	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence