iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050094

Ensembl Protein ID

ENSLACP00000013254.1

UniProt Accession

H3AUD3; H3AUD3_LATCH

Genbank Protein ID

ENSLACP00000013254

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01107260

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011667.1	ENSLACT00000013350.1	ENSLACP00000013254.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.90e-60	199.1	1137	1189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+ +ydy+a n+deL++ kG  + vi  ++ d++W+kg  el+g  GlfP+n+v+ 
   Q: 1137 QVISMYDYSAMNEDELSFSKGTLINVI--NKDDADWWKG--ELNGVTGLFPSNYVKM 1189
           57889**********************..7889******..9*************85 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

SINFFSGING GPNIWAITPE ERVKHNKQFD SLMPLGGCIT GDQARNFFLQ SGLPAPVLAE 60
IWALADINKD GKMDQQEFSI AMKLIKLKLQ GQLLPTVLPP VMKQPPMLSP LTSARFGMGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAATTAACT TTTTTTCTGG GATCAATGTG ATCTCAAGGT TACTGAATGT GGGACAGATT 60
ACTTTTCATT TAGGATTTTC ATCCACATGA TGATTTATGG TAATGACTGT GCAACACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	73.91	0.00e+00	1749.00
IUUC-Apl-004205	Anas platyrhynchos	72.92	0.00e+00	2198.00
IUUC-Aca-004287	Anolis carolinensis	78.31	0.00e+00	1541.00
IUUC-Acl-008379	Aspergillus clavatus	41.77	2.00e-12	68.60
IUUC-Ame-011759	Astyanax mexicanus	66.63	0.00e+00	1285.00
IUUC-Bta-013248	Bos taurus	72.33	0.00e+00	1703.00
IUUC-Cel-018490	Caenorhabditis elegans	32.13	1.00e-57	218.00
IUUC-Cfa-020628	Canis familiaris	74.27	0.00e+00	1761.00
IUUC-Cpo-022427	Cavia porcellus	65.31	0.00e+00	2075.00
IUUC-Csa-023122	Chlorocebus sabaeus	72.70	0.00e+00	1727.00
IUUC-Cho-024969	Choloepus hoffmanni	59.90	0.00e+00	1162.00
IUUC-Cin-025435	Ciona intestinalis	44.68	0.00e+00	950.00
IUUC-Csv-026290	Ciona savignyi	54.93	0.00e+00	734.00
IUUC-Cne-026918	Cryptococcus neoformans	35.43	4.00e-39	157.00
IUUC-Cme-027247	Cyanidioschyzon merolae	26.01	2.00e-10	60.50
IUUC-Dre-027849	Danio rerio	66.45	0.00e+00	1243.00
IUUC-Dno-029419	Dasypus novemcinctus	73.22	0.00e+00	1758.00
IUUC-Dor-030504	Dipodomys ordii	62.73	0.00e+00	1403.00
IUUC-Eca-034196	Equus caballus	72.34	0.00e+00	1675.00
IUUC-Eeu-034972	Erinaceus europaeus	55.53	1.00e-146	514.00
IUUC-Fca-035757	Felis catus	73.39	0.00e+00	1763.00
IUUC-Fal-037531	Ficedula albicollis	81.48	0.00e+00	1607.00
IUUC-Gmo-039555	Gadus morhua	68.69	0.00e+00	1118.00
IUUC-Gga-041012	Gallus gallus	73.04	0.00e+00	1758.00
IUUC-Ggo-045405	Gorilla gorilla	71.96	0.00e+00	2138.00
IUUC-Hsa-046833	Homo sapiens	73.67	0.00e+00	1734.00
IUUC-Loc-052646	Lepisosteus oculatus	75.93	0.00e+00	1496.00
IUUC-Mcc-054709	Macaca mulatta	73.59	0.00e+00	1747.00
IUUC-Meu-056396	Macropus eugenii	72.18	0.00e+00	1386.00
IUUC-Mla-059128	Melampsora laricipopulina	32.05	2.00e-39	159.00
IUUC-Mga-059997	Meleagris gallopavo	74.64	0.00e+00	1840.00
IUUC-Mvi-060268	Microbotryum violaceum	28.31	4.00e-44	174.00
IUUC-Mmr-060891	Microcebus murinus	72.82	0.00e+00	1778.00
IUUC-Mmu-064226	Mus musculus	70.23	0.00e+00	1753.00
IUUC-Mpu-066431	Mustela putorius furo	72.09	0.00e+00	1734.00
IUUC-Mlu-068190	Myotis lucifugus	72.82	0.00e+00	1760.00
IUUC-Nle-070116	Nomascus leucogenys	71.75	0.00e+00	1351.00
IUUC-Opr-070815	Ochotona princeps	64.43	0.00e+00	1441.00
IUUC-Ocu-073753	Oryctolagus cuniculus	56.34	0.00e+00	1759.00
IUUC-Ola-086482	Oryzias latipes	63.06	0.00e+00	1249.00
IUUC-Olu-087698	Ostreococcus lucimarinus	27.18	1.00e-14	75.10
IUUC-Oga-088449	Otolemur garnettii	73.30	0.00e+00	1709.00
IUUC-Oar-090275	Ovis aries	72.33	0.00e+00	1730.00
IUUC-Ptr-091667	Pan troglodytes	73.18	0.00e+00	1727.00
IUUC-Pan-091723	Papio anubis	69.43	0.00e+00	1449.00
IUUC-Psi-093136	Pelodiscus sinensis	74.31	0.00e+00	1751.00
IUUC-Pfo-096733	Poecilia formosa	66.00	0.00e+00	1265.00
IUUC-Pab-098755	Pongo abelii	71.49	0.00e+00	1665.00
IUUC-Pca-101134	Procavia capensis	71.56	0.00e+00	1234.00
IUUC-Pva-102433	Pteropus vampyrus	63.92	0.00e+00	1453.00
IUUC-Pgr-103473	Puccinia graminis	29.85	3.00e-37	151.00
IUUC-Ptt-103973	Puccinia triticina	24.00	1.00e-24	109.00
IUUC-Rno-105691	Rattus norvegicus	73.46	0.00e+00	1780.00
IUUC-Smo-108995	Selaginella moellendorffii	41.82	2.00e-06	47.40
IUUC-Sar-112978	Sorex araneus	69.43	0.00e+00	1095.00
IUUC-Sre-115028	Sporisorium reilianum	34.83	6.00e-32	134.00
IUUC-Ssc-115562	Sus scrofa	67.48	0.00e+00	1550.00
IUUC-Tgu-116758	Taeniopygia guttata	76.39	0.00e+00	1831.00
IUUC-Tru-117714	Takifugu rubripes	66.46	0.00e+00	1243.00
IUUC-Tni-119752	Tetraodon nigroviridis	60.13	0.00e+00	1361.00
IUUC-Tbe-127477	Tupaia belangeri	76.69	0.00e+00	628.00
IUUC-Ttr-129196	Tursiops truncatus	70.72	0.00e+00	1669.00
IUUC-Uma-129456	Ustilago maydis	30.35	3.00e-30	128.00
IUUC-Vpa-130035	Vicugna pacos	69.84	7.00e-157	548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence