iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000185271.7	ENST00000637228.1	ENSP00000489731.1
ENSG00000185271.7	ENST00000636854.1	ENSP00000490040.1

Annotation

Cancer Mutation
ICGC	COSMIC	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
TRANSFAC	miRcode
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.70e-16	60.9	237	301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D  l+ gg + ++h++ La  S++F a++l++++es+ + +v ++ ++ + +r l++F Y+g ++
   Q: 237  CDLKLEAGGCQLSVHRAALACGSEFFGAMLLSGMRESQ-GTEVSLRTISTQDLRLLVSFAYSGVVR 301
           89999********************************9.***********************9875 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MSVSDTPHYP PELESVSHPV QRDCLGLLVH AQRTPSWPPS PDEDPRLPSF PLEEPGSRPL 60
VPRNLPFPAL SLEEEEEEEE DEDAAEPEWL RSEEHPSQFF AEAQRLREQR LLLDEEVSVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCGTCT CGGACACCCC ACATTATCCC CCTGAGCTGG AGAGTGTCTC TCATCCCGTC 60
CAGAGGGACT GCCTTGGACT CCTTGTGCAC GCCCAGAGAA CCCCTTCCTG GCCTCCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030609--KLHL33
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003235	Anas platyrhynchos	44.48	2.00e-106	379.00
IUUC-Aca-004274	Anolis carolinensis	42.58	1.00e-119	423.00
IUUC-Ame-011673	Astyanax mexicanus	35.77	7.00e-109	388.00
IUUC-Bta-012653	Bos taurus	87.57	0.00e+00	1102.00
IUUC-Cpo-022302	Cavia porcellus	87.41	0.00e+00	884.00
IUUC-Dre-027396	Danio rerio	34.23	7.00e-110	391.00
IUUC-Dor-030852	Dipodomys ordii	89.05	0.00e+00	939.00
IUUC-Eca-033289	Equus caballus	91.42	0.00e+00	938.00
IUUC-Fca-036241	Felis catus	86.97	0.00e+00	760.00
IUUC-Fal-037076	Ficedula albicollis	43.32	7.00e-108	384.00
IUUC-Gmo-038684	Gadus morhua	33.80	2.00e-84	306.00
IUUC-Gga-040140	Gallus gallus	41.69	5.00e-121	428.00
IUUC-Gac-042620	Gasterosteus aculeatus	35.56	2.00e-94	339.00
IUUC-Lch-049819	Latimeria chalumnae	33.76	3.00e-109	389.00
IUUC-Loc-052436	Lepisosteus oculatus	39.55	2.00e-110	393.00
IUUC-Meu-056736	Macropus eugenii	74.44	0.00e+00	746.00
IUUC-Mga-059274	Meleagris gallopavo	44.46	4.00e-104	372.00
IUUC-Mmr-060708	Microcebus murinus	87.73	0.00e+00	1269.00
IUUC-Mdo-061861	Monodelphis domestica	71.47	0.00e+00	944.00
IUUC-Mpu-066265	Mustela putorius furo	87.19	0.00e+00	819.00
IUUC-Mlu-067761	Myotis lucifugus	81.81	0.00e+00	1145.00
IUUC-Ont-071423	Oreochromis niloticus	36.00	1.00e-102	367.00
IUUC-Ocu-074734	Oryctolagus cuniculus	89.05	0.00e+00	905.00
IUUC-Ola-086918	Oryzias latipes	36.54	2.00e-89	323.00
IUUC-Oar-089239	Ovis aries	89.60	0.00e+00	911.00
IUUC-Pfo-096609	Poecilia formosa	35.59	6.00e-109	388.00
IUUC-Pab-097955	Pongo abelii	98.72	0.00e+00	993.00
IUUC-Pca-100530	Procavia capensis	86.29	4.00e-125	441.00
IUUC-Pva-102693	Pteropus vampyrus	88.32	0.00e+00	824.00
IUUC-Tru-118165	Takifugu rubripes	37.65	7.00e-97	348.00
IUUC-Tsy-119634	Tarsius syrichta	90.51	0.00e+00	956.00
IUUC-Tni-120057	Tetraodon nigroviridis	37.33	2.00e-96	347.00
IUUC-Tbe-127771	Tupaia belangeri	88.70	1.00e-122	433.00
IUUC-Ttr-129275	Tursiops truncatus	89.78	0.00e+00	908.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence