iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-047906

Ensembl Protein ID

ENSSTOP00000007452.2

UniProt Accession

I3MBE7; I3MBE7_ICTTR

Genbank Protein ID

ENSSTOP00000007452

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01054004

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000008299.2	ENSSTOT00000008314.2	ENSSTOP00000007452.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	92.79	0.00e+00	1437.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGCCGAGA TGCAGAGCAC TTCTAATCAT CTGTGGCTTT TATCTGATAT CTTAGGCCAA 60
GGAGCTACAG CAAATGTCTT TCGTGGAAGA CATAAGGTTG GTACAGTAAA AACTGAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	96.46	0.00e+00	1472.00
IUUC-Apl-004028	Anas platyrhynchos	85.99	0.00e+00	1340.00
IUUC-Aca-004998	Anolis carolinensis	81.77	0.00e+00	1274.00
IUUC-Ame-011617	Astyanax mexicanus	70.18	0.00e+00	1054.00
IUUC-Bta-012799	Bos taurus	96.05	0.00e+00	1467.00
IUUC-Cja-019357	Callithrix jacchus	96.60	0.00e+00	1476.00
IUUC-Cfa-020309	Canis familiaris	96.05	0.00e+00	1466.00
IUUC-Cpo-022062	Cavia porcellus	95.51	0.00e+00	1458.00
IUUC-Csa-023517	Chlorocebus sabaeus	96.46	0.00e+00	1476.00
IUUC-Cho-025037	Choloepus hoffmanni	93.36	0.00e+00	965.00
IUUC-Cin-025580	Ciona intestinalis	39.75	2.00e-145	509.00
IUUC-Csv-025818	Ciona savignyi	39.63	3.00e-139	489.00
IUUC-Dre-027527	Danio rerio	69.89	0.00e+00	1064.00
IUUC-Dno-029475	Dasypus novemcinctus	85.74	0.00e+00	1145.00
IUUC-Dme-031698	Drosophila melanogaster	38.70	1.00e-128	453.00
IUUC-Ete-033090	Echinops telfairi	82.04	0.00e+00	1217.00
IUUC-Eca-033996	Equus caballus	94.69	0.00e+00	1457.00
IUUC-Eeu-035082	Erinaceus europaeus	87.76	0.00e+00	857.00
IUUC-Fca-035921	Felis catus	93.09	0.00e+00	1415.00
IUUC-Fal-037406	Ficedula albicollis	85.85	0.00e+00	1343.00
IUUC-Gmo-038721	Gadus morhua	70.60	0.00e+00	1043.00
IUUC-Gga-041234	Gallus gallus	85.31	0.00e+00	1337.00
IUUC-Gac-042315	Gasterosteus aculeatus	70.86	0.00e+00	1059.00
IUUC-Ggo-044885	Gorilla gorilla	90.07	0.00e+00	1363.00
IUUC-Hsa-046847	Homo sapiens	96.33	0.00e+00	1474.00
IUUC-Lch-049731	Latimeria chalumnae	54.03	0.00e+00	766.00
IUUC-Loc-051879	Lepisosteus oculatus	72.75	0.00e+00	1101.00
IUUC-Laf-054232	Loxodonta africana	94.83	0.00e+00	1456.00
IUUC-Mcc-055447	Macaca mulatta	96.60	0.00e+00	1478.00
IUUC-Meu-056138	Macropus eugenii	94.93	0.00e+00	669.00
IUUC-Mga-059460	Meleagris gallopavo	84.63	0.00e+00	1318.00
IUUC-Mmr-061445	Microcebus murinus	96.60	0.00e+00	1472.00
IUUC-Mmu-064107	Mus musculus	92.79	0.00e+00	1410.00
IUUC-Mpu-066834	Mustela putorius furo	96.33	0.00e+00	1473.00
IUUC-Mlu-068006	Myotis lucifugus	92.24	0.00e+00	1390.00
IUUC-Nle-069280	Nomascus leucogenys	96.19	0.00e+00	1473.00
IUUC-Opr-070728	Ochotona princeps	88.16	0.00e+00	1183.00
IUUC-Ont-071621	Oreochromis niloticus	71.88	0.00e+00	1073.00
IUUC-Oan-073162	Ornithorhynchus anatinus	89.94	0.00e+00	1347.00
IUUC-Ocu-074787	Oryctolagus cuniculus	96.87	0.00e+00	1479.00
IUUC-Ola-086737	Oryzias latipes	32.89	2.00e-26	114.00
IUUC-Oga-088764	Otolemur garnettii	94.29	0.00e+00	1448.00
IUUC-Oar-090333	Ovis aries	95.92	0.00e+00	1467.00
IUUC-Ptr-090568	Pan troglodytes	95.92	0.00e+00	1471.00
IUUC-Pan-091979	Papio anubis	96.47	0.00e+00	1474.00
IUUC-Psi-093336	Pelodiscus sinensis	85.71	0.00e+00	1325.00
IUUC-Pma-094200	Petromyzon marinus	43.97	1.00e-173	603.00
IUUC-Pfo-096354	Poecilia formosa	70.82	0.00e+00	1066.00
IUUC-Pab-098499	Pongo abelii	96.46	0.00e+00	1475.00
IUUC-Pva-102454	Pteropus vampyrus	94.42	0.00e+00	1423.00
IUUC-Rno-105595	Rattus norvegicus	92.93	0.00e+00	1407.00
IUUC-Sha-106864	Sarcophilus harrisii	92.38	0.00e+00	1431.00
IUUC-Sar-113728	Sorex araneus	87.25	0.00e+00	1248.00
IUUC-Tgu-117200	Taeniopygia guttata	85.09	0.00e+00	1328.00
IUUC-Tsy-119017	Tarsius syrichta	94.55	0.00e+00	1076.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.22	0.00e+00	1060.00
IUUC-Tbe-127887	Tupaia belangeri	86.32	0.00e+00	1028.00
IUUC-Ttr-129111	Tursiops truncatus	88.44	0.00e+00	1328.00
IUUC-Vpa-130724	Vicugna pacos	96.73	0.00e+00	1474.00
IUUC-Xtr-132091	Xenopus tropicalis	74.08	0.00e+00	1151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence