iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098588

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01309436

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000006746.2	ENSPPYT00000007966.2	ENSPPYP00000007655.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.50e-09	38.2	46	76
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.20e-06	25.0	115	146

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalfl 31
           +Dv+l  g++ f++h++vLaasS++F+a+f+
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFQ 76
           7*****************************5 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L+++  +++l hF+
   Q: 115  PSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFE 146
           89*****************************5 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNV TLFHKASHPD CVLAHLNTLR KHCMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFQPWPA GRSPXXXXFC WFFFFAAIPT LSGRLRRIPG NLLFPSNCLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GTGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGGTC CATGAACGTC 60
ACCCTCTTCC ACAAGGCCTC CCACCCGGAC TGTGTGCTGG CCCACCTCAA CACGCTTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008012	Aspergillus clavatus	35.48	5.00e-04	35.80
IUUC-Cja-018839	Callithrix jacchus	88.29	0.00e+00	1056.00
IUUC-Cpo-021593	Cavia porcellus	81.83	0.00e+00	937.00
IUUC-Csa-023276	Chlorocebus sabaeus	88.96	0.00e+00	1064.00
IUUC-Ggo-045060	Gorilla gorilla	89.13	0.00e+00	1065.00
IUUC-Hsa-046494	Homo sapiens	88.96	0.00e+00	1064.00
IUUC-Laf-053498	Loxodonta africana	85.06	0.00e+00	974.00
IUUC-Mcc-055033	Macaca mulatta	88.79	0.00e+00	1062.00
IUUC-Mmr-060658	Microcebus murinus	86.93	0.00e+00	1045.00
IUUC-Nle-069454	Nomascus leucogenys	89.02	0.00e+00	1052.00
IUUC-Ocu-073765	Oryctolagus cuniculus	80.17	0.00e+00	945.00
IUUC-Oga-088002	Otolemur garnettii	86.93	0.00e+00	1033.00
IUUC-Ptr-091200	Pan troglodytes	88.79	0.00e+00	1060.00
IUUC-Pno-095143	Phaeosphaeria nodorum	27.24	1.00e-15	76.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence