iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	8.50e-16	58.3	44	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksllrll 80
           +vr+k++++ge r+  +++++p+ +ed++++v+t   ++++ ++l+Y++++ +++ lk+++dldka+++l+   s+ksl r+l
   Q: 44   DVRIKFEHNGERRI--IAFSRPVRYEDVEHKVTT---VFGQPLDLHYMNNELSIL-LKNQDDLDKAIDILDrsaSMKSL-RIL 119
           59**********77..******************...******************.***************87666666.444 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDEQEALDSI MKDLVALQMS RRPRVSGYET MKNKDTGHPN RQSDVRIKFE HNGERRIIAF 60
SRPVRYEDVE HKVTTVFGQP LDLHYMNNEL SILLKNQDDL DKAIDILDRS ASMKSLRILL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCTGGACT TCAAGACTGG CAGGCGGGCC AGCCGAGTGG CGCCGCCGAG GCCGGGTTGG 60
GCCGAGCCTG GGAGCGCCGG GGATGTAGCG GGCCACCCTG CTCATGCCAC AGCGCCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom

PROSITE

PS51745--PB1
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00564--PB1
PF00069--Pkinase

SMART

SM00666--PB1
SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004702--F:signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0030036--P:actin cytoskeleton organization
GO:0001568--P:blood vessel development
GO:0035556--P:intracellular signal transduction
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1900745--P:positive regulation of p38MAPK cascade
GO:0046777--P:protein autophosphorylation

KEGG

rno:303604

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001464	Ailuropoda melanoleuca	92.68	0.00e+00	1251.00
IUUC-Ame-011807	Astyanax mexicanus	76.63	0.00e+00	959.00
IUUC-Bta-012717	Bos taurus	96.80	0.00e+00	1259.00
IUUC-Cja-019548	Callithrix jacchus	95.93	0.00e+00	1135.00
IUUC-Cfa-020785	Canis familiaris	96.96	0.00e+00	1266.00
IUUC-Cpo-021444	Cavia porcellus	96.80	0.00e+00	1259.00
IUUC-Csa-023898	Chlorocebus sabaeus	91.78	0.00e+00	1246.00
IUUC-Cin-025443	Ciona intestinalis	44.94	5.00e-135	474.00
IUUC-Dre-027587	Danio rerio	76.63	0.00e+00	991.00
IUUC-Dno-028984	Dasypus novemcinctus	91.17	0.00e+00	1236.00
IUUC-Eca-034089	Equus caballus	97.12	0.00e+00	1265.00
IUUC-Fca-035656	Felis catus	96.92	0.00e+00	1244.00
IUUC-Ggo-045339	Gorilla gorilla	91.78	0.00e+00	1246.00
IUUC-Hsa-046137	Homo sapiens	96.33	0.00e+00	1259.00
IUUC-Itr-048091	Ictidomys tridecemlineatus	97.60	0.00e+00	1274.00
IUUC-Loc-052751	Lepisosteus oculatus	75.84	0.00e+00	1024.00
IUUC-Laf-054342	Loxodonta africana	95.54	0.00e+00	1242.00
IUUC-Mcc-055631	Macaca mulatta	91.63	0.00e+00	1243.00
IUUC-Mga-059565	Meleagris gallopavo	85.14	0.00e+00	1095.00
IUUC-Mmr-060745	Microcebus murinus	91.77	0.00e+00	1241.00
IUUC-Mmu-063432	Mus musculus	98.88	0.00e+00	1293.00
IUUC-Mpu-066544	Mustela putorius furo	92.27	0.00e+00	1232.00
IUUC-Mlu-067655	Myotis lucifugus	96.01	0.00e+00	1254.00
IUUC-Nle-070048	Nomascus leucogenys	85.67	0.00e+00	1123.00
IUUC-Ont-071889	Oreochromis niloticus	77.00	0.00e+00	994.00
IUUC-Oan-073137	Ornithorhynchus anatinus	76.75	0.00e+00	704.00
IUUC-Ola-087055	Oryzias latipes	72.77	0.00e+00	930.00
IUUC-Oga-088913	Otolemur garnettii	92.04	0.00e+00	1188.00
IUUC-Oar-090321	Ovis aries	92.07	0.00e+00	1246.00
IUUC-Ptr-091046	Pan troglodytes	91.63	0.00e+00	1244.00
IUUC-Pan-092280	Papio anubis	91.49	0.00e+00	1243.00
IUUC-Pfo-096365	Poecilia formosa	76.44	0.00e+00	986.00
IUUC-Pab-097785	Pongo abelii	91.78	0.00e+00	1246.00
IUUC-Pva-102740	Pteropus vampyrus	92.06	0.00e+00	1243.00
IUUC-Ssc-115554	Sus scrofa	96.27	0.00e+00	1234.00
IUUC-Tgu-117312	Taeniopygia guttata	88.64	0.00e+00	1162.00
IUUC-Tni-120426	Tetraodon nigroviridis	75.36	0.00e+00	962.00
IUUC-Ttr-128646	Tursiops truncatus	92.54	0.00e+00	1253.00
IUUC-Xtr-132121	Xenopus tropicalis	82.43	0.00e+00	1064.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence