iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.....qkwpglknssskefrCPlCr 46
           C+iCle + + pl+ +CgH f++ C+     + +     +  ++ +CP+Cr
   Q: 15   CPICLELLTE-PLSIDCGHSFCQACIignsdNSV----LNPEGKSSCPVCR 60
           ********99.**************987554444....56678888****8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTSAVLVDIR DEVTCPICLE LLTEPLSIDC GHSFCQACII GNSDNSVLNP EGKSSCPVCR 60
TVYQPGSLRP NRHLAAIVKR LREVVLGPGK QLEVIFCALH GEKLQLFCKE DGKLICWLCE 120

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Nucleotide Sequence
(Fasta)

CGCACTGATC CAGGCCACGG ATTCCAGGTT AGTGAGCAAA CCCATTTTCT GAAAAGTCGT 60
GCTGTCCCAC TGAGTCTGTG CCGCCTTACA GGTTGTGTTG GGGCTCACGC GTGGAAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035458--P:cellular response to interferon-beta
GO:0098586--P:cellular response to virus
GO:0010994--P:free ubiquitin chain polymerization
GO:2000737--P:negative regulation of stem cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045071--P:negative regulation of viral genome replication
GO:0002741--P:positive regulation of cytokine secretion involved in immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0010628--P:positive regulation of gene expression
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0070206--P:protein trimerization
GO:0032496--P:response to lipopolysaccharide

KEGG

rno:293294

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001965	Ailuropoda melanoleuca	79.92	0.00e+00	774.00
IUUC-Bta-013110	Bos taurus	52.41	5.00e-147	514.00
IUUC-Cel-018621	Caenorhabditis elegans	30.00	1.00e-08	54.30
IUUC-Cja-019944	Callithrix jacchus	50.71	1.00e-130	459.00
IUUC-Csa-023785	Chlorocebus sabaeus	56.43	9.00e-152	530.00
IUUC-Cho-024416	Choloepus hoffmanni	57.59	1.00e-85	310.00
IUUC-Dno-029492	Dasypus novemcinctus	53.75	4.00e-147	515.00
IUUC-Dor-030480	Dipodomys ordii	79.00	2.00e-133	469.00
IUUC-Ete-033021	Echinops telfairi	46.87	5.00e-107	381.00
IUUC-Eca-034235	Equus caballus	54.11	6.00e-146	510.00
IUUC-Eeu-034968	Erinaceus europaeus	47.13	5.00e-102	364.00
IUUC-Fca-035533	Felis catus	79.30	0.00e+00	775.00
IUUC-Hsa-046006	Homo sapiens	81.15	0.00e+00	821.00
IUUC-Itr-048069	Ictidomys tridecemlineatus	80.81	0.00e+00	771.00
IUUC-Lpe-051499	Leersia perrieri	41.43	9.00e-09	54.30
IUUC-Laf-053805	Loxodonta africana	78.69	0.00e+00	725.00
IUUC-Mcc-054743	Macaca mulatta	55.22	1.00e-148	520.00
IUUC-Mmr-061023	Microcebus murinus	78.76	0.00e+00	741.00
IUUC-Mmu-063682	Mus musculus	93.65	0.00e+00	914.00
IUUC-Mpu-065842	Mustela putorius furo	79.88	0.00e+00	774.00
IUUC-Mlu-067695	Myotis lucifugus	53.74	3.00e-134	471.00
IUUC-Nle-068980	Nomascus leucogenys	55.62	1.00e-148	519.00
IUUC-Opr-071057	Ochotona princeps	50.72	4.00e-119	421.00
IUUC-Oga-088267	Otolemur garnettii	79.63	0.00e+00	778.00
IUUC-Ptr-090573	Pan troglodytes	81.35	0.00e+00	823.00
IUUC-Pan-092745	Papio anubis	81.35	0.00e+00	811.00
IUUC-Pab-098535	Pongo abelii	55.22	6.00e-147	514.00
IUUC-Sar-113094	Sorex araneus	47.25	5.00e-105	374.00
IUUC-Ssc-115715	Sus scrofa	53.24	1.00e-136	479.00
IUUC-Tur-126362	Triticum urartu	40.00	2.00e-08	52.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence