iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017374.3	ENSMMUT00000076039.1	ENSMMUP00000052695.1
ENSMMUG00000017374.3	ENSMMUT00000024436.3	ENSMMUP00000022871.3
ENSMMUG00000017374.3	ENSMMUT00000024434.3	ENSMMUP00000022869.3
ENSMMUG00000017374.3	ENSMMUT00000074067.1	ENSMMUP00000047504.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-41	138.5	235	275
UBD/Beta-Prp	5.10e-53	181.3	189	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 235  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 275
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 276
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 365
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiri 248
           h++ v+ +r+sp+++ + sgs D ++r+
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRV 393
           ************************9986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MCDQTFLANV FGSCDKCFKQ RALRPVFKKS QQLSYCSTCA EIMATEALHE NETLASLKSE 60
AESLKGKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT TGCTAATGTA TTTGGCTCAT GTGACAAATG TTTCAAACAA 60
AGAGCTCTGA GACCAGTTTT CAAGAAATCT CAACAACTCA GCTACTGTTC AACATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	92.37	0.00e+00	759.00
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	650.00
IUUC-Aca-004861	Anolis carolinensis	93.38	0.00e+00	775.00
IUUC-Ame-011851	Astyanax mexicanus	92.02	0.00e+00	687.00
IUUC-Bta-012438	Bos taurus	98.86	0.00e+00	724.00
IUUC-Cel-018408	Caenorhabditis elegans	64.72	9.00e-138	483.00
IUUC-Cja-019086	Callithrix jacchus	99.24	0.00e+00	819.00
IUUC-Cfa-021255	Canis familiaris	97.46	0.00e+00	761.00
IUUC-Cpo-021398	Cavia porcellus	96.45	0.00e+00	791.00
IUUC-Csa-023776	Chlorocebus sabaeus	100.00	0.00e+00	731.00
IUUC-Cin-025305	Ciona intestinalis	57.69	5.00e-130	457.00
IUUC-Csv-026058	Ciona savignyi	57.71	7.00e-129	453.00
IUUC-Dre-028432	Danio rerio	84.73	0.00e+00	674.00
IUUC-Dno-029958	Dasypus novemcinctus	86.21	6.00e-146	509.00
IUUC-Dor-031013	Dipodomys ordii	99.21	1.00e-151	529.00
IUUC-Dme-031889	Drosophila melanogaster	68.42	2.00e-147	514.00
IUUC-Ete-033033	Echinops telfairi	80.38	2.00e-97	348.00
IUUC-Eca-033977	Equus caballus	93.89	0.00e+00	764.00
IUUC-Eeu-035079	Erinaceus europaeus	97.44	0.00e+00	790.00
IUUC-Fca-035693	Felis catus	91.90	0.00e+00	754.00
IUUC-Fal-037345	Ficedula albicollis	98.29	0.00e+00	723.00
IUUC-Gmo-039222	Gadus morhua	91.17	0.00e+00	656.00
IUUC-Gga-040320	Gallus gallus	98.29	0.00e+00	723.00
IUUC-Gac-042644	Gasterosteus aculeatus	91.45	0.00e+00	685.00
IUUC-Ggo-044489	Gorilla gorilla	95.44	0.00e+00	773.00
IUUC-Hsa-046434	Homo sapiens	99.49	0.00e+00	815.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.67	6.00e-177	612.00
IUUC-Loc-052790	Lepisosteus oculatus	90.56	0.00e+00	723.00
IUUC-Laf-054255	Loxodonta africana	97.46	0.00e+00	800.00
IUUC-Meu-056819	Macropus eugenii	86.22	0.00e+00	693.00
IUUC-Mga-059740	Meleagris gallopavo	87.97	0.00e+00	715.00
IUUC-Mmr-061221	Microcebus murinus	98.73	0.00e+00	810.00
IUUC-Mdo-062619	Monodelphis domestica	98.01	0.00e+00	719.00
IUUC-Mmu-064266	Mus musculus	98.73	0.00e+00	811.00
IUUC-Mpu-065766	Mustela putorius furo	99.33	2.00e-180	624.00
IUUC-Mlu-067221	Myotis lucifugus	91.14	0.00e+00	744.00
IUUC-Nle-069515	Nomascus leucogenys	99.68	0.00e+00	657.00
IUUC-Opr-070195	Ochotona princeps	90.28	0.00e+00	720.00
IUUC-Ont-071535	Oreochromis niloticus	78.63	2.00e-170	592.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.86	9.00e-109	385.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	1.00e-180	625.00
IUUC-Ola-086578	Oryzias latipes	92.59	0.00e+00	652.00
IUUC-Oga-089090	Otolemur garnettii	97.97	0.00e+00	803.00
IUUC-Oar-090017	Ovis aries	91.84	0.00e+00	735.00
IUUC-Ptr-091280	Pan troglodytes	90.08	0.00e+00	723.00
IUUC-Pan-092198	Papio anubis	99.05	0.00e+00	656.00
IUUC-Psi-093030	Pelodiscus sinensis	85.75	0.00e+00	717.00
IUUC-Pma-094140	Petromyzon marinus	82.16	7.00e-104	369.00
IUUC-Pfo-097182	Poecilia formosa	92.31	0.00e+00	664.00
IUUC-Pab-098157	Pongo abelii	99.72	0.00e+00	731.00
IUUC-Pca-100988	Procavia capensis	77.10	7.00e-169	586.00
IUUC-Pva-102232	Pteropus vampyrus	86.29	2.00e-176	611.00
IUUC-Rno-105526	Rattus norvegicus	95.49	0.00e+00	694.00
IUUC-Sha-106754	Sarcophilus harrisii	96.69	0.00e+00	752.00
IUUC-Ssc-115390	Sus scrofa	98.48	0.00e+00	806.00
IUUC-Tgu-117377	Taeniopygia guttata	88.24	0.00e+00	705.00
IUUC-Tru-117938	Takifugu rubripes	92.31	0.00e+00	651.00
IUUC-Tsy-119392	Tarsius syrichta	84.48	0.00e+00	659.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.77	9.00e-165	572.00
IUUC-Tbe-127469	Tupaia belangeri	96.26	0.00e+00	729.00
IUUC-Ttr-128252	Tursiops truncatus	94.92	0.00e+00	766.00
IUUC-Vpa-130173	Vicugna pacos	80.65	2.00e-157	548.00
IUUC-Xtr-131803	Xenopus tropicalis	91.60	0.00e+00	723.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence