iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006795

UUCD1 version

UUC-ArT-01316

Ensembl Protein ID

AT4G33270.1

UniProt Accession

Q9SZA4; Q8GY38; Q9SQK2; CDC21_ARATH

Genbank Protein ID

AAF14048.1; CAB38785.1; CAB80044.1; AEE86200.1; BAC42527.1; ABG48494.1

Protein Name

Cell division cycle 20.1, cofactor of APC complex

Genbank Nucleotide ID

AF029262; AL035678; AL161583; CP002687; AK117888; BT026138

Gene Name

CDC20-1; CDC20_2; At4g33270; F17M5.30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G33270	AT4G33270.1	AT4G33270.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.90e-125	419.1	129	435
E3 adaptor/Cullin RING/DCX/DWD	8.60e-30	102.4	264	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl.tghsa 97
           e+ ldap++ ddfylnLldW+s nvla+aL+++vylw+a+tg+ s+l  + eek  vts++w ++g ++avG +++ev+++D ++++++rtl  gh++
   Q: 129  ERTLDAPDIVDDFYLNLLDWGSANVLAIALDHTVYLWDASTGSTSELVTIdEEKGPVTSINWAPDGRHVAVGLNNSEVQLWDSASNRQLRTLkGGHQS 226
           689***********************************************888999************************************778*** PP
   S: 98   rvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse......PlkkfkehkaavkaiawsP 189
           rvg+L+Wn+++l++G+ dg i  +dvr++   ++t+++h+qevCGlkw+ ++++LasGGnDn+v++wd s  +       l++ +eh++avka+aw+P
   Q: 227  RVGSLAWNNHILTTGGMDGLIINNDVRIRSPIVETYRGHTQEVCGLKWSGSGQQLASGGNDNVVHIWDRSVASsnsttqWLHRLEEHTSAVKALAWCP 324
           ********************************************************************87555455666789999************* PP
   S: 190  wqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaag 287
           +q +lLa+GGG  Dr+ikfwnt tga+l+++dtgsqvcsllwsk+++el+s+hGf++n++tlwkyps+ k+ael+gh++Rvl++a spdg ++++aag
   Q: 325  FQANLLATGGGGGDRTIKFWNTHTGACLNSVDTGSQVCSLLWSKNERELLSSHGFTQNQLTLWKYPSMVKMAELTGHTSRVLYMAQSPDGCTVASAAG 422
           ************************************************************************************************** PP
   S: 288  Detlrfwklfdkk 300
           Detlrfw++f   
   Q: 423  DETLRFWNVFGVP 435
           **********765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gHt +v++l++  s+  l+sG++D+++++WD
   Q: 264  GHTQEVCGLKWsgSGQQLASGGNDNVVHIWD 294
           8**********976699************** PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

Protein Sequence
(Fasta)

MDAGMNNTSS HYKTQARCPL QEHFLPRKPS KENLDRFIPN RSAMNFDYAH FALTEGRKGK 60
DQTAAVSSPS KEAYRKQLAE TMNLNHTRIL AFRNKPQAPV ELLPSNHSAS LHQQPKSVKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGGGGCA TTACCGTAAA ACCAAATTTT ACAACGTCTC TCTCCGAAAT ATAGCCGTTA 60
CAGTTTCCAA TTGTAAGATT TAGAGCAAAC CCTAAAAATT GACTCCACTG CTTTATAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0033597--C:mitotic checkpoint complex
GO:0005634--C:nucleus
GO:0019900--F:kinase binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0016567--P:protein ubiquitination

KEGG

ath:AT4G33270

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	70.51	0.00e+00	663.00
IUUC-Aml-001545	Ailuropoda melanoleuca	47.46	2.00e-104	371.00
IUUC-Atr-002628	Amborella trichopoda	69.25	6.00e-175	606.00
IUUC-Apl-003255	Anas platyrhynchos	48.29	3.00e-110	391.00
IUUC-Aca-004920	Anolis carolinensis	47.98	2.00e-104	372.00
IUUC-Aly-006253	Arabidopsis lyrata	98.69	0.00e+00	937.00
IUUC-Bta-012625	Bos taurus	45.98	1.00e-104	372.00
IUUC-Bdi-014063	Brachypodium distachyon	70.40	0.00e+00	668.00
IUUC-Bol-015368	Brassica oleracea	94.85	0.00e+00	887.00
IUUC-Bra-016738	Brassica rapa	94.10	0.00e+00	876.00
IUUC-Cja-019132	Callithrix jacchus	47.93	7.00e-106	377.00
IUUC-Cfa-020780	Canis familiaris	47.45	2.00e-104	372.00
IUUC-Cpo-022223	Cavia porcellus	46.22	5.00e-96	343.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	51.54	3.00e-119	421.00
IUUC-Csa-023666	Chlorocebus sabaeus	47.69	4.00e-105	374.00
IUUC-Cho-024920	Choloepus hoffmanni	64.86	2.00e-42	166.00
IUUC-Csv-026019	Ciona savignyi	46.45	2.00e-102	365.00
IUUC-Cme-027234	Cyanidioschyzon merolae	47.63	1.00e-98	352.00
IUUC-Dre-028026	Danio rerio	43.67	9.00e-106	376.00
IUUC-Dno-028865	Dasypus novemcinctus	46.84	2.00e-102	365.00
IUUC-Dor-030958	Dipodomys ordii	46.59	5.00e-100	357.00
IUUC-Dse-031391	Dothistroma septosporum	47.98	7.00e-95	340.00
IUUC-Dme-031905	Drosophila melanogaster	47.67	3.00e-110	391.00
IUUC-Eeu-035059	Erinaceus europaeus	42.13	4.00e-85	308.00
IUUC-Fal-037558	Ficedula albicollis	47.32	2.00e-107	382.00
IUUC-Gmo-039284	Gadus morhua	45.24	4.00e-103	367.00
IUUC-Gga-040790	Gallus gallus	48.78	5.00e-110	390.00
IUUC-Gac-041431	Gasterosteus aculeatus	43.10	8.00e-98	350.00
IUUC-Gma-043985	Glycine max	79.65	0.00e+00	713.00
IUUC-Ggo-045052	Gorilla gorilla	47.45	6.00e-105	374.00
IUUC-Hsa-046305	Homo sapiens	47.45	6.00e-105	374.00
IUUC-Hvu-047565	Hordeum vulgare	71.12	0.00e+00	655.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	46.21	8.00e-97	347.00
IUUC-Lpe-050954	Leersia perrieri	69.56	1.00e-180	624.00
IUUC-Lma-052998	Leptosphaeria maculans	46.07	9.00e-94	337.00
IUUC-Laf-053742	Loxodonta africana	47.20	4.00e-104	370.00
IUUC-Mcc-054948	Macaca mulatta	47.69	4.00e-105	374.00
IUUC-Mtr-057725	Medicago truncatula	79.33	0.00e+00	727.00
IUUC-Mga-060102	Meleagris gallopavo	48.78	9.00e-110	389.00
IUUC-Mmu-063864	Mus musculus	46.71	6.00e-100	357.00
IUUC-Mac-064861	Musa acuminata	72.75	0.00e+00	672.00
IUUC-Mlu-067277	Myotis lucifugus	46.85	2.00e-104	371.00
IUUC-Nle-070149	Nomascus leucogenys	47.45	3.00e-103	368.00
IUUC-Ont-071660	Oreochromis niloticus	44.65	6.00e-100	357.00
IUUC-Oan-073677	Ornithorhynchus anatinus	49.06	2.00e-98	352.00
IUUC-Ocu-073797	Oryctolagus cuniculus	47.69	3.00e-105	375.00
IUUC-Oba-075514	Oryza barthii	70.61	0.00e+00	629.00
IUUC-Obr-076018	Oryza brachyantha	68.29	0.00e+00	654.00
IUUC-Ogl-077254	Oryza glaberrima	70.61	0.00e+00	630.00
IUUC-Ogu-078562	Oryza glumaepatula	70.40	0.00e+00	629.00
IUUC-Oin-080094	Oryza indica	70.61	0.00e+00	630.00
IUUC-Olo-080449	Oryza longistaminata	70.82	0.00e+00	638.00
IUUC-Ome-081186	Oryza meridionalis	69.43	0.00e+00	650.00
IUUC-Oni-082243	Oryza nivara	70.61	0.00e+00	630.00
IUUC-Opu-084007	Oryza punctata	70.19	0.00e+00	627.00
IUUC-Oru-084357	Oryza rufipogon	70.40	0.00e+00	628.00
IUUC-Osa-086094	Oryza sativa	70.40	0.00e+00	629.00
IUUC-Ola-086907	Oryzias latipes	47.26	4.00e-99	354.00
IUUC-Olu-087647	Ostreococcus lucimarinus	54.69	1.00e-131	462.00
IUUC-Oga-088184	Otolemur garnettii	46.84	2.00e-101	362.00
IUUC-Ptr-090935	Pan troglodytes	46.96	3.00e-103	368.00
IUUC-Pan-091845	Papio anubis	47.69	4.00e-105	374.00
IUUC-Psi-093188	Pelodiscus sinensis	46.83	5.00e-107	380.00
IUUC-Pma-094187	Petromyzon marinus	45.52	4.00e-97	348.00
IUUC-Pno-094809	Phaeosphaeria nodorum	47.44	1.00e-94	340.00
IUUC-Ppa-095687	Physcomitrella patens	63.45	4.00e-152	530.00
IUUC-Pfo-097429	Poecilia formosa	40.90	9.00e-89	320.00
IUUC-Pab-098603	Pongo abelii	47.69	4.00e-105	374.00
IUUC-Pop-098890	Populus trichocarpa	83.37	0.00e+00	766.00
IUUC-Pca-101062	Procavia capensis	46.08	2.00e-105	375.00
IUUC-Ppe-101865	Prunus persica	80.09	0.00e+00	723.00
IUUC-Pva-102925	Pteropus vampyrus	46.70	3.00e-105	375.00
IUUC-Pte-104142	Pyrenophora teres	45.97	3.00e-94	338.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	45.97	3.00e-94	338.00
IUUC-Rno-106005	Rattus norvegicus	44.10	4.00e-100	357.00
IUUC-Sha-107472	Sarcophilus harrisii	46.03	3.00e-101	361.00
IUUC-Smo-108922	Selaginella moellendorffii	60.81	6.00e-157	546.00
IUUC-Sit-110032	Setaria italica	69.62	0.00e+00	645.00
IUUC-Sly-111202	Solanum lycopersicum	82.03	0.00e+00	744.00
IUUC-Stu-112676	Solanum tuberosum	78.34	0.00e+00	737.00
IUUC-Sar-113092	Sorex araneus	45.28	1.00e-95	343.00
IUUC-Sbi-114558	Sorghum bicolor	70.68	0.00e+00	653.00
IUUC-Ssc-115710	Sus scrofa	45.98	1.00e-104	373.00
IUUC-Tgu-117100	Taeniopygia guttata	47.32	2.00e-107	382.00
IUUC-Tru-118184	Takifugu rubripes	42.89	7.00e-90	323.00
IUUC-Tca-120949	Theobroma cacao	82.28	0.00e+00	787.00
IUUC-Tae-123918	Triticum aestivum	69.75	0.00e+00	660.00
IUUC-Tur-126193	Triticum urartu	71.62	0.00e+00	662.00
IUUC-Tbe-127384	Tupaia belangeri	51.06	2.00e-84	305.00
IUUC-Ttr-128511	Tursiops truncatus	47.20	2.00e-104	372.00
IUUC-Vvi-131245	Vitis vinifera	80.13	0.00e+00	693.00
IUUC-Xtr-131993	Xenopus tropicalis	49.52	1.00e-111	396.00
IUUC-Xma-133332	Xiphophorus maculatus	45.99	3.00e-105	374.00
IUUC-Zma-135456	Zea mays	69.68	0.00e+00	655.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence