iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089401

Ensembl Protein ID

ENSOARP00000008238.1

UniProt Accession

W5PCS6; W5PCS6_SHEEP

Genbank Protein ID

ENSOARP00000008238

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01001634

Gene Name

USP24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007665.1	ENSOART00000008360.1	ENSOARP00000008238.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-79	268.0	1581	1933

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+N g+tCYmN+v Q+L++ p l e ll+     ++++  ++p+ ++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1581 VGLRNGGATCYMNAVFQQLYMQPGLPESLLS-----VDDD-TDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1661
           6******************************.....5444.468999**************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dq++e+l                          kk+  +++ +++Fqg +++q +c++c ++++ree f+ l+l
   Q: 1662 EQQDAYEFFTSLIDQMDEYL--------------------------KKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNL 1722
           ********************..........................78999************************************ PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            v + +     sl+ +L++f++ e leg+n+yycekck+k++++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp +L++
   Q: 1723 GVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNM 1804
           ******.....9*************************************************************************** PP
   S: 262  spfcts.....peekqke.........................kkkYeLiavvvHsGslssGHYvayvkn....ekgkWllfdDskV 314
           +p+++s     +     +                         +++YeL++v+vHsG+++ GHY++++k+     kgkW++f+D+ +
   Q: 1805 EPYTVSgmarqD-----SssevgengrstdqggggsprkkvalTENYELVGVIVHSGQAHAGHYYSFIKDrrgcGKGKWYKFNDTVI 1886
           ******666550.....34445555555666666666666666***************************55555666********* PP
   S: 315  tevk.eeevleetg.......................staYvlfYkr 337
           +e +  +e le +                        ++aY+lfY+r
   Q: 1887 EEFDlNDETLEYECfggeyrpkvydqtnpytdvrrryWNAYMLFYQR 1933
           ***844666664449******************************98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

KNDENGNCSG ERIEFPTTNL YELESRVLTD HWSIPYKREE SLGKCLLAST YLARLGFSES 60
DENCKRFMDR CMPEAFKKLL TSSAVHKWGT EIHEGIYNML MLLIELVAER MKQDPIPTGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGGCGGC GGCGGGTTCG ACCCCCCGCC CGCGTACCAC GAGGTGGTGG ACGCCGAGGT 60
GAGGAGGGGC GACCCGTGAC CCCCGTGGGA GAGGCCAGCG GGCTGGAGTT CCGTGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	98.45	0.00e+00	4797.00
IUUC-Apl-003203	Anas platyrhynchos	74.68	0.00e+00	3498.00
IUUC-Aca-004396	Anolis carolinensis	91.04	0.00e+00	4429.00
IUUC-Ame-011886	Astyanax mexicanus	84.53	0.00e+00	1768.00
IUUC-Bta-013381	Bos taurus	99.36	0.00e+00	4813.00
IUUC-Cel-018352	Caenorhabditis elegans	30.29	2.00e-62	236.00
IUUC-Cja-018955	Callithrix jacchus	97.93	0.00e+00	4405.00
IUUC-Cfa-020720	Canis familiaris	98.33	0.00e+00	4802.00
IUUC-Cpo-022430	Cavia porcellus	95.48	0.00e+00	3424.00
IUUC-Csa-024180	Chlorocebus sabaeus	98.24	0.00e+00	4623.00
IUUC-Cho-025074	Choloepus hoffmanni	92.44	0.00e+00	1839.00
IUUC-Dre-027696	Danio rerio	80.99	0.00e+00	4001.00
IUUC-Dno-029307	Dasypus novemcinctus	95.60	0.00e+00	4633.00
IUUC-Dor-030889	Dipodomys ordii	94.55	0.00e+00	4590.00
IUUC-Ete-032294	Echinops telfairi	92.41	0.00e+00	2307.00
IUUC-Eca-033823	Equus caballus	92.83	0.00e+00	4509.00
IUUC-Eeu-035178	Erinaceus europaeus	88.99	0.00e+00	2118.00
IUUC-Fca-035444	Felis catus	98.29	0.00e+00	4738.00
IUUC-Fal-037555	Ficedula albicollis	92.76	0.00e+00	4513.00
IUUC-Gmo-038587	Gadus morhua	79.81	0.00e+00	2485.00
IUUC-Gga-041231	Gallus gallus	92.56	0.00e+00	4521.00
IUUC-Gac-041584	Gasterosteus aculeatus	79.75	0.00e+00	2451.00
IUUC-Ggo-044502	Gorilla gorilla	98.29	0.00e+00	4762.00
IUUC-Hsa-045851	Homo sapiens	98.33	0.00e+00	4763.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	97.23	0.00e+00	1566.00
IUUC-Lch-049999	Latimeria chalumnae	79.79	0.00e+00	3816.00
IUUC-Loc-051767	Lepisosteus oculatus	82.89	0.00e+00	3997.00
IUUC-Laf-054139	Loxodonta africana	97.73	0.00e+00	4738.00
IUUC-Mcc-055217	Macaca mulatta	98.17	0.00e+00	4751.00
IUUC-Meu-056659	Macropus eugenii	81.33	0.00e+00	2252.00
IUUC-Mga-059267	Meleagris gallopavo	92.71	0.00e+00	4551.00
IUUC-Mmr-060971	Microcebus murinus	96.97	0.00e+00	4715.00
IUUC-Mdo-061925	Monodelphis domestica	94.17	0.00e+00	4603.00
IUUC-Mmu-064019	Mus musculus	97.29	0.00e+00	4806.00
IUUC-Mpu-066652	Mustela putorius furo	98.33	0.00e+00	4800.00
IUUC-Mlu-067518	Myotis lucifugus	98.09	0.00e+00	4740.00
IUUC-Nle-069763	Nomascus leucogenys	98.01	0.00e+00	4743.00
IUUC-Opr-071031	Ochotona princeps	91.12	0.00e+00	4388.00
IUUC-Ont-072136	Oreochromis niloticus	78.92	0.00e+00	3882.00
IUUC-Oan-072908	Ornithorhynchus anatinus	84.64	0.00e+00	963.00
IUUC-Ocu-073880	Oryctolagus cuniculus	97.21	0.00e+00	4747.00
IUUC-Ola-086544	Oryzias latipes	77.85	0.00e+00	3731.00
IUUC-Oga-088695	Otolemur garnettii	97.93	0.00e+00	4792.00
IUUC-Ptr-091657	Pan troglodytes	98.33	0.00e+00	4759.00
IUUC-Pan-092394	Papio anubis	98.21	0.00e+00	4756.00
IUUC-Psi-093813	Pelodiscus sinensis	93.04	0.00e+00	4536.00
IUUC-Pma-094698	Petromyzon marinus	53.14	3.00e-138	485.00
IUUC-Pfo-096811	Poecilia formosa	79.66	0.00e+00	3869.00
IUUC-Pab-097814	Pongo abelii	98.13	0.00e+00	4751.00
IUUC-Pca-101135	Procavia capensis	92.94	0.00e+00	2224.00
IUUC-Pva-102334	Pteropus vampyrus	94.90	0.00e+00	4533.00
IUUC-Rno-105040	Rattus norvegicus	97.05	0.00e+00	4756.00
IUUC-Sha-106658	Sarcophilus harrisii	94.75	0.00e+00	4652.00
IUUC-Sar-113153	Sorex araneus	86.80	0.00e+00	2744.00
IUUC-Ssc-115641	Sus scrofa	96.89	0.00e+00	4603.00
IUUC-Tgu-117467	Taeniopygia guttata	93.22	0.00e+00	3318.00
IUUC-Tru-118074	Takifugu rubripes	72.48	0.00e+00	3450.00
IUUC-Tsy-119165	Tarsius syrichta	93.71	0.00e+00	4495.00
IUUC-Tni-119923	Tetraodon nigroviridis	68.90	0.00e+00	3214.00
IUUC-Tbe-127910	Tupaia belangeri	88.70	0.00e+00	1778.00
IUUC-Ttr-128218	Tursiops truncatus	97.37	0.00e+00	4754.00
IUUC-Vpa-130090	Vicugna pacos	98.62	0.00e+00	1729.00
IUUC-Xtr-131911	Xenopus tropicalis	85.25	0.00e+00	1715.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence