iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004755

UUCD1 version

UUC-AnC-00110

Ensembl Protein ID

ENSACAP00000006523.3

UniProt Accession

H9GBR8; H9GBR8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006665.3	ENSACAT00000006668.3	ENSACAP00000006523.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.50e-07	29.8	14	83
E3 activity/RING/RING	1.50e-08	35.0	18	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl.asggk..tcPvtrqplteedlvPnltlrrliqawce 70
           +++ Cp+ l+l++ Pv++++G+t+   ++ +   +++gk  +cPv+++ ++ e+l  n+ + +l+q++ +
   Q: 14   QDLSCPVCLKLFQSPVTTECGHTFCMDCLSRASkDEDGKatSCPVCQAGTKVEQLCINKQMENLVQSFKQ 83
           6789**************************97653333378*************************9976 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl  f+  p+++ CgH+f+ dCl +   +k++  k+ +CP+C+
   Q: 18   CPVCLKLFQS-PVTTECGHTFCMDCLSRA--SKDEDGKATSCPVCQ 60
           ********99.***************999..9999999*******7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTSSKQRLIQ GMHQDLSCPV CLKLFQSPVT TECGHTFCMD CLSRASKDED GKATSCPVCQ 60
AGTKVEQLCI NKQMENLVQS FKQVPQDHCE EHLDPLSVYC EQDQQVICGV CASLGKHRGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGGTTGCT GTCTCTTTGG TGTCTGCCTG ATTACTGGAT ACGTGCTCTG CGAATACTGC 60
TGGTTCCCCT AAACATTTGC ATTCTCTAGT AAGGATATTT ATGTGGTTTT TTTTCCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

KEGG

acs:100556790

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	53.93	7.00e-130	457.00
IUUC-Apl-004051	Anas platyrhynchos	30.67	9.00e-71	260.00
IUUC-Ame-010964	Astyanax mexicanus	30.21	2.00e-77	283.00
IUUC-Bta-013476	Bos taurus	54.03	4.00e-142	497.00
IUUC-Cja-018969	Callithrix jacchus	60.08	2.00e-151	528.00
IUUC-Cfa-020155	Canis familiaris	62.47	9.00e-173	599.00
IUUC-Cpo-021646	Cavia porcellus	62.23	2.00e-170	591.00
IUUC-Csa-023855	Chlorocebus sabaeus	66.26	9.00e-124	436.00
IUUC-Dno-029142	Dasypus novemcinctus	62.88	2.00e-155	542.00
IUUC-Dor-030394	Dipodomys ordii	56.52	9.00e-72	263.00
IUUC-Ete-032801	Echinops telfairi	62.50	9.00e-49	187.00
IUUC-Eca-034378	Equus caballus	62.05	2.00e-169	588.00
IUUC-Eeu-034526	Erinaceus europaeus	62.66	4.00e-166	577.00
IUUC-Fca-036440	Felis catus	63.11	8.00e-175	606.00
IUUC-Ggo-045086	Gorilla gorilla	63.16	2.00e-131	461.00
IUUC-Hsa-046533	Homo sapiens	64.16	5.00e-169	587.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	62.05	2.00e-171	595.00
IUUC-Lch-050638	Latimeria chalumnae	34.42	3.00e-82	298.00
IUUC-Loc-051971	Lepisosteus oculatus	32.91	2.00e-78	285.00
IUUC-Laf-054479	Loxodonta africana	63.11	1.00e-174	605.00
IUUC-Mcc-055814	Macaca mulatta	62.82	3.00e-161	561.00
IUUC-Meu-056767	Macropus eugenii	64.96	0.00e+00	630.00
IUUC-Mga-059415	Meleagris gallopavo	30.87	8.00e-75	274.00
IUUC-Mmr-061616	Microcebus murinus	63.75	3.00e-176	611.00
IUUC-Mdo-062252	Monodelphis domestica	66.60	0.00e+00	657.00
IUUC-Mmu-063094	Mus musculus	61.62	1.00e-164	572.00
IUUC-Mpu-065885	Mustela putorius furo	52.14	6.00e-131	460.00
IUUC-Mlu-067974	Myotis lucifugus	32.97	1.00e-71	263.00
IUUC-Nle-069476	Nomascus leucogenys	64.24	1.00e-168	585.00
IUUC-Opr-070871	Ochotona princeps	62.90	7.00e-94	337.00
IUUC-Oan-072738	Ornithorhynchus anatinus	69.30	0.00e+00	665.00
IUUC-Ocu-074132	Oryctolagus cuniculus	55.68	6.00e-136	476.00
IUUC-Olu-087666	Ostreococcus lucimarinus	34.21	3.00e-12	66.60
IUUC-Oga-088268	Otolemur garnettii	46.19	4.00e-104	371.00
IUUC-Oar-089555	Ovis aries	49.15	3.00e-110	392.00
IUUC-Ptr-090792	Pan troglodytes	64.16	5.00e-169	587.00
IUUC-Pan-092897	Papio anubis	64.59	1.00e-169	589.00
IUUC-Psi-093742	Pelodiscus sinensis	33.47	2.00e-82	299.00
IUUC-Pab-098716	Pongo abelii	64.16	9.00e-169	586.00
IUUC-Pca-100618	Procavia capensis	56.28	3.00e-146	511.00
IUUC-Pva-102430	Pteropus vampyrus	56.08	4.00e-146	511.00
IUUC-Rno-105665	Rattus norvegicus	61.62	8.00e-172	596.00
IUUC-Sha-106854	Sarcophilus harrisii	55.24	2.00e-154	538.00
IUUC-Sar-113028	Sorex araneus	62.30	8.00e-104	369.00
IUUC-Ssc-116124	Sus scrofa	62.88	6.00e-169	587.00
IUUC-Tbe-127273	Tupaia belangeri	66.53	2.00e-95	342.00
IUUC-Ttr-128947	Tursiops truncatus	32.38	3.00e-71	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence