iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026058

UUCD1 version

UUC-CiS-00225

Ensembl Protein ID

ENSCSAVP00000005736.1

UniProt Accession

H2YK84; H2YK84_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000003416.1	ENSCSAVT00000005809.1	ENSCSAVP00000005734.1
ENSCSAVG00000003416.1	ENSCSAVT00000005810.1	ENSCSAVP00000005735.1
ENSCSAVG00000003416.1	ENSCSAVT00000005811.1	ENSCSAVP00000005736.1
ENSCSAVG00000003416.1	ENSCSAVT00000005812.1	ENSCSAVP00000005737.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-41	137.8	260	296
UBD/Beta-Prp	2.30e-64	217.4	77	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +H+++++ +++ ++   +++GsdDgtik++Dlr ++ 
   Q: 260  THNSDINTVKWfPTgEAFATGSDDGTIKLYDLRADRE 296
           5***********88799***************99986 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....k 167
             c ++lkgh ++vl++++s ++ ++vs s+d  i vwd  +  + +   s  + +vn  ++ p+g++++ G+lD+++ ++ l    +
   Q: 77   VRCRRILKGHASKVLDMDWSLDRRRIVSSSQDGKILVWDGFNTNKEQ-AISLPTTWVNACAFAPSGSCIACGGLDNKCSVFPLnsssN 163
           5799***********************************98888888.6777778**************************9977543 PP
   S: 168  tgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrs 253
           +    r+    ht+++    f ++  +++++s d+t  lwd+++g+ +++++gh++ v + ++s  + +++++sg++D+   +Wd+r+
   Q: 164  SSVTSRKVVAMHTSYISACMFAHSDYQILTASGDSTCALWDVESGQLLQSFHGHQSDVMDAALSpcETGNLFISGGCDQNACVWDMRT 251
           44444445667*****************************************************999********************* PP
   S: 254  gdllktlq 261
            ++++++q
   Q: 252  AKCIQSFQ 259
           *****997 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MASEKNLTRF DTLENLRKEA EQLRNKLQAD RKNLNDAECK TCHISIHLSC VLQFRLHLLA 60
VFVMGKKAEA SSPTIQVRCR RILKGHASKV LDMDWSLDRR RIVSSSQDGK ILVWDGFNTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTAGATAAT CTTTGAGATA GATAAACCAT ACCCTCTTGC AATATGGCAA GTGAAAAGAA 60
CTTGACAAGA TTTGACACAT TGGAAAATCT ACGCAAAGAA GCTGAACAAT TACGTAACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	57.42	4.00e-123	432.00
IUUC-Apl-003399	Anas platyrhynchos	62.19	6.00e-123	431.00
IUUC-Aca-004861	Anolis carolinensis	57.87	2.00e-130	457.00
IUUC-Ame-011851	Astyanax mexicanus	57.53	3.00e-128	449.00
IUUC-Bta-012438	Bos taurus	57.81	4.00e-128	449.00
IUUC-Cel-018408	Caenorhabditis elegans	56.08	1.00e-116	410.00
IUUC-Cja-019086	Callithrix jacchus	57.71	2.00e-129	454.00
IUUC-Cfa-021255	Canis familiaris	61.37	9.00e-124	434.00
IUUC-Cpo-021398	Cavia porcellus	57.45	4.00e-127	446.00
IUUC-Csa-023776	Chlorocebus sabaeus	57.60	7.00e-129	451.00
IUUC-Cin-025305	Ciona intestinalis	79.85	0.00e+00	637.00
IUUC-Dre-028572	Danio rerio	56.15	6.00e-129	451.00
IUUC-Dor-031013	Dipodomys ordii	63.39	2.00e-102	363.00
IUUC-Dme-031889	Drosophila melanogaster	52.75	2.00e-118	417.00
IUUC-Eca-033977	Equus caballus	56.27	9.00e-125	438.00
IUUC-Eeu-035079	Erinaceus europaeus	58.36	2.00e-128	450.00
IUUC-Fca-035693	Felis catus	61.37	3.00e-123	433.00
IUUC-Fal-037345	Ficedula albicollis	57.87	1.00e-129	454.00
IUUC-Gmo-039222	Gadus morhua	62.31	2.00e-124	436.00
IUUC-Gga-040320	Gallus gallus	57.87	3.00e-129	452.00
IUUC-Gac-042644	Gasterosteus aculeatus	57.81	6.00e-128	448.00
IUUC-Ggo-044489	Gorilla gorilla	56.80	3.00e-123	432.00
IUUC-Hsa-046434	Homo sapiens	57.60	1.00e-128	451.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	58.68	9.00e-112	394.00
IUUC-Loc-052790	Lepisosteus oculatus	61.56	7.00e-124	435.00
IUUC-Laf-054255	Loxodonta africana	57.81	6.00e-127	445.00
IUUC-Mcc-055610	Macaca mulatta	57.71	2.00e-129	453.00
IUUC-Meu-056819	Macropus eugenii	60.94	3.00e-117	412.00
IUUC-Mga-059740	Meleagris gallopavo	61.99	2.00e-123	433.00
IUUC-Mmr-061221	Microcebus murinus	58.08	5.00e-128	449.00
IUUC-Mdo-062619	Monodelphis domestica	57.87	3.00e-129	452.00
IUUC-Mmu-064266	Mus musculus	57.81	7.00e-128	448.00
IUUC-Mpu-065766	Mustela putorius furo	64.55	3.00e-122	429.00
IUUC-Mlu-067221	Myotis lucifugus	61.06	2.00e-121	427.00
IUUC-Nle-069515	Nomascus leucogenys	61.42	7.00e-123	431.00
IUUC-Opr-070195	Ochotona princeps	52.33	4.00e-107	379.00
IUUC-Ont-071535	Oreochromis niloticus	59.29	7.00e-109	385.00
IUUC-Ocu-074666	Oryctolagus cuniculus	64.55	2.00e-122	429.00
IUUC-Ola-086578	Oryzias latipes	65.55	4.00e-124	436.00
IUUC-Oga-089090	Otolemur garnettii	57.77	2.00e-126	443.00
IUUC-Oar-090017	Ovis aries	61.18	6.00e-121	425.00
IUUC-Ptr-091280	Pan troglodytes	59.13	9.00e-123	431.00
IUUC-Pan-092198	Papio anubis	61.95	4.00e-123	432.00
IUUC-Psi-093030	Pelodiscus sinensis	58.86	4.00e-123	432.00
IUUC-Pfo-097182	Poecilia formosa	62.31	4.00e-125	439.00
IUUC-Pab-098157	Pongo abelii	57.60	8.00e-129	452.00
IUUC-Pva-102232	Pteropus vampyrus	64.04	4.00e-110	389.00
IUUC-Rno-105526	Rattus norvegicus	55.01	7.00e-119	418.00
IUUC-Sha-106754	Sarcophilus harrisii	62.07	4.00e-123	432.00
IUUC-Ssc-115390	Sus scrofa	58.20	7.00e-127	445.00
IUUC-Tgu-117377	Taeniopygia guttata	62.38	2.00e-124	437.00
IUUC-Tru-117938	Takifugu rubripes	65.22	6.00e-124	435.00
IUUC-Tsy-119392	Tarsius syrichta	50.14	2.00e-101	360.00
IUUC-Tni-119834	Tetraodon nigroviridis	60.47	1.00e-108	384.00
IUUC-Tbe-127469	Tupaia belangeri	56.44	3.00e-121	426.00
IUUC-Ttr-128252	Tursiops truncatus	57.97	4.00e-128	449.00
IUUC-Vpa-130173	Vicugna pacos	56.44	2.00e-86	310.00
IUUC-Xtr-131803	Xenopus tropicalis	64.88	6.00e-123	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence