iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010430

Ensembl Protein ID

CADATEAP00010367

UniProt Accession

Q0CS30; Q0CS30_ASPTN

Genbank Protein ID

EAU36778.1

Protein Name

NEDD8-conjugating enzyme Ubc12

Genbank Nucleotide ID

CH476597

Gene Name

ATEG_03504

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00010367	CADATEAT00010367	CADATEAP00010367

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.10e-34	118.3	35	176

Active Site

Position(s)	Description	Evidence
113	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           R++++l+el+  ++ ++  ++ + +d+ ++ ++i+ p++ +Y+gg F++++++++++P +PPkvk+++ki+hPn++ +G+vCl+il+  e+W+
   Q: 35   RVQRDLQELALGSTMKM--SFPNPDDILNFVLTIE-PDEGMYKGGSFHFNFSVNQNFPHDPPKVKCTQKIYHPNIDLEGNVCLNILR--EDWK 122
           89999999977666555..5555557*********.**************************************************9..**** PP
   S: 94   palsvesvl..lsiqsll.......aepnpesplneeaaellkknreeykkkvr 138
           p+l+++ v+  ++++s+l        epn ++pln+eaa+ l++nr ++kk+vr
   Q: 123  PVLNLNAVIvgMQVCSFLpliiflfLEPNASDPLNKEAADDLRTNRDAFKKNVR 176
           ********966677787777777779**************************98 PP

Organism

Aspergillus terreus

Protein Sequence
(Fasta)

MLTALLDQKQ KQQQAENAEG AAGKKKKKVT AAQLRVQRDL QELALGSTMK MSFPNPDDIL 60
NFVLTIEPDE GMYKGGSFHF NFSVNQNFPH DPPKVKCTQK IYHPNIDLEG NVCLNILRED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTAACGG CGCTCCTGGA CCAGAAACAA AAGCAGCAGC AGGCTGAGAA TGCGGAGGGC 60
GCCGCGGGGA AGAAAAAGAA GAAGGTTACC GCCGCGCAGT TGCGCGTGCA GCGAGGTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000196	Aegilops tauschii	55.13	1.00e-46	176.00
IUUC-Aml-002007	Ailuropoda melanoleuca	58.97	2.00e-51	192.00
IUUC-Atr-003170	Amborella trichopoda	53.70	1.00e-46	177.00
IUUC-Aca-005037	Anolis carolinensis	58.64	3.00e-54	202.00
IUUC-Aly-005638	Arabidopsis lyrata	53.09	5.00e-46	175.00
IUUC-Ath-006846	Arabidopsis thaliana	54.94	3.00e-47	179.00
IUUC-Ago-007910	Ashbya gossypii	44.03	7.00e-37	144.00
IUUC-Acl-008364	Aspergillus clavatus	84.47	1.00e-79	286.00
IUUC-Afl-008463	Aspergillus flavus	86.34	3.00e-80	288.00
IUUC-Afu-008803	Aspergillus fumigatus	86.34	1.00e-80	290.00
IUUC-Ani-009422	Aspergillus nidulans	85.09	5.00e-78	281.00
IUUC-Ang-009728	Aspergillus niger	85.62	9.00e-73	263.00
IUUC-Aor-009962	Aspergillus oryzae	86.34	3.00e-80	288.00
IUUC-Ame-011382	Astyanax mexicanus	59.88	1.00e-55	206.00
IUUC-Bgr-012306	Blumeria graminis	68.52	8.00e-66	240.00
IUUC-Bta-012818	Bos taurus	59.26	9.00e-55	204.00
IUUC-Bci-013626	Botrytis cinerea	65.43	1.00e-63	233.00
IUUC-Bdi-014079	Brachypodium distachyon	55.56	8.00e-49	184.00
IUUC-Bol-016135	Brassica oleracea	53.09	3.00e-46	175.00
IUUC-Bra-017368	Brassica rapa	53.70	1.00e-46	177.00
IUUC-Cja-019213	Callithrix jacchus	57.49	1.00e-52	197.00
IUUC-Cfa-020242	Canis familiaris	58.54	3.00e-53	199.00
IUUC-Cpo-022405	Cavia porcellus	55.56	2.00e-49	186.00
IUUC-Cre-022865	Chlamydomonas reinhardtii	50.33	1.00e-41	160.00
IUUC-Csa-023269	Chlorocebus sabaeus	59.26	9.00e-55	204.00
IUUC-Cin-025333	Ciona intestinalis	58.02	1.00e-52	196.00
IUUC-Csv-025898	Ciona savignyi	58.06	9.00e-50	187.00
IUUC-Cgl-026477	Colletotrichum gloeosporioides	72.84	5.00e-70	254.00
IUUC-Cne-027097	Cryptococcus neoformans	62.73	3.00e-60	221.00
IUUC-Cme-027287	Cyanidioschyzon merolae	47.44	6.00e-22	95.10
IUUC-Dre-028514	Danio rerio	59.88	2.00e-55	206.00
IUUC-Dno-029678	Dasypus novemcinctus	58.97	2.00e-51	192.00
IUUC-Dor-030940	Dipodomys ordii	38.57	5.00e-22	95.50
IUUC-Dse-031265	Dothistroma septosporum	74.07	4.00e-71	258.00
IUUC-Dme-032076	Drosophila melanogaster	58.86	4.00e-53	198.00
IUUC-Ete-032350	Echinops telfairi	41.94	6.00e-23	97.40
IUUC-Eca-034075	Equus caballus	58.64	8.00e-54	201.00
IUUC-Fca-035654	Felis catus	58.97	2.00e-51	192.00
IUUC-Fal-037283	Ficedula albicollis	62.65	3.00e-27	110.00
IUUC-Fox-037877	Fusarium oxysporum	72.05	5.00e-69	251.00
IUUC-Fso-038428	Fusarium solani	72.84	7.00e-71	257.00
IUUC-Gmo-039402	Gadus morhua	59.88	1.00e-55	206.00
IUUC-Ggr-039731	Gaeumannomyces graminis	74.07	7.00e-71	257.00
IUUC-Gga-041122	Gallus gallus	54.72	1.00e-47	181.00
IUUC-Gac-041480	Gasterosteus aculeatus	37.32	9.00e-23	97.80
IUUC-Gma-043805	Glycine max	53.70	5.00e-46	175.00
IUUC-Ggo-044436	Gorilla gorilla	59.26	9.00e-55	204.00
IUUC-Hsa-046026	Homo sapiens	59.26	9.00e-55	204.00
IUUC-Hvu-047056	Hordeum vulgare	55.00	1.00e-47	180.00
IUUC-Itr-047889	Ictidomys tridecemlineatus	59.26	9.00e-55	204.00
IUUC-Kpa-049315	Komagataella pastoris	53.12	1.00e-45	174.00
IUUC-Lch-050360	Latimeria chalumnae	49.69	1.00e-39	154.00
IUUC-Lpe-050743	Leersia perrieri	53.37	6.00e-47	178.00
IUUC-Lma-053001	Leptosphaeria maculans	75.93	3.00e-72	262.00
IUUC-Laf-053463	Loxodonta africana	58.33	7.00e-51	190.00
IUUC-Mcc-054966	Macaca mulatta	70.27	6.00e-30	120.00
IUUC-Meu-056085	Macropus eugenii	57.42	1.00e-49	186.00
IUUC-Mor-057250	Magnaporthe oryzae	73.29	5.00e-69	251.00
IUUC-Mpo-057481	Magnaporthe poae	73.91	9.00e-70	254.00
IUUC-Mtr-058251	Medicago truncatula	53.70	1.00e-45	174.00
IUUC-Mla-059119	Melampsora laricipopulina	70.37	2.00e-65	239.00
IUUC-Mga-059881	Meleagris gallopavo	63.73	1.00e-36	142.00
IUUC-Mvi-060449	Microbotryum violaceum	63.75	9.00e-57	210.00
IUUC-Mmr-061511	Microcebus murinus	70.27	4.00e-30	120.00
IUUC-Mdo-061993	Monodelphis domestica	37.50	4.00e-22	96.70
IUUC-Mmu-063962	Mus musculus	59.26	9.00e-55	204.00
IUUC-Mac-064995	Musa acuminata	56.17	6.00e-50	187.00
IUUC-Mpu-066423	Mustela putorius furo	38.19	1.00e-22	97.10
IUUC-Mlu-066955	Myotis lucifugus	58.12	8.00e-52	193.00
IUUC-Nfi-068300	Neosartorya fischeri	86.34	1.00e-80	290.00
IUUC-Ncr-068944	Neurospora crassa	72.22	9.00e-70	254.00
IUUC-Nle-069051	Nomascus leucogenys	58.97	2.00e-51	192.00
IUUC-Opr-070635	Ochotona princeps	58.71	7.00e-51	190.00
IUUC-Ont-072348	Oreochromis niloticus	59.88	2.00e-55	206.00
IUUC-Ocu-074905	Oryctolagus cuniculus	59.26	9.00e-55	204.00
IUUC-Oba-075825	Oryza barthii	54.38	3.00e-47	179.00
IUUC-Obr-076431	Oryza brachyantha	54.94	2.00e-48	183.00
IUUC-Ogl-077404	Oryza glaberrima	54.32	4.00e-48	182.00
IUUC-Ogu-078073	Oryza glumaepatula	54.38	3.00e-47	179.00
IUUC-Oin-080060	Oryza indica	54.32	5.00e-48	183.00
IUUC-Olo-080602	Oryza longistaminata	54.38	3.00e-47	181.00
IUUC-Ome-081870	Oryza meridionalis	54.32	4.00e-48	182.00
IUUC-Oni-082192	Oryza nivara	54.38	1.00e-47	180.00
IUUC-Opu-083942	Oryza punctata	55.63	2.00e-46	176.00
IUUC-Oru-084750	Oryza rufipogon	54.38	1.00e-47	180.00
IUUC-Osa-085857	Oryza sativa	54.32	3.00e-48	182.00
IUUC-Olu-087854	Ostreococcus lucimarinus	53.99	1.00e-49	187.00
IUUC-Oga-088580	Otolemur garnettii	59.26	9.00e-55	204.00
IUUC-Oar-089623	Ovis aries	56.41	4.00e-47	178.00
IUUC-Ptr-091020	Pan troglodytes	58.71	7.00e-51	190.00
IUUC-Pan-092119	Papio anubis	58.97	2.00e-51	192.00
IUUC-Psi-093494	Pelodiscus sinensis	58.33	9.00e-51	190.00
IUUC-Pno-094972	Phaeosphaeria nodorum	74.69	4.00e-72	261.00
IUUC-Ppa-095751	Physcomitrella patens	57.41	1.00e-52	197.00
IUUC-Pfo-097205	Poecilia formosa	59.76	2.00e-54	202.00
IUUC-Pab-098434	Pongo abelii	59.26	9.00e-55	204.00
IUUC-Pop-099789	Populus trichocarpa	52.47	7.00e-47	177.00
IUUC-Pca-100300	Procavia capensis	58.06	3.00e-50	188.00
IUUC-Ppe-101143	Prunus persica	54.94	2.00e-47	179.00
IUUC-Pva-102143	Pteropus vampyrus	59.26	9.00e-55	204.00
IUUC-Pgr-103675	Puccinia graminis	69.38	7.00e-64	234.00
IUUC-Ptt-103997	Puccinia triticina	68.75	4.00e-64	234.00
IUUC-Pte-104042	Pyrenophora teres	75.31	2.00e-72	262.00
IUUC-Pyt-104616	Pyrenophora triticirepentis	75.64	2.00e-69	252.00
IUUC-Rno-105107	Rattus norvegicus	59.26	9.00e-55	204.00
IUUC-Sce-106385	Saccharomyces cerevisiae	42.86	6.00e-36	141.00
IUUC-Sha-106899	Sarcophilus harrisii	57.69	7.00e-50	187.00
IUUC-Sja-107789	Schizosaccharomyces japonicus	54.66	2.00e-49	186.00
IUUC-Spo-108143	Schizosaccharomyces pombe	55.90	5.00e-52	194.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	65.43	2.00e-63	233.00
IUUC-Smo-108673	Selaginella moellendorffii	58.64	7.00e-52	194.00
IUUC-Sit-109702	Setaria italica	55.62	1.00e-47	180.00
IUUC-Sly-111045	Solanum lycopersicum	54.94	1.00e-47	180.00
IUUC-Stu-112655	Solanum tuberosum	54.94	2.00e-48	182.00
IUUC-Sar-113632	Sorex araneus	59.26	1.00e-54	204.00
IUUC-Sbi-114357	Sorghum bicolor	56.25	2.00e-48	182.00
IUUC-Sre-114912	Sporisorium reilianum	68.32	9.00e-66	240.00
IUUC-Ssc-115597	Sus scrofa	37.50	3.00e-22	95.90
IUUC-Tgu-117397	Taeniopygia guttata	36.81	5.00e-22	95.50
IUUC-Tru-118496	Takifugu rubripes	37.32	7.00e-23	98.20
IUUC-Tsy-119639	Tarsius syrichta	65.56	2.00e-33	132.00
IUUC-Tni-119674	Tetraodon nigroviridis	60.00	2.00e-42	163.00
IUUC-Tca-121359	Theobroma cacao	54.94	2.00e-47	179.00
IUUC-Tre-122115	Trichoderma reesei	72.84	2.00e-70	256.00
IUUC-Tvi-122656	Trichoderma virens	71.60	9.00e-70	253.00
IUUC-Tae-124489	Triticum aestivum	55.00	1.00e-47	180.00
IUUC-Tur-126125	Triticum urartu	54.66	1.00e-47	181.00
IUUC-Tme-126950	Tuber melanosporum	72.84	3.00e-68	248.00
IUUC-Tbe-127874	Tupaia belangeri	55.86	1.00e-30	124.00
IUUC-Ttr-128213	Tursiops truncatus	60.53	8.00e-51	190.00
IUUC-Uma-129329	Ustilago maydis	67.50	5.00e-65	238.00
IUUC-Vda-129754	Verticillium dahliae	73.46	1.00e-70	257.00
IUUC-Vvi-131337	Vitis vinifera	53.70	2.00e-47	179.00
IUUC-Xtr-132742	Xenopus tropicalis	58.64	4.00e-54	202.00
IUUC-Xma-133558	Xiphophorus maculatus	60.49	7.00e-56	207.00
IUUC-Yli-134467	Yarrowia lipolytica	65.84	4.00e-62	228.00
IUUC-Zma-135527	Zea mays	57.50	4.00e-49	185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence