iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053623

UUCD1 version

UUC-LoA-00742

Ensembl Protein ID

ENSLAFP00000023218.1

UniProt Accession

G3U5W0; G3U5W0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000027865.1	ENSLAFT00000030345.1	ENSLAFP00000029133.1
ENSLAFG00000027865.1	ENSLAFT00000033836.1	ENSLAFP00000023218.1
ENSLAFG00000027865.1	ENSLAFT00000025578.1	ENSLAFP00000021565.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-14	54.4	629	694

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 629  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 694
           79*********9977765156789*********************************..*******85 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEAEKDSGRR LRPIDRQRYD ENEDLSDVEE IVSVRGFSLE EKLRSQLYQG DFVHAMEGKD 60
FNYEYVQREA LRVPLIFREK DGLGIKMPDP DFTVRDVKLL VGSRRLVDVM DVNTQKGTEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCAG AGAAAGACTC TGGAAGAAGA TTGGTGTGTA GCTTTTTTTT TTTTTTCCCC 60
CAAATCTGTA TCTGGTATAT GATAGATCTT TTTTTTTTTG GTTTCCTGCT GCCTTTTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	95.81	0.00e+00	2291.00
IUUC-Apl-003787	Anas platyrhynchos	84.00	0.00e+00	1916.00
IUUC-Aca-004247	Anolis carolinensis	78.70	0.00e+00	1820.00
IUUC-Ame-011463	Astyanax mexicanus	74.17	2.00e-171	596.00
IUUC-Bta-013531	Bos taurus	95.95	0.00e+00	2320.00
IUUC-Cel-018303	Caenorhabditis elegans	44.24	7.00e-82	298.00
IUUC-Cja-018876	Callithrix jacchus	92.12	0.00e+00	2133.00
IUUC-Cfa-020857	Canis familiaris	96.34	0.00e+00	2331.00
IUUC-Cpo-021967	Cavia porcellus	92.43	0.00e+00	2122.00
IUUC-Csa-023210	Chlorocebus sabaeus	96.36	0.00e+00	2263.00
IUUC-Dre-028272	Danio rerio	63.48	0.00e+00	1523.00
IUUC-Dno-030034	Dasypus novemcinctus	95.42	0.00e+00	2244.00
IUUC-Dor-030736	Dipodomys ordii	86.15	0.00e+00	989.00
IUUC-Eca-034255	Equus caballus	96.79	0.00e+00	2222.00
IUUC-Eeu-035038	Erinaceus europaeus	98.10	0.00e+00	1184.00
IUUC-Fca-035786	Felis catus	96.01	0.00e+00	2275.00
IUUC-Fal-037589	Ficedula albicollis	83.54	0.00e+00	2032.00
IUUC-Gmo-038781	Gadus morhua	63.15	0.00e+00	689.00
IUUC-Gga-041103	Gallus gallus	85.65	0.00e+00	1127.00
IUUC-Gac-041304	Gasterosteus aculeatus	58.98	0.00e+00	1018.00
IUUC-Ggo-044522	Gorilla gorilla	95.51	0.00e+00	1712.00
IUUC-Hsa-045877	Homo sapiens	96.21	0.00e+00	2269.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	96.46	0.00e+00	1307.00
IUUC-Lch-049950	Latimeria chalumnae	78.67	0.00e+00	1913.00
IUUC-Loc-051972	Lepisosteus oculatus	75.99	0.00e+00	1092.00
IUUC-Mcc-054943	Macaca mulatta	96.45	0.00e+00	2261.00
IUUC-Meu-056259	Macropus eugenii	85.78	0.00e+00	2054.00
IUUC-Mga-059671	Meleagris gallopavo	84.31	0.00e+00	1971.00
IUUC-Mmr-061003	Microcebus murinus	95.72	0.00e+00	2295.00
IUUC-Mdo-062017	Monodelphis domestica	80.98	0.00e+00	661.00
IUUC-Mmu-063584	Mus musculus	93.66	0.00e+00	2228.00
IUUC-Mpu-066056	Mustela putorius furo	96.18	0.00e+00	2292.00
IUUC-Mlu-067850	Myotis lucifugus	95.49	0.00e+00	2281.00
IUUC-Nle-069837	Nomascus leucogenys	93.08	0.00e+00	2024.00
IUUC-Opr-070943	Ochotona princeps	92.45	0.00e+00	2130.00
IUUC-Ont-071663	Oreochromis niloticus	66.11	0.00e+00	1580.00
IUUC-Oan-072934	Ornithorhynchus anatinus	75.57	0.00e+00	1247.00
IUUC-Ocu-074706	Oryctolagus cuniculus	95.45	0.00e+00	2288.00
IUUC-Ola-086543	Oryzias latipes	64.12	0.00e+00	1550.00
IUUC-Oga-088671	Otolemur garnettii	82.39	0.00e+00	995.00
IUUC-Oar-089560	Ovis aries	91.05	0.00e+00	2221.00
IUUC-Ptr-090875	Pan troglodytes	96.37	0.00e+00	2297.00
IUUC-Pan-091788	Papio anubis	93.91	0.00e+00	2202.00
IUUC-Psi-093382	Pelodiscus sinensis	83.84	0.00e+00	2026.00
IUUC-Pfo-096272	Poecilia formosa	62.61	0.00e+00	1506.00
IUUC-Pab-097907	Pongo abelii	91.73	0.00e+00	2117.00
IUUC-Pca-100628	Procavia capensis	88.64	0.00e+00	1875.00
IUUC-Pva-102956	Pteropus vampyrus	94.17	0.00e+00	1170.00
IUUC-Rno-105722	Rattus norvegicus	94.16	0.00e+00	1794.00
IUUC-Sha-106626	Sarcophilus harrisii	81.40	0.00e+00	1839.00
IUUC-Ssc-115918	Sus scrofa	95.53	0.00e+00	1748.00
IUUC-Tru-118638	Takifugu rubripes	69.23	0.00e+00	987.00
IUUC-Tsy-118820	Tarsius syrichta	91.91	0.00e+00	762.00
IUUC-Tbe-127654	Tupaia belangeri	80.32	0.00e+00	1687.00
IUUC-Ttr-128821	Tursiops truncatus	89.01	0.00e+00	2065.00
IUUC-Xtr-131823	Xenopus tropicalis	75.56	0.00e+00	1746.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence