iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074049

UUCD1 version

UUC-OrC-00783

Ensembl Protein ID

ENSOCUP00000020938.1

UniProt Accession

G1TV56; G1TV56_RABIT

Protein Name

Uncharacterized protein

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000024783.1	ENSOCUT00000022099.1	ENSOCUP00000020938.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.60e-07	30.6	234	273

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ + +Cl +w     + s + +CP Cr
   Q: 234  CKICAERNKD-VRIEPCGHLLCSHCLGAW-----QHSDSRTCPFCR 273
           99********.******************.....6889999****8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

RRQLAKLALI FSHMHAELHA LFPGGKYRGH EYQLTKAPAQ ALWRAHCGAR CVLPWAEFES 60
LLGTCHPVEP GPTALALRST VDLTCSGHVS IFEFDIFTRL FQPWPTLLKN WQLLAVNHPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCGGCAGC TGGCCAAGCT GGCCCTCATC TTCAGCCACA TGCACGCCGA GCTGCACGCG 60
CTCTTCCCGG GGGGCAAGTA CCGCGGCCAC GAGTACCAGC TCACCAAGGC CCCGGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	65.62	7.00e-137	480.00
IUUC-Bta-012705	Bos taurus	69.27	1.00e-133	469.00
IUUC-Cja-019179	Callithrix jacchus	76.01	1.00e-132	466.00
IUUC-Cfa-020593	Canis familiaris	66.41	1.00e-136	479.00
IUUC-Cpo-021289	Cavia porcellus	73.70	2.00e-123	436.00
IUUC-Csa-023966	Chlorocebus sabaeus	75.42	9.00e-134	470.00
IUUC-Dor-030246	Dipodomys ordii	84.04	8.00e-94	337.00
IUUC-Fca-035747	Felis catus	62.60	2.00e-126	445.00
IUUC-Ggo-044622	Gorilla gorilla	77.03	2.00e-133	468.00
IUUC-Hsa-045735	Homo sapiens	77.03	3.00e-134	471.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	70.62	2.00e-131	462.00
IUUC-Laf-053983	Loxodonta africana	68.83	9.00e-135	473.00
IUUC-Mmr-061310	Microcebus murinus	68.49	2.00e-129	455.00
IUUC-Mmu-064155	Mus musculus	75.26	9.00e-130	456.00
IUUC-Mpu-066655	Mustela putorius furo	59.16	6.00e-125	441.00
IUUC-Mlu-067929	Myotis lucifugus	75.19	4.00e-116	410.00
IUUC-Nle-070065	Nomascus leucogenys	65.54	2.00e-106	378.00
IUUC-Oga-087952	Otolemur garnettii	76.01	4.00e-135	474.00
IUUC-Oar-089382	Ovis aries	67.45	1.00e-126	446.00
IUUC-Pan-092075	Papio anubis	75.76	4.00e-134	471.00
IUUC-Pab-098100	Pongo abelii	67.57	2.00e-108	385.00
IUUC-Pca-100830	Procavia capensis	83.80	6.00e-70	258.00
IUUC-Pva-102714	Pteropus vampyrus	73.95	4.00e-112	397.00
IUUC-Rno-105348	Rattus norvegicus	75.87	5.00e-128	451.00
IUUC-Ssc-116424	Sus scrofa	67.97	1.00e-141	496.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence