iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019402

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

ACFV01175229

Gene Name

USP51

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000023436.2	ENSCJAT00000044421.2	ENSCJAP00000041929.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-50	171.9	326	515

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L++ip l++++l+ +k+k+  +   +p+ +l++++ +lf+++++++++   p +ll+ ++  ae++ gy+qq
   Q: 326  GLINLGNTCFMNCIVQALTHIPLLKDFFLS-DKHKCIMT---SPSLCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQ 410
           9*****************************.99999875...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl  +ld l+++ k                  s  +e ++++  +++i+++F g l+s+++c++c++vs++ +p +d+sl++pg+
   Q: 411  DAHEFLIAILDVLHRHSKD----------------DSGGQETNNPNCCNCIIDQIFTGGLQSDVTCQTCHSVSTTIDPCWDISLDLPGS 483
           *****************22................12224568999*****************************************98 PP
   S: 180  eetkke....................slqdcL 191
             t  +                    sl+dcL
   Q: 484  CATFDSqnperadstvsredhipgipSLTDCL 515
           87655566777777777777777777777777 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAQVRETSLP SGSGARWSSG GGGGASPEEA VEKAGKMEEE AAGATKASWG QEAEEMKLEP 60
LQERKPAPEE NLTWSSSGGD EKVLPSIPPR CHSSSSPVCP RRTPRPRAWR GSRRRTRPGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCAGG TTCGAGAAAC TTCTTTGCCC TCCGGCTCTG GGGCTCGCTG GAGCTCGGGA 60
GGTGGGGGAG GAGCCTCGCC TGAGGAGGCG GTTGAGAAGG CGGGGAAAAT GGAGGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033383--USP51
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:2001020--P:regulation of response to DNA damage stimulus
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Csa-023824	Chlorocebus sabaeus	96.77	0.00e+00	715.00
IUUC-Hsa-045765	Homo sapiens	97.47	0.00e+00	734.00
IUUC-Mcc-055420	Macaca mulatta	96.15	0.00e+00	747.00
IUUC-Mpu-065679	Mustela putorius furo	81.80	0.00e+00	709.00
IUUC-Nle-069859	Nomascus leucogenys	97.84	0.00e+00	727.00
IUUC-Ocu-074365	Oryctolagus cuniculus	79.93	0.00e+00	722.00
IUUC-Ptr-091479	Pan troglodytes	97.22	0.00e+00	735.00
IUUC-Pan-091707	Papio anubis	96.50	0.00e+00	712.00
IUUC-Pab-097894	Pongo abelii	97.86	0.00e+00	734.00
IUUC-Sar-113426	Sorex araneus	69.45	0.00e+00	636.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence