iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117740

UUCD1 version

UUC-TaR-00261

Ensembl Protein ID

ENSTRUP00000013106.1

UniProt Accession

H2SL21; H2SL21_TAKRU

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

dcun1d1; LOC101074664

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005458.1	ENSTRUT00000013167.1	ENSTRUP00000013106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	8.00e-89	298.0	60	246
UBD/Alpha-Helix/UBA	4.90e-06	27.7	7	45

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           +kkkle+l++rY+dp++d +igi+g+++fc+dl++dp++++vL++awk++aat+cefs++ef++g+ a+gcdsi+kl+ +l+++e+elk
   Q: 60   DKKKLEQLYNRYRDPHDDnKIGIDGIQQFCDDLTLDPASLSVLLIAWKFRAATQCEFSKQEFMEGMAAQGCDSIDKLKTQLPKMEQELK 148
           79**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           d+ kfkd+Y+f+fnfak++gqk+ldld+aia+w+L+l++r fk+ld+w++fL e++kksi+kDtWnllL+fs++i++d+snYdeegaWP
   Q: 149  DHGKFKDFYQFTFNFAKNPGQKGLDLDMAIAYWNLILSGR-FKFLDLWNTFLLEHHKKSIPKDTWNLLLDFSTMITDDMSNYDEEGAWP 236
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 237  VLIDDFVEFA 246
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++al++L+++++ l++A++ ++
   Q: 7    SQKDKVRQFMIfTQSSEKTALTCLAQNDWKLDVATDKFF 45
           699********9999999******************888 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QNKLKSSQKD KVRQFMIFTQ SSEKTALTCL AQNDWKLDVA TDKFFQNPEL YVPNLKGALD 60
KKKLEQLYNR YRDPHDDNKI GIDGIQQFCD DLTLDPASLS VLLIAWKFRA ATQCEFSKQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACAAGC TGAAGTCCTC ACAGAAGGAT AAAGTTCGTC AGTTCATGAT TTTTACACAA 60
TCCAGTGAGA AGACTGCGTT GACCTGTCTG GCACAGAATG ACTGGAAACT AGATGTTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	44.08	3.00e-60	224.00
IUUC-Aml-001879	Ailuropoda melanoleuca	85.66	6.00e-133	466.00
IUUC-Atr-002662	Amborella trichopoda	37.98	3.00e-25	108.00
IUUC-Apl-003451	Anas platyrhynchos	83.91	3.00e-130	457.00
IUUC-Aca-005269	Anolis carolinensis	85.27	2.00e-131	461.00
IUUC-Aly-006285	Arabidopsis lyrata	40.00	2.00e-46	178.00
IUUC-Ath-007531	Arabidopsis thaliana	46.94	3.00e-61	228.00
IUUC-Acl-008172	Aspergillus clavatus	25.19	8.00e-22	97.10
IUUC-Afl-008569	Aspergillus flavus	30.12	2.00e-29	122.00
IUUC-Ani-009241	Aspergillus nidulans	25.75	1.00e-22	100.00
IUUC-Ang-009664	Aspergillus niger	26.56	3.00e-23	101.00
IUUC-Ame-011763	Astyanax mexicanus	91.41	7.00e-142	495.00
IUUC-Bgr-011991	Blumeria graminis	30.04	2.00e-25	109.00
IUUC-Bta-013561	Bos taurus	84.84	5.00e-125	439.00
IUUC-Bci-013824	Botrytis cinerea	32.68	1.00e-30	126.00
IUUC-Bdi-014138	Brachypodium distachyon	44.49	1.00e-60	226.00
IUUC-Bol-015564	Brassica oleracea	45.71	6.00e-59	220.00
IUUC-Bra-017111	Brassica rapa	45.71	7.00e-59	220.00
IUUC-Cja-019502	Callithrix jacchus	85.66	1.00e-132	465.00
IUUC-Cfa-020523	Canis familiaris	85.25	1.00e-125	441.00
IUUC-Cpo-022196	Cavia porcellus	87.21	1.00e-134	472.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	35.50	1.00e-47	183.00
IUUC-Csa-023551	Chlorocebus sabaeus	86.05	3.00e-133	467.00
IUUC-Cho-024373	Choloepus hoffmanni	84.11	3.00e-126	443.00
IUUC-Cne-026950	Cryptococcus neoformans	32.32	5.00e-30	124.00
IUUC-Dre-028247	Danio rerio	91.41	2.00e-140	491.00
IUUC-Dno-028974	Dasypus novemcinctus	86.05	3.00e-133	467.00
IUUC-Ete-032371	Echinops telfairi	85.66	6.00e-133	466.00
IUUC-Eca-033242	Equus caballus	86.05	3.00e-133	467.00
IUUC-Eeu-035317	Erinaceus europaeus	86.43	1.00e-133	468.00
IUUC-Fca-036061	Felis catus	86.05	2.00e-133	468.00
IUUC-Fal-037372	Ficedula albicollis	83.91	3.00e-130	457.00
IUUC-Gmo-038885	Gadus morhua	89.45	2.00e-139	488.00
IUUC-Gga-040935	Gallus gallus	84.88	5.00e-132	463.00
IUUC-Gac-041937	Gasterosteus aculeatus	92.19	3.00e-142	496.00
IUUC-Gma-043516	Glycine max	44.08	3.00e-59	221.00
IUUC-Ggo-044468	Gorilla gorilla	85.00	5.00e-131	459.00
IUUC-Hsa-046089	Homo sapiens	86.05	3.00e-133	467.00
IUUC-Hvu-047636	Hordeum vulgare	40.65	3.00e-23	101.00
IUUC-Lch-050600	Latimeria chalumnae	86.43	6.00e-134	469.00
IUUC-Lpe-051540	Leersia perrieri	45.12	6.00e-62	230.00
IUUC-Loc-052509	Lepisosteus oculatus	88.72	2.00e-137	481.00
IUUC-Lma-053103	Leptosphaeria maculans	32.30	3.00e-33	135.00
IUUC-Laf-053527	Loxodonta africana	85.27	9.00e-133	465.00
IUUC-Mcc-055699	Macaca mulatta	77.35	3.00e-127	447.00
IUUC-Meu-056626	Macropus eugenii	67.44	1.00e-96	345.00
IUUC-Mor-056909	Magnaporthe oryzae	28.00	3.00e-25	108.00
IUUC-Mpo-057299	Magnaporthe poae	25.82	1.00e-20	93.20
IUUC-Mtr-057964	Medicago truncatula	42.45	2.00e-58	218.00
IUUC-Mla-058990	Melampsora laricipopulina	28.17	1.00e-20	94.00
IUUC-Mmr-060851	Microcebus murinus	86.05	4.00e-133	466.00
IUUC-Mdo-063074	Monodelphis domestica	85.33	2.00e-135	476.00
IUUC-Mmu-063954	Mus musculus	85.27	2.00e-132	464.00
IUUC-Mac-065016	Musa acuminata	47.31	8.00e-44	169.00
IUUC-Mpu-066870	Mustela putorius furo	85.25	1.00e-125	441.00
IUUC-Mlu-067701	Myotis lucifugus	85.66	3.00e-132	464.00
IUUC-Nle-069291	Nomascus leucogenys	86.05	3.00e-133	467.00
IUUC-Opr-070265	Ochotona princeps	62.02	2.00e-80	291.00
IUUC-Ont-071408	Oreochromis niloticus	92.61	5.00e-143	499.00
IUUC-Oan-073031	Ornithorhynchus anatinus	86.43	4.00e-133	467.00
IUUC-Ocu-074648	Oryctolagus cuniculus	86.05	3.00e-133	467.00
IUUC-Oba-074993	Oryza barthii	44.90	1.00e-61	229.00
IUUC-Obr-076341	Oryza brachyantha	45.31	2.00e-62	232.00
IUUC-Ogl-077099	Oryza glaberrima	44.90	1.00e-61	229.00
IUUC-Ogu-078285	Oryza glumaepatula	44.49	2.00e-60	224.00
IUUC-Oin-079441	Oryza indica	44.90	1.00e-61	229.00
IUUC-Olo-081037	Oryza longistaminata	44.90	1.00e-61	229.00
IUUC-Ome-081357	Oryza meridionalis	44.90	1.00e-61	229.00
IUUC-Oni-082632	Oryza nivara	44.90	2.00e-61	228.00
IUUC-Opu-083351	Oryza punctata	45.02	8.00e-58	216.00
IUUC-Oru-084306	Oryza rufipogon	44.90	1.00e-61	229.00
IUUC-Osa-085307	Oryza sativa	44.90	1.00e-61	229.00
IUUC-Ola-086868	Oryzias latipes	88.28	1.00e-135	475.00
IUUC-Oga-089015	Otolemur garnettii	85.66	9.00e-133	465.00
IUUC-Oar-090405	Ovis aries	85.66	9.00e-133	465.00
IUUC-Ptr-090735	Pan troglodytes	86.05	3.00e-133	467.00
IUUC-Pan-092186	Papio anubis	85.71	5.00e-131	459.00
IUUC-Psi-093110	Pelodiscus sinensis	84.84	4.00e-124	436.00
IUUC-Pno-095145	Phaeosphaeria nodorum	31.68	1.00e-23	103.00
IUUC-Ppa-095306	Physcomitrella patens	46.56	2.00e-61	229.00
IUUC-Pfo-096774	Poecilia formosa	86.77	1.00e-135	475.00
IUUC-Pop-098821	Populus trichocarpa	47.12	1.00e-24	104.00
IUUC-Pca-100218	Procavia capensis	83.72	9.00e-132	462.00
IUUC-Pva-102983	Pteropus vampyrus	81.01	3.00e-120	424.00
IUUC-Pgr-103633	Puccinia graminis	29.27	8.00e-28	117.00
IUUC-Ptt-103979	Puccinia triticina	38.81	5.00e-05	42.00
IUUC-Rno-105554	Rattus norvegicus	85.27	3.00e-133	467.00
IUUC-Sha-106888	Sarcophilus harrisii	85.66	4.00e-133	466.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	1.00e-22	99.40
IUUC-Spo-108207	Schizosaccharomyces pombe	33.33	7.00e-26	110.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	34.87	5.00e-34	137.00
IUUC-Sit-110052	Setaria italica	44.53	3.00e-62	231.00
IUUC-Sly-111489	Solanum lycopersicum	45.12	1.00e-61	229.00
IUUC-Stu-112517	Solanum tuberosum	42.28	5.00e-58	217.00
IUUC-Sar-113509	Sorex araneus	65.12	5.00e-91	327.00
IUUC-Sbi-114113	Sorghum bicolor	44.53	2.00e-62	231.00
IUUC-Ssc-115547	Sus scrofa	86.05	3.00e-133	467.00
IUUC-Tgu-117147	Taeniopygia guttata	84.88	4.00e-132	463.00
IUUC-Tsy-119599	Tarsius syrichta	86.43	7.00e-134	469.00
IUUC-Tni-119700	Tetraodon nigroviridis	94.96	2.00e-140	491.00
IUUC-Tca-121033	Theobroma cacao	44.90	5.00e-60	224.00
IUUC-Tre-121986	Trichoderma reesei	29.05	3.00e-21	95.50
IUUC-Tvi-122607	Trichoderma virens	31.15	7.00e-27	114.00
IUUC-Tae-125740	Triticum aestivum	37.76	3.00e-54	205.00
IUUC-Tur-126375	Triticum urartu	34.70	6.00e-51	194.00
IUUC-Tme-126878	Tuber melanosporum	34.51	2.00e-40	159.00
IUUC-Ttr-129086	Tursiops truncatus	76.74	2.00e-114	404.00
IUUC-Vpa-130048	Vicugna pacos	74.42	8.00e-110	389.00
IUUC-Vvi-130834	Vitis vinifera	45.31	8.00e-61	226.00
IUUC-Xtr-131888	Xenopus tropicalis	86.87	3.00e-134	470.00
IUUC-Xma-133834	Xiphophorus maculatus	85.60	3.00e-132	463.00
IUUC-Yli-134595	Yarrowia lipolytica	32.92	5.00e-37	147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence