iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093301

Ensembl Protein ID

ENSPSIP00000016592.1

UniProt Accession

K7G8I1; K7G8I1_PELSI

Genbank Protein ID

ENSPSIP00000016592

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01061426

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014749.1	ENSPSIT00000016668.1	ENSPSIP00000016592.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.10e-06	26.3	196	237

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle ++dg  ++v pC H fh++C+  w        ++ +CP Cr
   Q: 196  CAICLEKYMDGeeLRVIPCTHRFHKKCVDPW------LLQHHTCPHCR 237
           ********66555******************......9999******8 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LFQMHPLGLC NSNDEEDLYE YGWVGVVKLE QPELEPKPCL TVLGKAKRAV QRGATAVIFD 60
VSENPDAIDQ LNQGSEDPLK RPVVYVKGAD AVKLMNIVNK QKVARARIQH RPPRQPTEYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATGTGTGT AGGTTTGAGA TGTTGTTATG GTTCTGGATC TCACTTGGGA ATCAGAATCT 60
GCCCCTTCTA GAACACATGA TTTTTGTACA TTATGCTAAC AGTTTCATAT TGGAGTTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	71.59	0.00e+00	940.00
IUUC-Atr-003049	Amborella trichopoda	35.48	2.00e-13	68.20
IUUC-Apl-004188	Anas platyrhynchos	81.58	0.00e+00	1243.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.17	2.00e-15	74.30
IUUC-Afu-009087	Aspergillus fumigatus	52.08	4.00e-13	67.80
IUUC-Ame-011764	Astyanax mexicanus	64.57	0.00e+00	724.00
IUUC-Bta-012478	Bos taurus	52.79	3.00e-152	532.00
IUUC-Bol-016217	Brassica oleracea	56.25	2.00e-14	71.60
IUUC-Bra-017407	Brassica rapa	56.25	2.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	72.31	0.00e+00	1000.00
IUUC-Cfa-020048	Canis familiaris	69.87	0.00e+00	968.00
IUUC-Cpo-021725	Cavia porcellus	67.00	0.00e+00	892.00
IUUC-Csa-023586	Chlorocebus sabaeus	70.67	0.00e+00	949.00
IUUC-Cho-024867	Choloepus hoffmanni	81.86	1.00e-169	589.00
IUUC-Cin-025569	Ciona intestinalis	40.06	3.00e-58	219.00
IUUC-Csv-025869	Ciona savignyi	46.91	1.00e-51	197.00
IUUC-Dre-027553	Danio rerio	63.71	0.00e+00	793.00
IUUC-Dno-029370	Dasypus novemcinctus	70.55	0.00e+00	931.00
IUUC-Dor-030816	Dipodomys ordii	67.30	0.00e+00	872.00
IUUC-Ete-033060	Echinops telfairi	63.47	0.00e+00	683.00
IUUC-Eca-034044	Equus caballus	70.02	0.00e+00	977.00
IUUC-Eeu-034591	Erinaceus europaeus	51.41	2.00e-93	337.00
IUUC-Fca-036000	Felis catus	72.01	0.00e+00	981.00
IUUC-Fal-037147	Ficedula albicollis	80.90	0.00e+00	1243.00
IUUC-Gmo-039099	Gadus morhua	49.83	9.00e-114	403.00
IUUC-Gga-041243	Gallus gallus	79.66	0.00e+00	1019.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.96	1.00e-116	413.00
IUUC-Gma-043731	Glycine max	36.19	4.00e-14	72.00
IUUC-Ggo-044953	Gorilla gorilla	72.10	0.00e+00	972.00
IUUC-Hsa-046484	Homo sapiens	71.77	0.00e+00	977.00
IUUC-Hvu-047249	Hordeum vulgare	44.44	2.00e-12	63.90
IUUC-Itr-048470	Ictidomys tridecemlineatus	71.54	0.00e+00	960.00
IUUC-Lch-050004	Latimeria chalumnae	60.91	0.00e+00	711.00
IUUC-Loc-051830	Lepisosteus oculatus	64.08	0.00e+00	825.00
IUUC-Laf-053975	Loxodonta africana	70.73	0.00e+00	947.00
IUUC-Mcc-055302	Macaca mulatta	69.80	0.00e+00	926.00
IUUC-Meu-056263	Macropus eugenii	71.47	0.00e+00	752.00
IUUC-Mtr-058744	Medicago truncatula	40.66	3.00e-14	71.20
IUUC-Mga-059706	Meleagris gallopavo	82.05	0.00e+00	1269.00
IUUC-Mmr-061372	Microcebus murinus	70.68	0.00e+00	907.00
IUUC-Mdo-062651	Monodelphis domestica	62.21	0.00e+00	816.00
IUUC-Mmu-064339	Mus musculus	70.50	0.00e+00	929.00
IUUC-Mac-064628	Musa acuminata	41.38	1.00e-13	69.70
IUUC-Mpu-066211	Mustela putorius furo	69.75	0.00e+00	918.00
IUUC-Mlu-067058	Myotis lucifugus	71.28	0.00e+00	898.00
IUUC-Nle-069886	Nomascus leucogenys	71.29	0.00e+00	957.00
IUUC-Opr-070218	Ochotona princeps	69.35	0.00e+00	826.00
IUUC-Ont-072483	Oreochromis niloticus	60.38	0.00e+00	803.00
IUUC-Oan-073718	Ornithorhynchus anatinus	69.91	0.00e+00	867.00
IUUC-Ocu-073847	Oryctolagus cuniculus	67.12	0.00e+00	813.00
IUUC-Ogl-077034	Oryza glaberrima	45.71	1.00e-11	63.90
IUUC-Ogu-078680	Oryza glumaepatula	45.71	4.00e-12	65.10
IUUC-Oin-079182	Oryza indica	45.71	6.00e-12	64.70
IUUC-Olo-080549	Oryza longistaminata	54.55	1.00e-12	65.90
IUUC-Ome-081485	Oryza meridionalis	45.71	5.00e-12	65.10
IUUC-Oni-082249	Oryza nivara	45.71	6.00e-12	64.70
IUUC-Oru-084953	Oryza rufipogon	45.71	7.00e-12	64.30
IUUC-Osa-085734	Oryza sativa	45.71	7.00e-12	64.30
IUUC-Ola-087358	Oryzias latipes	64.45	0.00e+00	779.00
IUUC-Oga-088362	Otolemur garnettii	71.25	0.00e+00	967.00
IUUC-Oar-090197	Ovis aries	95.43	2.00e-93	336.00
IUUC-Ptr-091350	Pan troglodytes	71.52	0.00e+00	975.00
IUUC-Pan-091700	Papio anubis	69.79	0.00e+00	924.00
IUUC-Pfo-096917	Poecilia formosa	63.98	0.00e+00	777.00
IUUC-Pab-097932	Pongo abelii	70.45	0.00e+00	995.00
IUUC-Pop-099512	Populus trichocarpa	53.06	6.00e-14	70.10
IUUC-Pca-101054	Procavia capensis	79.66	0.00e+00	791.00
IUUC-Pva-102879	Pteropus vampyrus	70.78	0.00e+00	983.00
IUUC-Sha-106507	Sarcophilus harrisii	53.05	3.00e-161	561.00
IUUC-Sit-110656	Setaria italica	65.12	8.00e-13	66.20
IUUC-Stu-112500	Solanum tuberosum	65.12	2.00e-13	68.20
IUUC-Sar-113182	Sorex araneus	77.66	6.00e-105	375.00
IUUC-Sbi-114132	Sorghum bicolor	50.00	8.00e-11	59.70
IUUC-Ssc-115966	Sus scrofa	67.82	0.00e+00	795.00
IUUC-Tgu-116864	Taeniopygia guttata	75.40	0.00e+00	876.00
IUUC-Tru-118502	Takifugu rubripes	63.68	0.00e+00	762.00
IUUC-Tsy-119210	Tarsius syrichta	73.46	0.00e+00	926.00
IUUC-Tni-120344	Tetraodon nigroviridis	55.73	2.00e-133	468.00
IUUC-Tbe-127735	Tupaia belangeri	67.18	4.00e-96	345.00
IUUC-Ttr-128714	Tursiops truncatus	62.25	0.00e+00	745.00
IUUC-Xtr-132280	Xenopus tropicalis	60.10	0.00e+00	698.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence