iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098100

Ensembl Protein ID

ENSPPYP00000011295.2

UniProt Accession

H2NZ61; H2NZ61_PONAB

Genbank Protein ID

ENSPPYP00000011295

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01223182

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000010096.2	ENSPPYT00000011735.2	ENSPPYP00000011295.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.40	0.00e+00	770.00	IUUC-Hsa-045735

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MALAVAPWGR QWEEARALGR AVRMLQRLEE QCGDPRLSIS PPSLRDLLPR TAQLLREVAH 60
SRRAAGGGGP GGPGGCGDFL LIYLANLEAK GRQVAALLPP RGRRSANDEL FRAGSRLRRQ 120

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Nucleotide Sequence
(Fasta)

CACCGGTCCT TCCTGGCACA CGCGAGGCTC TCATGGCTCT GGCGGTGGCC CCGTGGGGGC 60
GACAGTGGGA AGAGGCCCGC GCCCTGGGCC GGGCAGTCAG GATGCTGCAG CGCCTAGAAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2

PROSITE

PS51506--CBL_PTB

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	73.91	4.00e-154	537.00
IUUC-Bta-012705	Bos taurus	74.52	3.00e-162	565.00
IUUC-Cja-019179	Callithrix jacchus	80.38	0.00e+00	699.00
IUUC-Cfa-020593	Canis familiaris	69.80	8.00e-150	523.00
IUUC-Cpo-021289	Cavia porcellus	67.38	6.00e-146	510.00
IUUC-Csa-023966	Chlorocebus sabaeus	83.66	0.00e+00	661.00
IUUC-Dor-030246	Dipodomys ordii	78.03	1.00e-128	452.00
IUUC-Eca-033921	Equus caballus	62.67	6.00e-121	427.00
IUUC-Fca-035747	Felis catus	59.55	1.00e-128	453.00
IUUC-Ggo-044622	Gorilla gorilla	85.15	1.00e-164	572.00
IUUC-Hsa-045735	Homo sapiens	88.40	0.00e+00	760.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	72.93	2.00e-139	488.00
IUUC-Laf-053983	Loxodonta africana	72.59	5.00e-165	573.00
IUUC-Mmr-061310	Microcebus murinus	71.39	2.00e-160	559.00
IUUC-Mmu-064155	Mus musculus	66.67	2.00e-158	552.00
IUUC-Mpu-066655	Mustela putorius furo	73.08	8.00e-160	556.00
IUUC-Mlu-067929	Myotis lucifugus	81.40	6.00e-125	439.00
IUUC-Nle-070065	Nomascus leucogenys	81.42	3.00e-177	614.00
IUUC-Ocu-074049	Oryctolagus cuniculus	67.57	2.00e-108	385.00
IUUC-Oga-087952	Otolemur garnettii	74.36	0.00e+00	633.00
IUUC-Oar-089382	Ovis aries	70.70	8.00e-155	540.00
IUUC-Ptr-090579	Pan troglodytes	69.95	2.00e-127	448.00
IUUC-Pan-092075	Papio anubis	84.60	0.00e+00	703.00
IUUC-Pca-100830	Procavia capensis	79.84	1.00e-110	393.00
IUUC-Pva-102714	Pteropus vampyrus	83.01	4.00e-143	501.00
IUUC-Rno-105348	Rattus norvegicus	67.35	2.00e-158	551.00
IUUC-Ssc-116424	Sus scrofa	72.94	2.00e-162	565.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence