iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012705

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

CBLC protein

Genbank Nucleotide ID

DAAA02047337

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000009494.4	ENSBTAT00000043713.2	ENSBTAP00000041264.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	84.52	0.00e+00	669.00	IUUC-Hsa-045735

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MAAAALRGRQ WGESRAFGRA VRLLQRLEEQ CGDPRLSSSP PSLRDLLPRT AQLLRQVAQA 60
RREAGGGVPE GPGGPWDFLM VYLANLEAKS RQVAALLPPH GRKIANDELF REGSRLRRQL 120

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Nucleotide Sequence
(Fasta)

ATCAGAAGGA CCCATGGCTG CGGCGGCCCT GCGGGGACGA CAGTGGGGAG AATCCCGCGC 60
GTTCGGCCGC GCAGTGAGGC TGCTGCAGCG CCTGGAAGAA CAATGCGGGG ACCCCCGGCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006508--P:proteolysis

KEGG

bta:615866

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	79.96	0.00e+00	717.00
IUUC-Cja-019179	Callithrix jacchus	83.37	0.00e+00	699.00
IUUC-Cfa-020593	Canis familiaris	77.49	0.00e+00	706.00
IUUC-Cpo-021289	Cavia porcellus	76.20	2.00e-176	612.00
IUUC-Csa-023966	Chlorocebus sabaeus	77.73	0.00e+00	662.00
IUUC-Dor-030246	Dipodomys ordii	77.56	2.00e-125	442.00
IUUC-Eca-033921	Equus caballus	74.17	3.00e-152	531.00
IUUC-Fca-035747	Felis catus	64.48	6.00e-165	573.00
IUUC-Ggo-044622	Gorilla gorilla	86.27	1.00e-159	555.00
IUUC-Hsa-045735	Homo sapiens	84.52	0.00e+00	699.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	79.57	0.00e+00	630.00
IUUC-Laf-053983	Loxodonta africana	77.80	0.00e+00	729.00
IUUC-Mmr-061310	Microcebus murinus	77.59	0.00e+00	662.00
IUUC-Mmu-064155	Mus musculus	70.14	0.00e+00	664.00
IUUC-Mpu-066655	Mustela putorius furo	74.76	0.00e+00	696.00
IUUC-Mlu-067929	Myotis lucifugus	86.05	5.00e-156	543.00
IUUC-Nle-070065	Nomascus leucogenys	70.19	2.00e-160	558.00
IUUC-Ocu-074049	Oryctolagus cuniculus	69.27	2.00e-129	455.00
IUUC-Oga-087952	Otolemur garnettii	80.28	0.00e+00	697.00
IUUC-Oar-089382	Ovis aries	93.69	0.00e+00	806.00
IUUC-Ptr-090579	Pan troglodytes	67.96	4.00e-126	444.00
IUUC-Pan-092075	Papio anubis	82.86	0.00e+00	657.00
IUUC-Pab-098100	Pongo abelii	74.52	3.00e-173	601.00
IUUC-Pca-100830	Procavia capensis	80.16	5.00e-113	401.00
IUUC-Pva-102714	Pteropus vampyrus	79.05	2.00e-168	585.00
IUUC-Rno-105348	Rattus norvegicus	72.55	0.00e+00	667.00
IUUC-Sha-107138	Sarcophilus harrisii	63.64	4.00e-124	437.00
IUUC-Ssc-116424	Sus scrofa	82.04	0.00e+00	792.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence