iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040651

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase MIB2

Genbank Nucleotide ID

AADN04000178

Gene Name

MIB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000001473.6	ENSGALT00000002235.4	ENSGALP00000002233.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	68.61	0.00e+00	1405.00	IUUC-Hsa-046523
E3 activity/RING/RING	65.17	0.00e+00	1307.00	IUUC-Mmu-063153
E3 activity/RING/RING	72.50	0.00e+00	1484.00	IUUC-Dre-028844

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gallus gallus

Protein Sequence
(Fasta)

MDLDPYASMQ VGMRVVRGVD WKWGSQDSGE GNVGTVVEIG RTGSPTTPDK TVVVQWDQGN 60
RTNYRTGFQG AYDLLLYDNA QIGVRHPNII CDCCKKHGIR GMRWKCKMCF DYDLCTQCYM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGAGCGG GGTCGAAGGG AGCCTCCGCT GCAGCACCCG CGGGGCCGTC CCGCCTCGGC 60
ACGGCTCTTC GGCCGCTTCC TTGGGGGTAA GAGGGGCACC GGGAAGGAGC TGCCAGAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001370--BIR_rpt
IPR010606--Mib_Herc2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR000433--Znf_ZZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS51416--MIB_HERC2
PS50089--ZF_RING_2
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF12796--Ank_2
PF06701--MIB_HERC2
PF00569--ZZ

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0005769--C:early endosome
GO:0000151--C:ubiquitin ligase complex
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000355	Aegilops tauschii	26.22	1.00e-22	102.00
IUUC-Aml-001839	Ailuropoda melanoleuca	70.04	0.00e+00	1017.00
IUUC-Apl-003333	Anas platyrhynchos	97.05	0.00e+00	1654.00
IUUC-Ath-006662	Arabidopsis thaliana	26.58	8.00e-22	100.00
IUUC-Ame-011227	Astyanax mexicanus	68.68	0.00e+00	1359.00
IUUC-Bta-012993	Bos taurus	66.08	0.00e+00	1259.00
IUUC-Bdi-014301	Brachypodium distachyon	28.18	2.00e-23	105.00
IUUC-Bol-015345	Brassica oleracea	27.76	1.00e-22	102.00
IUUC-Bra-017946	Brassica rapa	26.71	7.00e-23	103.00
IUUC-Cja-019653	Callithrix jacchus	68.40	0.00e+00	1332.00
IUUC-Cfa-020044	Canis familiaris	68.72	0.00e+00	1312.00
IUUC-Cpo-021836	Cavia porcellus	68.48	0.00e+00	1335.00
IUUC-Csa-023940	Chlorocebus sabaeus	68.82	0.00e+00	1362.00
IUUC-Dre-028844	Danio rerio	72.50	0.00e+00	1463.00
IUUC-Dno-030086	Dasypus novemcinctus	63.12	0.00e+00	835.00
IUUC-Dor-030915	Dipodomys ordii	67.17	0.00e+00	649.00
IUUC-Dme-031821	Drosophila melanogaster	46.40	0.00e+00	709.00
IUUC-Ete-033045	Echinops telfairi	68.68	0.00e+00	891.00
IUUC-Eca-034009	Equus caballus	72.19	0.00e+00	1051.00
IUUC-Eeu-035321	Erinaceus europaeus	84.65	1.00e-131	463.00
IUUC-Fal-036757	Ficedula albicollis	94.65	0.00e+00	1912.00
IUUC-Gmo-039304	Gadus morhua	67.79	0.00e+00	1297.00
IUUC-Gac-042061	Gasterosteus aculeatus	69.02	0.00e+00	1368.00
IUUC-Gma-043595	Glycine max	29.17	2.00e-22	101.00
IUUC-Hsa-046523	Homo sapiens	68.72	0.00e+00	1352.00
IUUC-Hvu-047502	Hordeum vulgare	28.62	6.00e-22	99.40
IUUC-Itr-048215	Ictidomys tridecemlineatus	67.62	0.00e+00	1290.00
IUUC-Lch-049427	Latimeria chalumnae	76.32	0.00e+00	1558.00
IUUC-Lpe-051464	Leersia perrieri	27.22	3.00e-16	81.30
IUUC-Loc-052166	Lepisosteus oculatus	74.63	0.00e+00	1507.00
IUUC-Laf-054174	Loxodonta africana	66.05	0.00e+00	900.00
IUUC-Mcc-055748	Macaca mulatta	68.93	0.00e+00	1366.00
IUUC-Meu-056351	Macropus eugenii	68.00	0.00e+00	685.00
IUUC-Mtr-058673	Medicago truncatula	26.96	3.00e-22	101.00
IUUC-Mga-059882	Meleagris gallopavo	81.33	0.00e+00	1543.00
IUUC-Mmr-061388	Microcebus murinus	63.49	0.00e+00	1174.00
IUUC-Mdo-061981	Monodelphis domestica	75.57	0.00e+00	1268.00
IUUC-Mmu-063153	Mus musculus	65.07	0.00e+00	1239.00
IUUC-Mpu-066551	Mustela putorius furo	67.65	0.00e+00	1138.00
IUUC-Nle-069881	Nomascus leucogenys	60.17	0.00e+00	1097.00
IUUC-Opr-070624	Ochotona princeps	54.97	7.00e-175	607.00
IUUC-Ont-072414	Oreochromis niloticus	72.28	0.00e+00	1446.00
IUUC-Oba-075968	Oryza barthii	27.74	5.00e-17	84.00
IUUC-Ogl-077477	Oryza glaberrima	27.74	4.00e-17	84.30
IUUC-Ogu-079004	Oryza glumaepatula	27.74	5.00e-17	84.00
IUUC-Oin-079705	Oryza indica	27.44	5.00e-17	84.00
IUUC-Olo-080410	Oryza longistaminata	27.44	5.00e-17	83.60
IUUC-Ome-081845	Oryza meridionalis	27.13	4.00e-17	84.30
IUUC-Oni-082055	Oryza nivara	27.74	7.00e-17	83.60
IUUC-Oru-085255	Oryza rufipogon	27.13	4.00e-17	84.30
IUUC-Osa-085300	Oryza sativa	26.95	2.00e-14	73.60
IUUC-Ola-086715	Oryzias latipes	67.35	0.00e+00	1384.00
IUUC-Oga-088898	Otolemur garnettii	69.21	0.00e+00	1340.00
IUUC-Oar-089265	Ovis aries	61.48	0.00e+00	825.00
IUUC-Pan-092360	Papio anubis	71.60	0.00e+00	1078.00
IUUC-Psi-093964	Pelodiscus sinensis	86.53	0.00e+00	1708.00
IUUC-Pma-094121	Petromyzon marinus	40.79	4.00e-165	575.00
IUUC-Pfo-096821	Poecilia formosa	72.04	0.00e+00	1447.00
IUUC-Pab-098440	Pongo abelii	57.59	9.00e-173	600.00
IUUC-Pop-098784	Populus trichocarpa	28.72	9.00e-23	103.00
IUUC-Pca-100806	Procavia capensis	60.63	0.00e+00	758.00
IUUC-Ppe-102003	Prunus persica	27.90	2.00e-22	102.00
IUUC-Pva-102667	Pteropus vampyrus	62.29	0.00e+00	810.00
IUUC-Rno-105681	Rattus norvegicus	68.51	0.00e+00	1322.00
IUUC-Sha-106735	Sarcophilus harrisii	73.09	0.00e+00	661.00
IUUC-Sit-109898	Setaria italica	27.30	8.00e-22	99.80
IUUC-Sly-111367	Solanum lycopersicum	27.59	3.00e-21	98.20
IUUC-Sbi-114492	Sorghum bicolor	25.00	2.00e-20	95.50
IUUC-Ssc-116370	Sus scrofa	67.99	0.00e+00	1290.00
IUUC-Tgu-116853	Taeniopygia guttata	93.62	0.00e+00	1883.00
IUUC-Tru-118714	Takifugu rubripes	72.25	0.00e+00	1458.00
IUUC-Tni-119764	Tetraodon nigroviridis	72.25	0.00e+00	1454.00
IUUC-Tca-121711	Theobroma cacao	26.83	2.00e-22	102.00
IUUC-Tae-124169	Triticum aestivum	26.22	7.00e-23	103.00
IUUC-Ttr-128730	Tursiops truncatus	69.09	0.00e+00	701.00
IUUC-Vvi-131705	Vitis vinifera	27.01	3.00e-20	95.10
IUUC-Xtr-132967	Xenopus tropicalis	79.77	0.00e+00	1626.00
IUUC-Xma-133473	Xiphophorus maculatus	71.45	0.00e+00	1264.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence