iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019731

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01034736

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000014781.2	ENSCJAT00000028785.2	ENSCJAP00000027231.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.70e-62	210.4	441	845

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf  l +s++ a+sp+++l+a +   + fs   qq
   Q: 441  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFGFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 518
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  +++e+++  +++ ++++F+g++ ++i cl c nvssree f+dlsl++p  
   Q: 519  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSLPSSPEEPPAPSSTSVEKMFGGKIMTRICCLCCLNVSSREEAFTDLSLAFPPP 602
           *****************.....667788888888888889999********************************************99 PP
   S: 180  eetkke........................................................................slqdcLesftk 196
           e +  +                                                                        +          
   Q: 603  ERCRRRrlgsvmrpaedlrarelpsaastqgpgkvgpqrqrkhcitgdapptnldiegldsqeaggqssqeekveeegK---------- 681
           98877799***************************************************66666666644442222221.......... PP
   S: 197  eeelegenkyycekckkkqe...................aekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           eee e+e+           e                    ek  + ++l++ L  hL ++     +++r+ki + v++pl  L l+   
   Q: 682  EEETEKEEVR---------EeeestrgeearekekeveeEEKDAEKSELSKGLATHLRCCALVDLRMRRRKILDDVSIPLLrLPLA--- 758
           2222222111.........122233333344444555569999*******************999**************5445554... PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvkn................ekgkWllfdDskVtevkeeevleetg....staYvl 333
                    +++Y+L++vvvHsG s++sGHY++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvl
   Q: 759  GG-------RDQYDLCSVVVHSGvSSESGHYYCYAREgaarpapslgtgdrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVL 840
           33.......678*************************99999999999998888999*******************999********** PP
   S: 334  fYkrr 338
           fY++r
   Q: 841  FYRQR 845
           **985 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MDKILEAVVT SSYPVSVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV GGAEELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGPRA LACVQLGLQL LPEGPAADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC GGTGGTGACG TCGTCGTACC CGGTCAGCGT GAAGCAGGGG 60
CTGGTGAGGC GCGTGCTGGA GGCGGCGCGG CAGCCGCTGG AGCGTGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	87.93	0.00e+00	964.00
IUUC-Apl-004121	Anas platyrhynchos	67.85	0.00e+00	893.00
IUUC-Aca-005070	Anolis carolinensis	65.56	4.00e-164	572.00
IUUC-Bta-012545	Bos taurus	91.78	0.00e+00	1148.00
IUUC-Cfa-020095	Canis familiaris	93.90	0.00e+00	1160.00
IUUC-Cpo-021961	Cavia porcellus	93.05	0.00e+00	1151.00
IUUC-Csa-023167	Chlorocebus sabaeus	89.95	0.00e+00	1417.00
IUUC-Dno-029186	Dasypus novemcinctus	82.96	0.00e+00	835.00
IUUC-Dor-030538	Dipodomys ordii	97.55	0.00e+00	968.00
IUUC-Dme-031871	Drosophila melanogaster	31.17	9.00e-45	175.00
IUUC-Eca-033279	Equus caballus	96.73	0.00e+00	901.00
IUUC-Eeu-035120	Erinaceus europaeus	71.79	0.00e+00	824.00
IUUC-Fca-035969	Felis catus	92.45	0.00e+00	886.00
IUUC-Fal-037625	Ficedula albicollis	67.85	0.00e+00	891.00
IUUC-Ggo-045323	Gorilla gorilla	96.18	0.00e+00	951.00
IUUC-Hsa-046124	Homo sapiens	97.01	0.00e+00	1169.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	94.03	0.00e+00	1137.00
IUUC-Laf-053999	Loxodonta africana	89.02	0.00e+00	1132.00
IUUC-Mcc-055266	Macaca mulatta	95.99	0.00e+00	1154.00
IUUC-Meu-056906	Macropus eugenii	75.00	0.00e+00	984.00
IUUC-Mga-059595	Meleagris gallopavo	71.29	0.00e+00	876.00
IUUC-Mmr-061720	Microcebus murinus	93.33	0.00e+00	718.00
IUUC-Mdo-062167	Monodelphis domestica	75.00	0.00e+00	979.00
IUUC-Mmu-063298	Mus musculus	92.57	0.00e+00	1151.00
IUUC-Mpu-066195	Mustela putorius furo	93.59	0.00e+00	1148.00
IUUC-Mlu-067583	Myotis lucifugus	88.03	0.00e+00	780.00
IUUC-Opr-070454	Ochotona princeps	90.17	6.00e-157	548.00
IUUC-Ocu-074121	Oryctolagus cuniculus	86.38	0.00e+00	942.00
IUUC-Oga-088593	Otolemur garnettii	94.20	0.00e+00	1139.00
IUUC-Oar-090140	Ovis aries	91.48	0.00e+00	1134.00
IUUC-Pan-092168	Papio anubis	90.05	0.00e+00	1418.00
IUUC-Psi-093707	Pelodiscus sinensis	66.76	0.00e+00	888.00
IUUC-Pab-097614	Pongo abelii	96.88	0.00e+00	1174.00
IUUC-Pca-100683	Procavia capensis	88.08	0.00e+00	1108.00
IUUC-Pva-103146	Pteropus vampyrus	80.39	0.00e+00	1018.00
IUUC-Rno-105061	Rattus norvegicus	92.72	0.00e+00	1155.00
IUUC-Sha-106686	Sarcophilus harrisii	73.38	0.00e+00	959.00
IUUC-Tgu-117024	Taeniopygia guttata	72.85	0.00e+00	895.00
IUUC-Tsy-119505	Tarsius syrichta	81.14	4.00e-169	588.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence