iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026428

Ensembl Protein ID

ELA25989

UniProt Accession

L2FHW5; L2FHW5_COLGN

Genbank Protein ID

ELA25989.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

KB021087

Gene Name

CGGC5_12971

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_12971	ELA25989	ELA25989

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.80e-57	193.0	23	542

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveah.eesit 98
           YDRQ+rlw + +q++l+sa+vllv  G g++G+E+lKnLvl G+g++t+ D+ tv+ ++l+ +F++++++ gks+A+++ e l elnp v+++ h  +s++
   Q: 23   YDRQLRLWAASGQAALESANVLLVnsGSGTIGVETLKNLVLPGIGKFTIADDTTVTEADLGVNFFLDESSLGKSRAQCCTELLLELNPEVEGDWHpRNSVS 123
           ***********************9445789*****************************************************************445677 PP
   S: 99   eleeeiv..Ffkkf..................dvVvlaldnrear.rkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPf 173
              ++    +++++                  ++++ al  r +  + + +  ++ + pli + + G++ + r  ++g+  + + ++      ++++  P+
   Q: 124  YHRMNHIkeLMCQLqeqetlelgevlgsdspfTIILYALPIRPEHlNALESYSRERKTPLIAIHSAGFYAYFRLRLPGVYPIVDTHPdaiatTDLRLLTPW 224
           777775588888889****************9999999998876625688888888**********************9777776666************* PP
   S: 174  ctlketpn...........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllk 258
            +l  + +            ++ +++ +v++ ++l+ +++ +   ++++++ek e+++ v ++++       eenfeea+++++k  ++ + +s +kq+++
   Q: 225  EELTAFAEnmtkdidgldnHEHGHLPFVVILLHYLKVWRSTHADVPPTNYKEKVEFRKMVANAARVdnaeGGEENFEEAVAAVLKTISQPSLPSaVKQVFE 325
           ******6666666666666999999999********************************9999886665679**************************** PP
   S: 259  sfecdivtkskspfwv....................................................................sfcsnaealq....... 284
           + + +   +s+s+fwv                                                                     fc+na+ ++       
   Q: 326  YQHTN-ELESTSSFWViaaavrsfyekhkclplpgglpdmkaqssvyiklqniykdkarkdaaevlsivrqnpcgesvdpaevdMFCKNAAFIKliipatd 425
           *6665.5*****************************************************************************99999999999988888 PP
   S: 285  .........vpekvekdeevvkasap....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiatt 372
                    + +  + de +++ s+p    l    +al+  +++++ +p         d +++ v++++     + + ++    ++ +e+++   ++++ +
   Q: 426  gdgqlrsvaQ-QEFANDELAKDPSMPmplsLLPIYLALHATSHTSSATP---------DAIMASVQKIL----PDADGNK-RVIEAAHEVSRARGGELHNV 511
           8887777742.33333333333333355666666777788888888877.........55999999888....4555555.56678999************ PP
   S: 373  navvgGlaaqEviKvvsgkfeplknfflfda 403
           +a+ gG++aqE iK++++++ p++n+ +fd+
   Q: 512  SATAGGMVAQETIKIITNQYIPIENTCIFDG 542
           *****************************97 PP

Organism

Colletotrichum gloeosporioides

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTDIIAGQAL PCLSVPSEKE KKYDRQLRLW AASGQAALES ANVLLVNSGS GTIGVETLKN 60
LVLPGIGKFT IADDTTVTEA DLGVNFFLDE SSLGKSRAQC CTELLLELNP EVEGDWHPRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGATA TCATCGCCGG TCAAGCTCTG CCCTGCCTCT CTGTTCCTTC AGAGAAGGAA 60
AAGAAGTATG ATCGCCAGCT CAGATTATGG GCCGCCAGCG GCCAGGCTGC TCTGGAGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.38	9.00e-65	239.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.68	4.00e-76	277.00
IUUC-Atr-002644	Amborella trichopoda	30.24	8.00e-53	199.00
IUUC-Apl-003446	Anas platyrhynchos	32.63	3.00e-68	251.00
IUUC-Aca-004450	Anolis carolinensis	34.15	3.00e-78	284.00
IUUC-Aly-005466	Arabidopsis lyrata	30.50	4.00e-62	230.00
IUUC-Ath-006692	Arabidopsis thaliana	29.91	5.00e-62	230.00
IUUC-Ago-007900	Ashbya gossypii	26.30	6.00e-36	143.00
IUUC-Acl-008333	Aspergillus clavatus	42.24	2.00e-123	434.00
IUUC-Afl-008529	Aspergillus flavus	45.53	7.00e-130	455.00
IUUC-Afu-009071	Aspergillus fumigatus	44.16	2.00e-129	454.00
IUUC-Ani-009443	Aspergillus nidulans	45.86	1.00e-128	451.00
IUUC-Ang-009669	Aspergillus niger	45.08	2.00e-137	480.00
IUUC-Aor-009914	Aspergillus oryzae	45.06	2.00e-129	453.00
IUUC-Ate-010450	Aspergillus terreus	44.63	2.00e-130	457.00
IUUC-Ame-011183	Astyanax mexicanus	32.98	1.00e-74	272.00
IUUC-Bgr-012111	Blumeria graminis	51.30	5.00e-159	552.00
IUUC-Bta-012583	Bos taurus	33.98	8.00e-77	279.00
IUUC-Bci-013892	Botrytis cinerea	59.19	1.00e-170	591.00
IUUC-Bdi-014592	Brachypodium distachyon	31.72	9.00e-65	239.00
IUUC-Bol-016399	Brassica oleracea	30.60	2.00e-62	231.00
IUUC-Bra-017506	Brassica rapa	31.48	1.00e-62	232.00
IUUC-Cel-018456	Caenorhabditis elegans	27.67	4.00e-57	214.00
IUUC-Cja-020007	Callithrix jacchus	33.51	5.00e-75	273.00
IUUC-Cfa-020324	Canis familiaris	34.33	8.00e-78	282.00
IUUC-Cpo-022248	Cavia porcellus	29.49	3.00e-37	147.00
IUUC-Csa-023149	Chlorocebus sabaeus	29.21	7.00e-50	189.00
IUUC-Cho-024537	Choloepus hoffmanni	26.93	2.00e-37	147.00
IUUC-Cin-025763	Ciona intestinalis	32.48	3.00e-73	267.00
IUUC-Csv-026113	Ciona savignyi	32.50	3.00e-75	274.00
IUUC-Cne-026884	Cryptococcus neoformans	29.85	9.00e-50	189.00
IUUC-Cme-027210	Cyanidioschyzon merolae	34.44	3.00e-10	58.50
IUUC-Dre-028140	Danio rerio	34.78	1.00e-81	295.00
IUUC-Dno-030033	Dasypus novemcinctus	36.52	2.00e-69	254.00
IUUC-Dor-030513	Dipodomys ordii	58.42	4.00e-26	110.00
IUUC-Dse-031536	Dothistroma septosporum	41.15	7.00e-117	412.00
IUUC-Dme-031683	Drosophila melanogaster	34.46	6.00e-70	256.00
IUUC-Ete-032420	Echinops telfairi	29.49	1.00e-54	205.00
IUUC-Eca-033992	Equus caballus	31.19	5.00e-48	183.00
IUUC-Eeu-034713	Erinaceus europaeus	58.16	6.00e-27	113.00
IUUC-Fca-036548	Felis catus	34.57	1.00e-76	278.00
IUUC-Fal-037600	Ficedula albicollis	33.39	6.00e-68	249.00
IUUC-Fox-038037	Fusarium oxysporum	59.06	0.00e+00	653.00
IUUC-Fso-038387	Fusarium solani	59.96	0.00e+00	671.00
IUUC-Gmo-038562	Gadus morhua	34.15	2.00e-79	288.00
IUUC-Ggr-040005	Gaeumannomyces graminis	61.48	0.00e+00	681.00
IUUC-Gga-041129	Gallus gallus	33.51	2.00e-74	271.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.60	4.00e-79	286.00
IUUC-Gma-043610	Glycine max	30.82	8.00e-60	223.00
IUUC-Ggo-045611	Gorilla gorilla	33.68	2.00e-75	274.00
IUUC-Hsa-046563	Homo sapiens	33.86	4.00e-77	280.00
IUUC-Hvu-047790	Hordeum vulgare	28.33	1.00e-38	152.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	33.51	4.00e-75	273.00
IUUC-Kpa-049309	Komagataella pastoris	34.07	3.00e-68	251.00
IUUC-Lch-050038	Latimeria chalumnae	32.69	1.00e-71	262.00
IUUC-Lpe-051535	Leersia perrieri	28.28	1.00e-44	172.00
IUUC-Loc-051917	Lepisosteus oculatus	32.19	4.00e-69	253.00
IUUC-Lma-053112	Leptosphaeria maculans	44.35	3.00e-131	460.00
IUUC-Laf-053690	Loxodonta africana	34.33	6.00e-78	283.00
IUUC-Mcc-055117	Macaca mulatta	32.93	2.00e-70	258.00
IUUC-Meu-056761	Macropus eugenii	31.16	5.00e-39	153.00
IUUC-Mor-057230	Magnaporthe oryzae	60.83	0.00e+00	691.00
IUUC-Mpo-057514	Magnaporthe poae	62.88	0.00e+00	671.00
IUUC-Mtr-058551	Medicago truncatula	30.63	1.00e-58	218.00
IUUC-Mla-059183	Melampsora laricipopulina	34.71	9.00e-80	289.00
IUUC-Mga-060144	Meleagris gallopavo	33.39	2.00e-71	261.00
IUUC-Mvi-060221	Microbotryum violaceum	36.28	1.00e-58	219.00
IUUC-Mmr-061325	Microcebus murinus	32.81	8.00e-71	259.00
IUUC-Mdo-062532	Monodelphis domestica	34.03	1.00e-76	278.00
IUUC-Mmu-063956	Mus musculus	33.98	8.00e-77	279.00
IUUC-Mac-064521	Musa acuminata	31.19	4.00e-61	227.00
IUUC-Mpu-066716	Mustela putorius furo	36.38	3.00e-69	254.00
IUUC-Mlu-067459	Myotis lucifugus	33.39	2.00e-75	275.00
IUUC-Nfi-068245	Neosartorya fischeri	44.50	1.00e-130	457.00
IUUC-Ncr-068910	Neurospora crassa	58.73	0.00e+00	661.00
IUUC-Nle-070034	Nomascus leucogenys	31.84	2.00e-66	245.00
IUUC-Opr-070552	Ochotona princeps	34.78	1.00e-36	145.00
IUUC-Ont-071426	Oreochromis niloticus	35.24	2.00e-82	298.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.77	9.00e-45	172.00
IUUC-Ocu-074911	Oryctolagus cuniculus	33.98	1.00e-76	278.00
IUUC-Oba-075437	Oryza barthii	30.02	2.00e-54	204.00
IUUC-Obr-076684	Oryza brachyantha	29.55	1.00e-49	188.00
IUUC-Ogl-077170	Oryza glaberrima	30.02	2.00e-54	204.00
IUUC-Ogu-078844	Oryza glumaepatula	28.89	1.00e-46	179.00
IUUC-Oin-079105	Oryza indica	30.02	1.00e-54	205.00
IUUC-Olo-080943	Oryza longistaminata	28.07	2.00e-39	155.00
IUUC-Oni-082891	Oryza nivara	28.77	1.00e-47	182.00
IUUC-Opu-083457	Oryza punctata	30.20	3.00e-54	204.00
IUUC-Oru-084960	Oryza rufipogon	28.01	1.00e-39	155.00
IUUC-Osa-085358	Oryza sativa	30.02	2.00e-54	204.00
IUUC-Ola-086420	Oryzias latipes	33.25	2.00e-50	190.00
IUUC-Olu-087625	Ostreococcus lucimarinus	27.21	8.00e-43	166.00
IUUC-Oga-088810	Otolemur garnettii	33.45	3.00e-75	274.00
IUUC-Oar-089196	Ovis aries	33.80	4.00e-75	273.00
IUUC-Ptr-090617	Pan troglodytes	33.86	2.00e-76	278.00
IUUC-Pan-092761	Papio anubis	33.86	1.00e-76	278.00
IUUC-Psi-093191	Pelodiscus sinensis	31.91	2.00e-68	251.00
IUUC-Pma-094380	Petromyzon marinus	35.10	2.00e-66	244.00
IUUC-Pno-095084	Phaeosphaeria nodorum	41.22	2.00e-115	409.00
IUUC-Ppa-095798	Physcomitrella patens	29.34	4.00e-60	224.00
IUUC-Pfo-096467	Poecilia formosa	35.28	1.00e-78	285.00
IUUC-Pab-098255	Pongo abelii	35.67	3.00e-68	250.00
IUUC-Pop-099722	Populus trichocarpa	30.76	1.00e-63	235.00
IUUC-Pca-100807	Procavia capensis	35.61	8.00e-24	103.00
IUUC-Ppe-101280	Prunus persica	30.63	8.00e-63	233.00
IUUC-Pva-102333	Pteropus vampyrus	33.63	2.00e-69	254.00
IUUC-Pgr-103401	Puccinia graminis	28.40	7.00e-61	226.00
IUUC-Ptt-103889	Puccinia triticina	28.08	1.00e-55	209.00
IUUC-Pte-104355	Pyrenophora teres	42.81	2.00e-129	454.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	43.66	1.00e-130	458.00
IUUC-Rno-105810	Rattus norvegicus	33.98	3.00e-75	274.00
IUUC-Sce-106397	Saccharomyces cerevisiae	23.84	9.00e-25	106.00
IUUC-Sha-106770	Sarcophilus harrisii	37.71	3.00e-44	170.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	32.14	2.00e-70	258.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.26	5.00e-67	246.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	58.15	0.00e+00	625.00
IUUC-Smo-109296	Selaginella moellendorffii	32.50	3.00e-68	250.00
IUUC-Sit-110157	Setaria italica	29.81	2.00e-64	238.00
IUUC-Sly-111105	Solanum lycopersicum	30.81	6.00e-62	229.00
IUUC-Stu-112469	Solanum tuberosum	31.11	2.00e-62	231.00
IUUC-Sar-113083	Sorex araneus	26.03	8.00e-39	153.00
IUUC-Sbi-113813	Sorghum bicolor	30.09	6.00e-65	239.00
IUUC-Sre-115058	Sporisorium reilianum	35.28	3.00e-56	211.00
IUUC-Tgu-116772	Taeniopygia guttata	32.81	1.00e-68	252.00
IUUC-Tru-118686	Takifugu rubripes	34.90	9.00e-81	292.00
IUUC-Tsy-119111	Tarsius syrichta	34.23	4.00e-34	137.00
IUUC-Tni-120231	Tetraodon nigroviridis	32.00	7.00e-66	243.00
IUUC-Tca-121491	Theobroma cacao	30.59	8.00e-58	216.00
IUUC-Tre-122103	Trichoderma reesei	60.69	0.00e+00	689.00
IUUC-Tvi-122672	Trichoderma virens	62.01	0.00e+00	679.00
IUUC-Tae-125684	Triticum aestivum	32.38	1.00e-64	239.00
IUUC-Tur-126487	Triticum urartu	31.09	6.00e-60	223.00
IUUC-Tme-127097	Tuber melanosporum	38.13	4.00e-93	333.00
IUUC-Ttr-128465	Tursiops truncatus	31.53	1.00e-62	232.00
IUUC-Uma-129645	Ustilago maydis	30.89	1.00e-65	242.00
IUUC-Vda-129989	Verticillium dahliae	56.33	6.00e-165	572.00
IUUC-Vpa-130529	Vicugna pacos	32.40	1.00e-67	248.00
IUUC-Vvi-131059	Vitis vinifera	31.17	2.00e-61	228.00
IUUC-Xtr-132002	Xenopus tropicalis	34.41	6.00e-75	273.00
IUUC-Xma-133930	Xiphophorus maculatus	35.36	9.00e-80	289.00
IUUC-Yli-134505	Yarrowia lipolytica	35.67	1.00e-83	301.00
IUUC-Zma-135619	Zea mays	30.30	1.00e-61	229.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence