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Tag Content
iUUCD ID IUUC-Ggr-040051
Ensembl Protein ID GGTG_03210T0
UniProt Accession J3NPK2; J3NPK2_GAGT3
Genbank Protein ID EJT78107.1
Protein Name Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog
Genbank Nucleotide ID ADBI01000291
Gene Name PAC1; LIS1; GGTG_03210
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
GGTG_03210 GGTG_03210T0 GGTG_03210T0
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-46 153.3 115 150
UBD/Beta-Prp 5.30e-62 209.2 113 399
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
    H++ ++c+af + ++sGsdD+tik+WD+ g l
   Q: 115 HQNTINCIAFhPVySSIASGSDDCTIKIWDWELGEL 150
    99********955568**************876665 PP
   


   UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..ilvtgseDrtikvwdls.tgkcvhtlkghedsvlsl 100
    ++h++ i+c++f+p +s +a+gs+d tik+wd++ g l r+++gh+ +v +v+f + +l+++s+D ik+wd+s ++k ++tl gh++sv ++
   Q: 113 ESHQNTINCIAFHPVYSSIASGSDDCTIKIWDWELGELERTIKGHTRPVLDVDFGGPRGgiLLASCSSDLSIKLWDPSnDYKNIRTLPGHDHSVSAI 209
    578999************************************************866555899************888689**************** PP
   S: 101 sfsp......sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfd 189
    +f+p sg+ lvs+s+d t+++wd+ tg cl+ t +gh+++++ v+ + dg++l s ++D+t+rlWd++ + +l g h+++v++ ++
   Q: 210 RFMPsgatggSGNLLVSASRDTTLKIWDVTTGFCLK-TIRGHTAWIRDVCPSFDGRYLLSTGDDSTLRLWDISVSNPENRLtmVG-HDHYVECCALA 304
    ****999998899***********************.***********************************9999999997455.*********77 PP
   S: 190 sng.....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs.gdllktlqlh 263
    + ++++sgs+d+t+k+wd +g+c++tl+gh+++v+ + f+p +++l s+s+D+s+r+Wdl++ g+++kt+ +
   Q: 305 PPTtypylarlaglkkpppaanaaEFMASGSRDKTIKIWDS-RGTCLKTLIGHDNWVRALVFHPGGKYLFSVSDDKSLRCWDLDQdGKCVKTIGGD 399
    766777778888888889999999****************8.899************************************997626999998765 PP
   

Organism Gaeumannomyces graminis
Functional Description
(View)

Functional Description



     Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Protein Sequence
(Fasta)
MASLLTPRQA DELHKAIVAY LSANNLSNTS NALRAELNLP EEVFDAATQK KYEGLIEKKW 60
TSVVRLQKKI MDLESRNSAL QSELDNATPL SLAKRNSDPT SWLPAPRPRY SLESHQNTIN 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ggr-040051|E3,WD_repeat;UBD,Beta-Prp|Gaeumannomyces graminis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTCTGGTGGG ATCAATTTGG ATTGATTGAC TGTGCCGACG ACCAGCACAT AATTTTTCAA 60
TCGCATTGAA TCAATCGCAT TGCCACGAGC CTTCTCCCAC CCCGACCCAA GAAACAAACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ggr-040051|E3,WD_repeat;UBD,Beta-Prp|Gaeumannomyces graminis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0000132--P:establishment of mitotic spindle orientation
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001589 Ailuropoda melanoleuca 44.85 8.00e-99 352.00
IUUC-Apl-004024 Anas platyrhynchos 45.11 2.00e-102 364.00
IUUC-Aca-004564 Anolis carolinensis 44.63 3.00e-100 357.00
IUUC-Ago-007862 Ashbya gossypii 26.43 1.00e-34 139.00
IUUC-Acl-008360 Aspergillus clavatus 65.39 7.00e-178 615.00
IUUC-Afl-008502 Aspergillus flavus 67.34 5.00e-179 618.00
IUUC-Afu-008848 Aspergillus fumigatus 65.75 0.00e+00 641.00
IUUC-Ani-009173 Aspergillus nidulans 56.49 9.00e-157 545.00
IUUC-Ang-009873 Aspergillus niger 53.48 2.00e-150 524.00
IUUC-Aor-009973 Aspergillus oryzae 63.71 4.00e-171 592.00
IUUC-Ate-010523 Aspergillus terreus 55.65 3.00e-156 543.00
IUUC-Ame-011154 Astyanax mexicanus 45.35 2.00e-102 363.00
IUUC-Bgr-011972 Blumeria graminis 63.30 0.00e+00 641.00
IUUC-Bta-013106 Bos taurus 45.11 1.00e-102 364.00
IUUC-Bci-013615 Botrytis cinerea 65.38 0.00e+00 646.00
IUUC-Cel-018459 Caenorhabditis elegans 40.38 9.00e-87 312.00
IUUC-Cja-018755 Callithrix jacchus 43.91 3.00e-99 353.00
IUUC-Cfa-020749 Canis familiaris 45.11 1.00e-102 364.00
IUUC-Cpo-022371 Cavia porcellus 45.11 1.00e-102 364.00
IUUC-Csa-023524 Chlorocebus sabaeus 44.57 4.00e-84 303.00
IUUC-Cho-024764 Choloepus hoffmanni 40.81 2.00e-80 291.00
IUUC-Cin-025753 Ciona intestinalis 46.56 2.00e-98 350.00
IUUC-Csv-025817 Ciona savignyi 46.65 8.00e-102 362.00
IUUC-Cgl-026529 Colletotrichum gloeosporioides 68.75 0.00e+00 657.00
IUUC-Cne-027087 Cryptococcus neoformans 48.54 8.00e-108 382.00
IUUC-Dre-027554 Danio rerio 45.35 5.00e-102 362.00
IUUC-Dno-029050 Dasypus novemcinctus 45.11 1.00e-102 364.00
IUUC-Dor-030222 Dipodomys ordii 40.91 7.00e-91 325.00
IUUC-Dse-031164 Dothistroma septosporum 62.02 5.00e-174 602.00
IUUC-Dme-031745 Drosophila melanogaster 44.39 5.00e-92 329.00
IUUC-Ete-032508 Echinops telfairi 46.24 2.00e-68 251.00
IUUC-Eca-034288 Equus caballus 44.25 1.00e-97 348.00
IUUC-Eeu-034984 Erinaceus europaeus 40.67 8.00e-90 322.00
IUUC-Fca-036498 Felis catus 45.11 1.00e-102 364.00
IUUC-Fal-036920 Ficedula albicollis 45.11 2.00e-102 364.00
IUUC-Fox-037996 Fusarium oxysporum 68.32 0.00e+00 686.00
IUUC-Fso-038160 Fusarium solani 67.17 0.00e+00 660.00
IUUC-Gmo-038983 Gadus morhua 45.35 4.00e-102 363.00
IUUC-Gga-040623 Gallus gallus 45.11 2.00e-102 364.00
IUUC-Gac-041613 Gasterosteus aculeatus 45.35 5.00e-102 362.00
IUUC-Ggo-045410 Gorilla gorilla 40.69 1.00e-82 298.00
IUUC-Hsa-046358 Homo sapiens 45.11 2.00e-102 364.00
IUUC-Itr-047890 Ictidomys tridecemlineatus 45.11 1.00e-102 364.00
IUUC-Kpa-049351 Komagataella pastoris 29.06 3.00e-43 167.00
IUUC-Lch-049936 Latimeria chalumnae 44.39 4.00e-102 363.00
IUUC-Loc-052476 Lepisosteus oculatus 45.23 3.00e-99 353.00
IUUC-Lma-053170 Leptosphaeria maculans 66.52 6.00e-180 621.00
IUUC-Laf-053713 Loxodonta africana 44.88 1.00e-99 355.00
IUUC-Mcc-054628 Macaca mulatta 45.11 2.00e-102 364.00
IUUC-Meu-055927 Macropus eugenii 38.35 6.00e-49 185.00
IUUC-Mor-056962 Magnaporthe oryzae 87.72 0.00e+00 832.00
IUUC-Mpo-057583 Magnaporthe poae 95.67 0.00e+00 856.00
IUUC-Mla-058819 Melampsora laricipopulina 44.47 1.00e-108 384.00
IUUC-Mga-059945 Meleagris gallopavo 45.11 2.00e-102 363.00
IUUC-Mvi-060403 Microbotryum violaceum 47.55 3.00e-119 420.00
IUUC-Mmr-061289 Microcebus murinus 44.36 4.00e-99 353.00
IUUC-Mdo-061912 Monodelphis domestica 44.63 3.00e-101 360.00
IUUC-Mmu-063253 Mus musculus 45.11 1.00e-102 364.00
IUUC-Mpu-066638 Mustela putorius furo 45.11 1.00e-102 364.00
IUUC-Mlu-067267 Myotis lucifugus 44.29 1.00e-99 355.00
IUUC-Nfi-068571 Neosartorya fischeri 60.42 1.00e-166 577.00
IUUC-Ncr-068895 Neurospora crassa 70.63 0.00e+00 671.00
IUUC-Nle-069087 Nomascus leucogenys 44.07 2.00e-83 300.00
IUUC-Opr-070579 Ochotona princeps 45.11 1.00e-102 364.00
IUUC-Ont-071905 Oreochromis niloticus 45.11 3.00e-102 363.00
IUUC-Oan-073072 Ornithorhynchus anatinus 45.11 1.00e-102 364.00
IUUC-Ocu-074180 Oryctolagus cuniculus 45.11 1.00e-102 364.00
IUUC-Ola-086815 Oryzias latipes 45.58 2.00e-103 367.00
IUUC-Oga-088219 Otolemur garnettii 44.15 1.00e-99 354.00
IUUC-Oar-090394 Ovis aries 45.11 1.00e-102 364.00
IUUC-Ptr-091517 Pan troglodytes 45.11 1.00e-102 364.00
IUUC-Pan-092421 Papio anubis 45.11 2.00e-102 364.00
IUUC-Psi-093370 Pelodiscus sinensis 45.11 3.00e-102 363.00
IUUC-Pma-094319 Petromyzon marinus 43.63 5.00e-83 299.00
IUUC-Pno-094815 Phaeosphaeria nodorum 65.74 0.00e+00 629.00
IUUC-Pfo-097089 Poecilia formosa 46.06 3.00e-103 367.00
IUUC-Pab-098421 Pongo abelii 45.11 1.00e-102 364.00
IUUC-Pca-100120 Procavia capensis 36.49 1.00e-57 215.00
IUUC-Pva-102960 Pteropus vampyrus 44.87 2.00e-101 361.00
IUUC-Pgr-103538 Puccinia graminis 45.20 4.00e-114 403.00
IUUC-Ptt-103990 Puccinia triticina 42.91 1.00e-45 176.00
IUUC-Pte-104261 Pyrenophora teres 66.31 0.00e+00 632.00
IUUC-Pyt-104780 Pyrenophora triticirepentis 66.52 0.00e+00 632.00
IUUC-Rno-105123 Rattus norvegicus 45.11 1.00e-102 364.00
IUUC-Sce-106208 Saccharomyces cerevisiae 28.57 8.00e-37 146.00
IUUC-Sha-107010 Sarcophilus harrisii 44.87 1.00e-101 361.00
IUUC-Sja-107899 Schizosaccharomyces japonicus 34.20 2.00e-66 244.00
IUUC-Ssl-108571 Sclerotinia sclerotiorum 66.89 0.00e+00 626.00
IUUC-Sar-113309 Sorex araneus 44.01 6.00e-96 342.00
IUUC-Sre-115003 Sporisorium reilianum 47.08 2.00e-121 427.00
IUUC-Ssc-116148 Sus scrofa 45.11 1.00e-102 364.00
IUUC-Tgu-117299 Taeniopygia guttata 45.11 2.00e-102 364.00
IUUC-Tru-118179 Takifugu rubripes 45.58 1.00e-102 365.00
IUUC-Tsy-119493 Tarsius syrichta 44.87 2.00e-100 357.00
IUUC-Tni-120355 Tetraodon nigroviridis 45.11 1.00e-100 358.00
IUUC-Tre-121977 Trichoderma reesei 64.44 2.00e-178 616.00
IUUC-Tvi-122661 Trichoderma virens 65.38 2.00e-176 610.00
IUUC-Tme-127031 Tuber melanosporum 64.13 1.00e-174 604.00
IUUC-Tbe-127492 Tupaia belangeri 40.30 4.00e-47 180.00
IUUC-Ttr-128929 Tursiops truncatus 45.11 2.00e-102 364.00
IUUC-Uma-129347 Ustilago maydis 49.46 3.00e-123 433.00
IUUC-Vda-129837 Verticillium dahliae 66.95 4.00e-179 619.00
IUUC-Vpa-130532 Vicugna pacos 37.59 5.00e-79 286.00
IUUC-Xtr-131985 Xenopus tropicalis 44.63 9.00e-102 362.00
IUUC-Xma-133314 Xiphophorus maculatus 45.82 6.00e-103 365.00
IUUC-Yli-134403 Yarrowia lipolytica 40.58 3.00e-94 337.00
Created Date 25-Jun-2017

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