iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003435

Ensembl Protein ID

ENSAPLP00000008097.1

UniProt Accession

R0K4G5; R0K4G5_ANAPL

Genbank Protein ID

EOB04951.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase 38

Genbank Nucleotide ID

ADON01038478

Gene Name

USP38; Anapl_03323

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008408.1	ENSAPLT00000008768.1	ENSAPLP00000008097.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.30e-83	278.7	339	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+ +l+ + + +n         +l+++lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 339  TGLINLGNTCYMNSVIQALFMATDFRRHVLSLNLNGCN---------SLMRKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 416
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk.....eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           qD++E+l+flld+l+ee k      +   +  e++++d+s++++         +     +++++li+++F+g+lk++i cl+c+++s++
   Q: 417  QDCSEYLRFLLDRLHEEEKTlkalsS--AKAPESRKNDESQTQETvhkaqvfaEAPCLGREERTLIEKMFGGKLKTTICCLNCKSTSQK 503
           ******************77666442..33333333333333333445666555555666777************************** PP
   S: 166  eepfldlslpvpgkeetkke..................................................................... 185
           ee f+dlsl++    + ++                                                                      
   Q: 504  EEAFTDLSLAFCPPASLENVgskcvdcsemkddcgvetstsatipagetplnsveinggcdavtnegttkdlsaepnsetnselnkgqe 592
           ***********988866555899****************************************************************** PP
   S: 186  ..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
                         s++d+L+ f ++e l g+nkyycekc ++q+aek++++ + Pe+Lil L Rfs++ + + r+ki ++v++pl L+
   Q: 593  nrdmsqrlvgkntpSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIIEEPEYLILTLLRFSYDPKCHIRRKILDNVSLPLVLE 681
           ***************************************************************************************99 PP
   S: 261  lspfcts................................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn.......... 301
           l   +++                                +     e      + Y L++vvvHsG s++sGHY++y++n          
   Q: 682  LPVKTATsplpvvsggwsvdvevsdtgenlakklkpsgaD-----EvscpqLVPYTLSSVVVHSGvSSESGHYYSYARNvtgsgpsglr 765
           9864444578888888888888877777766666655553.....0445449************************************* PP
   S: 302  ................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                            +++W+lf+Ds+Vt ++ ++v++ t+    +taYvlfYk++
   Q: 766  hqskalslvcsqnkllaeespctvieneldaeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLFYKKQ 838
           *********999999999999999888877755777*******************999*************86 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

QAGLRLIMSC PSVLELFELL QVEALRLVCE RPAPPLCARL CQLLGDFPQC LPRGRKLSLA 60
FCQQLVRSIA HFQSQGSREA ELRLYVSQVT QVSGLLRSVW KAEPDTLLPS LQELFAVISA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCCGGGC TGCGCCTGAT CATGAGCTGC CCGTCGGTGC TGGAGCTCTT CGAGCTGCTG 60
CAGGTGGAGG CGCTGCGCCT GGTGTGCGAG CGGCCGGCGC CGCCGCTCTG CGCCCGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	75.05	0.00e+00	1274.00
IUUC-Aca-004556	Anolis carolinensis	78.48	0.00e+00	1316.00
IUUC-Ame-010616	Astyanax mexicanus	61.48	0.00e+00	1056.00
IUUC-Bta-013544	Bos taurus	75.94	0.00e+00	1294.00
IUUC-Cja-018745	Callithrix jacchus	74.63	0.00e+00	1281.00
IUUC-Cfa-020434	Canis familiaris	75.51	0.00e+00	1298.00
IUUC-Cpo-021666	Cavia porcellus	76.04	0.00e+00	1253.00
IUUC-Csa-023965	Chlorocebus sabaeus	76.65	0.00e+00	1351.00
IUUC-Cho-024809	Choloepus hoffmanni	68.86	0.00e+00	981.00
IUUC-Csv-026333	Ciona savignyi	43.82	5.00e-32	130.00
IUUC-Dre-028338	Danio rerio	60.31	0.00e+00	1035.00
IUUC-Dno-029372	Dasypus novemcinctus	75.77	0.00e+00	1305.00
IUUC-Dor-030752	Dipodomys ordii	74.13	0.00e+00	1004.00
IUUC-Dme-031871	Drosophila melanogaster	29.38	1.00e-46	181.00
IUUC-Ete-032588	Echinops telfairi	67.62	0.00e+00	913.00
IUUC-Eca-034416	Equus caballus	76.44	0.00e+00	1329.00
IUUC-Eeu-035132	Erinaceus europaeus	59.62	0.00e+00	974.00
IUUC-Fca-036137	Felis catus	75.85	0.00e+00	1321.00
IUUC-Fal-037297	Ficedula albicollis	91.09	0.00e+00	1607.00
IUUC-Gmo-038727	Gadus morhua	63.80	0.00e+00	858.00
IUUC-Gga-041091	Gallus gallus	91.83	0.00e+00	1591.00
IUUC-Gac-042082	Gasterosteus aculeatus	60.29	0.00e+00	988.00
IUUC-Ggo-045376	Gorilla gorilla	71.55	0.00e+00	1191.00
IUUC-Hsa-046444	Homo sapiens	76.33	0.00e+00	1319.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	75.91	0.00e+00	1320.00
IUUC-Lch-050500	Latimeria chalumnae	68.25	0.00e+00	1212.00
IUUC-Loc-052625	Lepisosteus oculatus	64.61	0.00e+00	1120.00
IUUC-Laf-053689	Loxodonta africana	75.77	0.00e+00	1318.00
IUUC-Mcc-055286	Macaca mulatta	76.65	0.00e+00	1312.00
IUUC-Mga-059905	Meleagris gallopavo	90.83	0.00e+00	1571.00
IUUC-Mmr-061397	Microcebus murinus	76.89	0.00e+00	1318.00
IUUC-Mdo-062833	Monodelphis domestica	77.80	0.00e+00	1387.00
IUUC-Mmu-063157	Mus musculus	74.44	0.00e+00	1277.00
IUUC-Mpu-066434	Mustela putorius furo	76.33	0.00e+00	1318.00
IUUC-Mlu-068178	Myotis lucifugus	75.45	0.00e+00	1268.00
IUUC-Nle-070153	Nomascus leucogenys	75.80	0.00e+00	1269.00
IUUC-Ont-072330	Oreochromis niloticus	61.35	0.00e+00	1065.00
IUUC-Oan-072709	Ornithorhynchus anatinus	78.55	0.00e+00	1230.00
IUUC-Ocu-074832	Oryctolagus cuniculus	76.01	0.00e+00	1307.00
IUUC-Ola-087003	Oryzias latipes	54.64	7.00e-45	172.00
IUUC-Oga-088517	Otolemur garnettii	73.33	0.00e+00	1262.00
IUUC-Oar-089472	Ovis aries	73.19	0.00e+00	1230.00
IUUC-Ptr-090996	Pan troglodytes	76.01	0.00e+00	1313.00
IUUC-Pan-091837	Papio anubis	74.81	0.00e+00	1293.00
IUUC-Psi-093236	Pelodiscus sinensis	84.06	0.00e+00	1306.00
IUUC-Pfo-097193	Poecilia formosa	60.72	0.00e+00	996.00
IUUC-Pab-098710	Pongo abelii	75.88	0.00e+00	1322.00
IUUC-Pca-100794	Procavia capensis	66.45	0.00e+00	1096.00
IUUC-Pva-102722	Pteropus vampyrus	74.87	0.00e+00	1285.00
IUUC-Rno-105743	Rattus norvegicus	74.87	0.00e+00	1271.00
IUUC-Sha-106563	Sarcophilus harrisii	78.34	0.00e+00	1285.00
IUUC-Sar-113533	Sorex araneus	66.20	0.00e+00	1101.00
IUUC-Ssc-116259	Sus scrofa	86.51	0.00e+00	695.00
IUUC-Tgu-117475	Taeniopygia guttata	90.77	0.00e+00	1604.00
IUUC-Tru-118623	Takifugu rubripes	60.40	0.00e+00	984.00
IUUC-Tsy-119250	Tarsius syrichta	77.23	0.00e+00	1173.00
IUUC-Tni-120441	Tetraodon nigroviridis	57.37	0.00e+00	905.00
IUUC-Tbe-127936	Tupaia belangeri	63.93	0.00e+00	1005.00
IUUC-Ttr-128483	Tursiops truncatus	63.96	0.00e+00	1048.00
IUUC-Vpa-130303	Vicugna pacos	89.20	0.00e+00	785.00
IUUC-Xtr-132773	Xenopus tropicalis	68.91	0.00e+00	1179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence