iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035832

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02052761

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007836.2	ENSFCAT00000007837.2	ENSFCAP00000007255.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.00e-31	107.1	2	95

Active Site

Position(s)	Description	Evidence
35	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 49   leiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspalsvesvllsiqsllaepnpesplneeaaell 126
           ++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+           ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ ++
   Q: 2    ARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMY 90
           689***********************************999999999*9**************************************** PP
   S: 127  kknre 131
           +k++e
   Q: 91   RKWKE 95
           **998 PP

Organism

Felis catus

Protein Sequence
(Fasta)

QARLKFPIDY PYSPPAFRFL TKMWHPNIYE TGDVCISILH PPVDDPQSGE LPSERWNPTQ 60
NVRTILLSVI SLLNEPNTFS PANVDASVMY RKWKESKGKD REYTDIIRKQ VLGTKVDAER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCACGCC TCAAGTTCCC TATCGACTAC CCCTACTCCC CGCCAGCCTT CCGGTTCCTG 60
ACCAAGATGT GGCATCCCAA CATCTACGAG GTGAGCCCAC CGGGCAGGCC CCTCCCGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	99.40	2.00e-96	344.00
IUUC-Ame-011425	Astyanax mexicanus	89.86	7.00e-79	286.00
IUUC-Bta-012516	Bos taurus	98.65	1.00e-84	305.00
IUUC-Cja-018852	Callithrix jacchus	97.93	2.00e-72	265.00
IUUC-Cfa-020203	Canis familiaris	98.80	2.00e-85	308.00
IUUC-Cpo-022139	Cavia porcellus	88.82	5.00e-86	310.00
IUUC-Csa-023371	Chlorocebus sabaeus	97.59	9.00e-87	312.00
IUUC-Dre-028367	Danio rerio	89.86	5.00e-79	286.00
IUUC-Dor-030875	Dipodomys ordii	98.20	2.00e-87	315.00
IUUC-Fal-036936	Ficedula albicollis	98.62	3.00e-83	300.00
IUUC-Gmo-039414	Gadus morhua	90.54	1.00e-79	288.00
IUUC-Gga-040694	Gallus gallus	95.51	3.00e-89	320.00
IUUC-Gac-042485	Gasterosteus aculeatus	89.86	9.00e-80	289.00
IUUC-Ggo-044806	Gorilla gorilla	98.19	9.00e-87	312.00
IUUC-Hsa-046245	Homo sapiens	98.19	9.00e-87	312.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	98.65	7.00e-85	305.00
IUUC-Lch-049845	Latimeria chalumnae	90.54	1.00e-79	288.00
IUUC-Loc-052932	Lepisosteus oculatus	91.89	5.00e-81	293.00
IUUC-Mcc-054665	Macaca mulatta	97.59	1.00e-86	312.00
IUUC-Meu-056360	Macropus eugenii	95.48	1.00e-87	314.00
IUUC-Mga-060075	Meleagris gallopavo	95.51	3.00e-89	321.00
IUUC-Mmr-061165	Microcebus murinus	96.99	1.00e-85	308.00
IUUC-Mdo-061825	Monodelphis domestica	96.39	2.00e-84	305.00
IUUC-Mmu-064168	Mus musculus	99.32	7.00e-85	306.00
IUUC-Mpu-066009	Mustela putorius furo	99.40	3.00e-96	344.00
IUUC-Mlu-067860	Myotis lucifugus	100.00	1.00e-85	308.00
IUUC-Opr-070826	Ochotona princeps	93.82	9.00e-88	315.00
IUUC-Ont-071745	Oreochromis niloticus	91.22	1.00e-80	291.00
IUUC-Oan-073287	Ornithorhynchus anatinus	89.89	1.00e-85	308.00
IUUC-Ocu-074902	Oryctolagus cuniculus	93.92	2.00e-81	295.00
IUUC-Ola-086976	Oryzias latipes	90.34	2.00e-78	285.00
IUUC-Oga-088845	Otolemur garnettii	95.78	2.00e-90	324.00
IUUC-Oar-090180	Ovis aries	99.32	4.00e-85	306.00
IUUC-Ptr-090916	Pan troglodytes	96.99	3.00e-85	307.00
IUUC-Pan-092577	Papio anubis	97.59	9.00e-87	312.00
IUUC-Psi-093039	Pelodiscus sinensis	94.94	3.00e-89	320.00
IUUC-Pfo-096435	Poecilia formosa	90.54	4.00e-80	290.00
IUUC-Pab-098200	Pongo abelii	98.19	2.00e-86	311.00
IUUC-Pca-100169	Procavia capensis	86.43	7.00e-66	242.00
IUUC-Pva-102875	Pteropus vampyrus	99.39	2.00e-85	307.00
IUUC-Rno-106079	Rattus norvegicus	99.32	7.00e-85	306.00
IUUC-Sha-106475	Sarcophilus harrisii	96.39	6.00e-85	306.00
IUUC-Ssc-115699	Sus scrofa	91.53	4.00e-84	303.00
IUUC-Tgu-117466	Taeniopygia guttata	94.94	4.00e-89	320.00
IUUC-Tru-117589	Takifugu rubripes	91.61	1.00e-77	282.00
IUUC-Tni-120864	Tetraodon nigroviridis	87.16	2.00e-76	278.00
IUUC-Ttr-128729	Tursiops truncatus	97.74	9.00e-90	322.00
IUUC-Xtr-132285	Xenopus tropicalis	88.20	2.00e-84	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence