iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000001555.2	ENSCJAT00000002986.2	ENSCJAP00000002828.2
ENSCJAG00000001555.2	ENSCJAT00000003000.2	ENSCJAP00000002840.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.10e-14	54.4	654	719

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 654  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 719
           79*********9977765156789*********************************..*******85 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAGPQMGGSA EDHPPRKRHA AAKQKKKKII YTKCFEFESA TQLPRHLRDA PAAYNSALQN 60
KSVSGMCLES QTLNQLYQGD FVHAVEGKDF NYEYVQREAL RVPLIFREKD GLGIKMPDPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGTC CGCAAATGGG GGGATCTGCA GAGGATCACC CCCCACGAAA AAGACATGCA 60
GCAGCAAAAC AAAAAAAGAA AAAAATTATA TATACAAAAT GCTTTGAATT TGAGTCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	92.70	0.00e+00	2159.00
IUUC-Apl-003787	Anas platyrhynchos	80.90	0.00e+00	1859.00
IUUC-Aca-004247	Anolis carolinensis	75.04	0.00e+00	1698.00
IUUC-Bta-013531	Bos taurus	92.53	0.00e+00	2179.00
IUUC-Cfa-020857	Canis familiaris	92.77	0.00e+00	2180.00
IUUC-Cpo-021967	Cavia porcellus	89.10	0.00e+00	1989.00
IUUC-Csa-023210	Chlorocebus sabaeus	94.72	0.00e+00	2145.00
IUUC-Dre-028272	Danio rerio	61.21	0.00e+00	1420.00
IUUC-Dno-030034	Dasypus novemcinctus	91.11	0.00e+00	2098.00
IUUC-Dor-030736	Dipodomys ordii	85.95	0.00e+00	993.00
IUUC-Eca-034255	Equus caballus	93.95	0.00e+00	2154.00
IUUC-Eeu-035038	Erinaceus europaeus	96.80	0.00e+00	1176.00
IUUC-Fca-035786	Felis catus	92.87	0.00e+00	2204.00
IUUC-Fal-037589	Ficedula albicollis	79.97	0.00e+00	1911.00
IUUC-Gga-041103	Gallus gallus	80.66	0.00e+00	1021.00
IUUC-Gac-041304	Gasterosteus aculeatus	59.16	0.00e+00	1412.00
IUUC-Ggo-044522	Gorilla gorilla	97.28	0.00e+00	1738.00
IUUC-Hsa-045877	Homo sapiens	93.23	0.00e+00	2226.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	95.60	0.00e+00	1306.00
IUUC-Lch-049950	Latimeria chalumnae	75.12	0.00e+00	1793.00
IUUC-Loc-051972	Lepisosteus oculatus	66.50	0.00e+00	983.00
IUUC-Laf-053623	Loxodonta africana	92.12	0.00e+00	2048.00
IUUC-Mcc-054943	Macaca mulatta	93.38	0.00e+00	2224.00
IUUC-Meu-056259	Macropus eugenii	81.83	0.00e+00	1945.00
IUUC-Mga-059671	Meleagris gallopavo	81.44	0.00e+00	1921.00
IUUC-Mmr-061003	Microcebus murinus	92.45	0.00e+00	2162.00
IUUC-Mmu-063584	Mus musculus	90.51	0.00e+00	2099.00
IUUC-Mpu-066056	Mustela putorius furo	92.46	0.00e+00	2142.00
IUUC-Mlu-067850	Myotis lucifugus	92.34	0.00e+00	2185.00
IUUC-Nle-069837	Nomascus leucogenys	91.88	0.00e+00	1977.00
IUUC-Opr-070943	Ochotona princeps	86.76	0.00e+00	2023.00
IUUC-Ont-071663	Oreochromis niloticus	62.84	0.00e+00	1486.00
IUUC-Oan-072934	Ornithorhynchus anatinus	75.16	0.00e+00	1258.00
IUUC-Ocu-074706	Oryctolagus cuniculus	92.52	0.00e+00	2170.00
IUUC-Ola-086543	Oryzias latipes	60.40	0.00e+00	1445.00
IUUC-Oga-088671	Otolemur garnettii	77.46	0.00e+00	936.00
IUUC-Oar-089560	Ovis aries	87.57	0.00e+00	2076.00
IUUC-Ptr-090875	Pan troglodytes	93.23	0.00e+00	2257.00
IUUC-Pan-091788	Papio anubis	91.69	0.00e+00	2175.00
IUUC-Psi-093382	Pelodiscus sinensis	80.86	0.00e+00	1920.00
IUUC-Pfo-096272	Poecilia formosa	60.64	0.00e+00	1404.00
IUUC-Pab-097907	Pongo abelii	88.77	0.00e+00	2071.00
IUUC-Pca-100628	Procavia capensis	80.42	0.00e+00	1726.00
IUUC-Pva-102956	Pteropus vampyrus	92.68	0.00e+00	1167.00
IUUC-Rno-105722	Rattus norvegicus	93.72	0.00e+00	1803.00
IUUC-Sha-106626	Sarcophilus harrisii	77.98	0.00e+00	1766.00
IUUC-Ssc-115918	Sus scrofa	91.68	0.00e+00	1687.00
IUUC-Tru-118638	Takifugu rubripes	65.71	0.00e+00	891.00
IUUC-Tsy-118820	Tarsius syrichta	91.93	0.00e+00	766.00
IUUC-Tbe-127654	Tupaia belangeri	77.75	0.00e+00	1603.00
IUUC-Ttr-128821	Tursiops truncatus	85.00	0.00e+00	2014.00
IUUC-Xtr-131823	Xenopus tropicalis	72.35	0.00e+00	1641.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence